Article
Clinical Neurology
David J. Kennaway
Summary: This study analyzed the saliva DLMO from 3579 participants and the plasma DLMO from 818 healthy controls. A reference range was established and the saliva DLMO was found to be earliest in children and latest around 20 years of age. Saliva DLMO was correlated with the MEQ score and showed a tendency toward morningness with age. Peak plasma melatonin levels varied within studies and age groups, with a small decline between 20 and 50 years and lowest levels after 70 years.
Article
Clinical Neurology
Linske de Bruijn, Danielle E. J. Starreveld, Michael Schaapveld, Flora E. van Leeuwen, Eveline M. A. Bleiker, Nina E. Berentzen
Summary: This study investigates the association between single-item chronotype and dim light melatonin onset, and finds a correlation between the two. The single-item chronotype questionnaire can serve as an effective alternative for assessing chronotype.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Clinical Neurology
Emily J. Ricketts, Helen J. Burgess, Gabrielle E. Montalbano, Meredith E. Coles, Joseph F. McGuire, Hardian Thamrin, Dana L. McMakin, James T. McCracken, Mary A. Carskadon, John Piacentini, Christopher S. Colwell
Summary: Individuals with TD commonly experience sleep disturbances. This study found that adults with TD had greater eveningness and sleep disturbances compared to healthy controls. Morning light therapy showed some benefits, including advances in DLMO phase and reductions in daytime sleepiness and anxiety. Further exploration of spectral tuning the photic environment as part of treatment for TD subjects is recommended.
JOURNAL OF NEUROLOGY
(2022)
Article
Psychiatry
Francy Cruz-Sanabria, Ugo Faraguna, Miriam Violi, Simone Bruno, Davide Gravina, Chiara Bonelli, Andrea Bazzani, Leonardo Massoni, Laura Musetti, Marly Simoncini, Paolo Frumento, Liliana Dell 'Osso, Claudia Carmassi
Summary: The present study evaluates the effect of exogenous melatonin on sleep and circadian parameters in patients with bipolar disorder and delayed sleep-wake phase disorder. Results indicate that personalized treatment with exogenous melatonin can modify self-reported chronotype, sleep onset time, and sleep efficiency and duration in patients with comorbid bipolar disorder and delayed sleep-wake phase disorder, suggesting potential efficacy in improving sleep patterns in this population.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Endocrinology & Metabolism
Giulia Zerbini, Eva C. Winnebeck, Martha Merrow
Summary: The study reveals that both season and weekly schedule impact the phase of entrainment and sleep in humans. In summer, the phase of entrainment is about 1 hour earlier compared to winter, with shorter sleep duration, particularly affecting individuals with later chronotypes. These findings suggest that the phase of entrainment is linked to midday or midnight rather than sunrise or sunset.
JOURNAL OF PINEAL RESEARCH
(2021)
Article
Multidisciplinary Sciences
C. Papatsimpa, L. J. M. Schlangen, K. C. H. J. Smolders, J-P M. G. Linnartz, Y. A. W. de Kort
Summary: Individuals differ in their timing of sleep and daytime activities, defining the "chronotype"; Spending time in relatively dim light conditions during the day leads to a later biological clock and increased interindividual differences in circadian phase; Increasing daytime illuminance results in a narrower distribution of sleep timing and circadian phase.
SCIENTIFIC REPORTS
(2021)
Review
Psychiatry
Niall M. McGowan, Kate E. A. Saunders
Summary: The recent evidence suggests that circadian rhythm disturbance is a common but unaddressed feature of BPD, which may worsen symptom severity. Preliminary studies suggest potential benefits of intervention, but development is limited.
CURRENT PSYCHIATRY REPORTS
(2021)
Article
Biology
Michal Mateusz Dermanowski, Arkadiusz Hejduk, Julita Kuczynska, Adam Wichniak, Agnieszka Urbanska, Pawel Mierzejewski
Summary: The study established a method for determining the concentration of melatonin (MELA) in plasma and saliva using liquid chromatography with tandem mass spectrometry (LC-MS/MS). The correlation between plasma and salivary MELA concentration was analyzed, and the dim light melatonin onset (DLMO) was evaluated using both matrices. The results showed a strong correlation between plasma and salivary MELA concentration, and the DLMO calculated based on both plasma and saliva profiles were also correlated.
CHRONOBIOLOGY INTERNATIONAL
(2022)
Article
Psychiatry
Delainey L. Wescott, Meredith L. Wallace, Brant P. Hasler, Alison M. Klevens, Peter L. Franzen, Martica H. Hall, Kathryn A. Roecklein
Summary: This study used data-driven analysis to characterize sleep and circadian disruptions in seasonal depression, and identified two distinct profiles. These findings can guide future interventions and improve treatment response.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Endocrinology & Metabolism
Mathilde Reyt, Michele Deantoni, Marion Baillet, Alexia Lesoinne, Sophie Laloux, Eric Lambot, Justine Demeuse, Chiara Calaprice, Caroline LeGoff, Fabienne Collette, Gilles Vandewalle, Pierre Maquet, Vincenzo Muto, Gregory Hammad, Christina Schmidt
Summary: This study found an association between daytime rest and 24-hour rest probability profiles, circadian timing, and neurobehavioral outcomes in healthy older adults. The results suggest that increasing daytime rest frequency is related to more fragmented nighttime rest and lower episodic memory performance.
JOURNAL OF PINEAL RESEARCH
(2022)
Article
Clinical Neurology
Peinan Zhao, Bronwyn S. Bedrick, Kristine E. Brown, Ronald McCarthy, Jessica E. Chubiz, Yo-El S. Ju, Nandini Raghuraman, Justin C. Fay, Emily S. Jungheim, Erik D. Herzog, Sarah K. England
Summary: This prospective cohort study compared sleep behavior before and during pregnancy in healthy women. The results indicated changes in sleep timing and quality throughout pregnancy, with the first trimester characterized by earlier sleep period start time, longer sleep duration, and poorer sleep quality than pre-pregnancy. Sleep quality temporarily improved in the second trimester, and sleep period start time returned to pre-pregnancy level by the third trimester.
Article
Biology
Garrett C. Hisler, Scott D. Rothenberger, Duncan B. Clark, Brant P. Hasler
Summary: Research has shown a 24-hour rhythm in alcohol craving, with sleep/circadian timing moderating this rhythm, as individuals with later sleep/circadian timing experience peak alcohol craving at a later time.
CHRONOBIOLOGY INTERNATIONAL
(2021)
Article
Clinical Neurology
Claudio Liguori, Matteo Spanetta, Mariana Fernandes, Fabio Placidi, Roberto Massa, Andrea Romigi, Francesca Izzi, Luca Mauro, Giulia Greco, Erica Frezza, Federica Cattaneo, Annalisa Rubino, Elio Clemente Agostoni, Lino Nobili, Nicola Biagio Mercuri, Valeria A. Sansone, Paola Proserpio
Summary: The study identifies abnormalities in sleep-wake rhythm in patients with myotonic dystrophy type 1 (DM1), including nocturnal sleep disturbances and reduced daytime motor activity, compared to healthy controls. These findings provide further evidence of sleep impairment and excessive daytime sleepiness in DM1 patients.
Article
Physiology
Jacopo A. Vitale, Stefano Borghi, Maria Francesca Piacentini, Giuseppe Banfi, Antonio La Torre
Summary: This study investigated the sleep characteristics of elite track-and-field athletes and found significant differences in sleep patterns between sexes and among different disciplines. Female athletes had better sleep quality, while sleep-hygiene strategies had a positive impact on athletes' sleep parameters.
INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE
(2023)
Article
Behavioral Sciences
Kyle P. De Young, Angeline R. Bottera, P. Evelyna Kambanis
Summary: Delayed eating rhythms, characterized by lack of morning hunger and elevated evening hunger, are associated with adverse health outcomes. This study investigated the role of light exposure timing and sleep quality in the link between sleep/wake time preferences and delayed diurnal appetite. Results showed that the timing of light exposure mediated the relationship between sleep/wake time preferences and evening hyperphagia, while sleep efficiency moderated the association between sleep/wake time preference and morning anorexia.