Facile Synthesis of High Molecular Weight Polypeptides via Fast and Moisture Insensitive Polymerization of α-Amino Acid N-Carboxyanhydrides

Poly(2-Oxazoline) Based Functional Mimics of Peptides to Eradicate MRSA Infections and Persisters While Alleviating Antimicrobial Resistance

(2020) Min Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unsaturated polyurethane films grafted with enantiomeric polylysine promotes macrophage polarization to a M2 phenotype through PI3K/Akt1/mTOR axis

(2020) Yiyuan Duan et al.   BIOMATERIALS

Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

(2019) Jiaguo Huang et al.   NATURE MATERIALS

Synthesis of polypeptides via bioinspired polymerization of in situ purified N-carboxyanhydrides

(2019) Ziyuan Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biofilm Disruption Utilizing α/β Chimeric Polypeptide Molecular Brushes

(2019) Si Zhang et al.   CHINESE JOURNAL OF POLYMER SCIENCE

Aqueous Ring-Opening Polymerization Induced Self-Assembly (ROPISA) of N-carboxyanhydrides

(2019) Chloé Grazon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fast and selective organocatalytic ring-opening polymerization by fluorinated alcohol without a cocatalyst

(2019) Wei Zhao et al.   Nature Communications

A Novel method for the preparation of fluorescent C 60 poly(amino acid) composites and their biological imaging

(2018) Dazhuang Xu et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Triple redox/temperature responsive diselenide-containing homopolypeptide micelles and supramolecular hydrogels thereof

(2018) Yuanfeng Gao et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Macrocyclization of Interferon–Poly(α-amino acid) Conjugates Significantly Improves the Tumor Retention, Penetration, and Antitumor Efficacy

(2018) Yingqin Hou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A S-Sn Lewis Pair-Mediated Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides: Fast Kinetics, High Molecular Weight, and Facile Bioconjugation

(2018) Jingsong Yuan et al.   ACS Macro Letters

Advances and Biomedical Applications of Polypeptide Hydrogels Derived from α-Amino Acid N -Carboxyanhydride (NCA) Polymerizations

(2018) Xianfeng Zhou et al.   Advanced Healthcare Materials

Lithium hexamethyldisilazide initiated superfast ring opening polymerization of alpha-amino acid N-carboxyanhydrides

(2018) Yueming Wu et al.   Nature Communications

Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy

(2017) Xilong Wu et al.   JOURNAL OF CONTROLLED RELEASE

Right-Handed Helical Foldamers Consisting of De Novo d-AApeptides

(2017) Peng Teng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells

(2017) Henry D. Herce et al.   Nature Chemistry

Suppression of Hepatic Inflammation via Systemic siRNA Delivery by Membrane-Disruptive and Endosomolytic Helical Polypeptide Hybrid Nanoparticles

(2016) Hua He et al.   ACS Nano

Phenyl Trimethylsilyl Sulfide-Mediated Controlled Ring-Opening Polymerization of α-Amino Acid N-Carboxyanhydrides

(2016) Jingsong Yuan et al.   BIOMACROMOLECULES

Introducing a Hydrogen-Bond Donor into a Weakly Nucleophilic Brønsted Base: Alkali Metal Hexamethyldisilazides (MHMDS, M=Li, Na, K, Rb and Cs) with Ammonia

(2016) Roman Neufeld et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multifunctional Biocompatible and Biodegradable Folic Acid Conjugated Poly(ε-caprolactone)–Polypeptide Copolymer Vesicles with Excellent Antibacterial Activities

(2015) Mingzhi Wang et al.   BIOCONJUGATE CHEMISTRY

In-situ birth of MSCs multicellular spheroids in poly( l -glutamic acid)/chitosan scaffold for hyaline-like cartilage regeneration

(2015) Kunxi Zhang et al.   BIOMATERIALS

Reversible thermo-sensitivity induced from varying the hydrogen bonding between the side residues of rationally designed polypeptides

(2015) Hong Liu et al.   CHEMICAL COMMUNICATIONS

Primary ammonium/tertiary amine-mediated controlled ring opening polymerisation of amino acid N-carboxyanhydrides

(2015) Charlotte D. Vacogne et al.   CHEMICAL COMMUNICATIONS

Polypeptide brushes grown via surface-initiated ring-opening polymerization of α-amino acid N-carboxyanhydrides

(2015) Yong Shen et al.   CHINESE JOURNAL OF POLYMER SCIENCE

Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold

(2015) James W. Checco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual-pH Sensitive Charge-Reversal Polypeptide Micelles for Tumor-Triggered Targeting Uptake and Nuclear Drug Delivery

(2015) Shi-Song Han et al.   Small

Strategies employed in the design and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials

(2014) Zhan Yuin Ong et al.   ADVANCED DRUG DELIVERY REVIEWS

A new strategy to synthesize bottlebrushes with a helical polyglutamate backbone via N-carboxyanhydride polymerization and RAFT

(2014) Haiwang Lai et al.   CHEMICAL COMMUNICATIONS

Polypeptide films via N-carboxyanhydride ring-opening polymerization (NCA-ROP): past, present and future

(2014) Steven Harris Wibowo et al.   CHEMICAL COMMUNICATIONS

Synthesis of α-hydroxy-ω-aminotelechelic polypeptide from α-amino acid N-carboxyanhydrides catalyzed by alkali-metal borohydrides

(2014) Hui Peng et al.   CHINESE JOURNAL OF POLYMER SCIENCE

Well-Defined Poly(γ-benzyl-l-glutamate)-g-Polytetrahydrofuran: Synthesis, Characterization, and Properties

(2014) An-ru Guo et al.   MACROMOLECULES

Revisiting Secondary Structures in NCA Polymerization: Influences on the Analysis of Protected Polylysines

(2014) David Huesmann et al.   MACROMOLECULES

Intracellular release of doxorubicin from core-crosslinked polypeptide micelles triggered by both pH and reduction conditions

(2013) Liangliang Wu et al.   BIOMATERIALS

Drug and plasmid DNA co-delivery nanocarriers based on abctype polypeptide hybrid miktoarm star copolymers

(2013) Tao Liu et al.   CHINESE JOURNAL OF POLYMER SCIENCE

Nylon-3 Polymers That Enable Selective Culture of Endothelial Cells

(2013) Runhui Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Facile Glovebox-Free Strategy To Significantly Accelerate the Syntheses of Well-Defined Polypeptides by N-Carboxyanhydride (NCA) Ring-Opening Polymerizations

(2013) Jiong Zou et al.   MACROMOLECULES

Functional polypeptide and hybrid materials: Precision synthesis via α-amino acid N-carboxyanhydride polymerization and emerging biomedical applications

(2013) Chao Deng et al.   PROGRESS IN POLYMER SCIENCE

Cationic Peptidopolysaccharides Show Excellent Broad-Spectrum Antimicrobial Activities and High Selectivity

(2012) Peng Li et al.   ADVANCED MATERIALS

N-Heterocyclic Carbene-Mediated Zwitterionic Polymerization of N-Substituted N-Carboxyanhydrides toward Poly(α-peptoid)s: Kinetic, Mechanism, and Architectural Control

(2012) Li Guo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ring opening polymerization of α-amino acid N-carboxyanhydrides catalyzed by rare earth catalysts: Polymerization characteristics and mechanism

(2011) Hui Peng et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Optimization of N-carboxyanhydride (NCA) polymerization by variation of reaction temperature and pressure

(2011) Gijs J. M. Habraken et al.   Polymer Chemistry

General Route toward Side-Chain-Functionalized α-Helical Polypeptides

(2010) Haoyu Tang et al.   BIOMACROMOLECULES

Control of peptide secondary structure on star shape polypeptides tethered to polyhedral oligomeric silsesquioxane nanoparticle through click chemistry

(2010) Shiao-Wei Kuo et al.   POLYMER

High Potency and Broad-Spectrum Antimicrobial Peptides Synthesized via Ring-Opening Polymerization of α-Aminoacid-N-carboxyanhydrides

(2009) Chuncai Zhou et al.   BIOMACROMOLECULES

A Mechanistic Study of α-(Amino acid)-N-carboxyanhydride Polymerization: Comparing Initiation and Termination Events in High-Vacuum and Traditional Polymerization Techniques

(2009) Deanna L. Pickel et al.   MACROMOLECULES

N-Trimethylsilyl Amines for Controlled Ring-Opening Polymerization of Amino AcidN-Carboxyanhydrides and Facile End Group Functionalization of Polypeptides

(2008) Hua Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY