Lifespan Extension Via Dietary Restriction: Time to Reconsider the Evolutionary Mechanisms?

The hidden costs of dietary restriction: Implications for its evolutionary and mechanistic origins

(2020) Andrew W. McCracken et al.   Science Advances

Dietary restriction and insulin‐like signalling pathways as adaptive plasticity: A synthesis and re‐evaluation

(2019) J.C. Regan et al.   FUNCTIONAL ECOLOGY

Macronutrients and infection in fruit flies

(2019) Hue Dinh et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Diet modulates the relationship between immune gene expression and functional immune responses

(2019) Sheena C. Cotter et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Comparing ageing and the effects of diet supplementation in wild vs. captive antler flies, Protopiophila litigata

(2019) Brian S. Mautz et al.   JOURNAL OF ANIMAL ECOLOGY

Sex-specific transcriptomic responses to changes in the nutritional environment

(2019) M Florencia Camus et al.   eLife

Macronutrients modulate survival to infection and immunity in Drosophila

(2019) Fleur Ponton et al.   JOURNAL OF ANIMAL ECOLOGY

Nutrient-specific compensation for seasonal cold stress in a free-ranging temperate colobine monkey

(2018) Song-Tao Guo et al.   FUNCTIONAL ECOLOGY

The nutritional nexus: Linking niche, habitat variability and prey composition in a generalist marine predator

(2018) Gabriel E. Machovsky-Capuska et al.   JOURNAL OF ANIMAL ECOLOGY

Linking developmental diet to adult foraging choice inDrosophila melanogaster

(2018) Lucy Rebecca Davies et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Does Calorie Restriction in Primates Increase Lifespan? Revisiting Studies on Macaques (Macaca mulatta ) and Mouse Lemurs (Microcebus murinus )

(2018) Eric Le Bourg   BIOESSAYS

Reconciling nutritional geometry with classical dietary restriction: Effects of nutrient intake, not calories, on survival and reproduction

(2018) Joshua P. Moatt et al.   AGING CELL

Caloric restriction improves health and survival of rhesus monkeys

(2017) Julie A. Mattison et al.   Nature Communications

Body macronutrient composition is predicted by lipid and not protein content of the diet

(2017) Joshua P. Moatt et al.   Ecology and Evolution

Effects of macronutrient intake on the lifespan and fecundity of the marula fruit fly, Ceratitis cosyra (Tephritidae): Extreme lifespan in a host specialist

(2017) Kevin Malod et al.   Ecology and Evolution

The effect of dietary restriction on reproduction: a meta-analytic perspective

(2016) Joshua P. Moatt et al.   BMC EVOLUTIONARY BIOLOGY

Calories or protein? The effect of dietary restriction on lifespan in rodents is explained by calories alone

(2016) J.R. Speakman et al.   EXPERIMENTAL GERONTOLOGY

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

(2016) Sharon E. Mitchell et al.   Oncotarget

Differential effects of male nutrient balance on pre- and post-copulatory traits, and consequences for female reproduction in Drosophila melanogaster

(2016) Juliano Morimoto et al.   Scientific Reports

Sex-specific effects of protein and carbohydrate intake on reproduction but not lifespan inDrosophila melanogaster

(2015) Kim Jensen et al.   AGING CELL

The impact of low-protein high-carbohydrate diets on aging and lifespan

(2015) David G. Le Couteur et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Drosophila melanogaster larvae make nutritional choices that minimize developmental time

(2015) Marisa A. Rodrigues et al.   JOURNAL OF INSECT PHYSIOLOGY

Dietary protein:carbohydrate balance is a critical modulator of lifespan and reproduction in Drosophila melanogaster: A test using a chemically defined diet

(2015) Kwang Pum Lee   JOURNAL OF INSECT PHYSIOLOGY

Macronutrient balance, reproductive function, and lifespan in aging mice

(2015) Samantha M. Solon-Biet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

(2015) Sharon E. Mitchell et al.   Oncotarget

The effects of graded levels of calorie restriction: III. Impact of short term calorie and protein restriction on mean daily body temperature and torpor use in the C57BL/6 mouse

(2015) Sharon E. Mitchell et al.   Oncotarget

The Nutritional Geometry of Resource Scarcity: Effects of Lean Seasons and Habitat Disturbance on Nutrient Intakes and Balancing in Wild Sifakas

(2015) Mitchell T. Irwin et al.   PLoS One

Time of famine: Time to reproduce? (comment on DOI 10.1002/bies.201300165)

(2014) Éric Le Bourg   BIOESSAYS

Why do the well-fed appear to die young?

(2014) Margo I. Adler et al.   BIOESSAYS

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

(2014) Samantha M. Solon-Biet et al.   Cell Metabolism

Dietary restriction and the pursuit of effective mimetics

(2014) Colin Selman   PROCEEDINGS OF THE NUTRITION SOCIETY

Protein-poor diet reduces host-specific immune gene expression in Bombus terrestris

(2014) F. S. Brunner et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Towards a synthesis of frameworks in nutritional ecology: interacting effects of protein, carbohydrate and phosphorus on field cricket fitness

(2014) S. J. Harrison et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

(2014) Ricki J. Colman et al.   Nature Communications

Dietary restriction of rodents decreases aging rate without affecting initial mortality rate - a meta-analysis

(2013) Mirre J. P. Simons et al.   AGING CELL

High carbohydrate–low protein consumption maximizes Drosophila lifespan

(2013) Kimberley D. Bruce et al.   EXPERIMENTAL GERONTOLOGY

Dynamics of macronutrient self-medication and illness-induced anorexia in virally infected insects

(2013) Sonia Povey et al.   JOURNAL OF ANIMAL ECOLOGY

Comparative and meta-analytic insights into life extension via dietary restriction

(2012) Shinichi Nakagawa et al.   AGING CELL

Changes in diet, body mass and fatty acid composition during pre-hibernation in a subtropical bat in relation to NPY and AgRP expression

(2012) Eran Levin et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Cost of reproduction in the Queensland fruit fly: Y-model versus lethal protein hypothesis

(2012) B. G. Fanson et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Protein:carbohydrate ratios explain life span patterns found in Queensland fruit fly on diets varying in yeast:sugar ratios

(2011) Benjamin G. Fanson et al.   AGE

A longer and healthier life with TOR down-regulation: genetics and drugs: Figure 1

(2011) Ivana Bjedov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Genetic variation of dietary restriction and the effects of nutrient-free water and amino acid supplements on lifespan and fecundity of Drosophila

(2011) KENNETH B. DICK et al.   Genetics Research

Caloric restriction

(2011) John R. Speakman et al.   MOLECULAR ASPECTS OF MEDICINE

The plate half-full: Status of research on the mechanisms of dietary restriction in Drosophila melanogaster

(2010) Marc Tatar   EXPERIMENTAL GERONTOLOGY

Extending Healthy Life Span--From Yeast to Humans

(2010) L. Fontana et al.   SCIENCE

Nutrients, not caloric restriction, extend lifespan in Queensland fruit flies (Bactrocera tryoni)

(2009) Benjamin G. Fanson et al.   AGING CELL

Sex differences in nutrient-dependent reproductive ageing

(2009) Alexei A. Maklakov et al.   AGING CELL

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

(2009) Chen-Yu Liao et al.   AGING CELL

Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila

(2009) Richard C. Grandison et al.   NATURE

Longevityfertility trade-offs in the tephritid fruit fly,Anastrepha ludens, across dietary-restriction gradients

(2008) James R. Carey et al.   AGING CELL

Dietary composition specifies consumption, obesity, and lifespan inDrosophila melanogaster

(2008) Danielle A. Skorupa et al.   AGING CELL

Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan

(2008) Diane M. O'Brien et al.   CURRENT BIOLOGY

Sex-Specific Fitness Effects of Nutrient Intake on Reproduction and Lifespan

(2008) Alexei A. Maklakov et al.   CURRENT BIOLOGY

Can the protein costs of bacterial resistance be offset by altered feeding behaviour?

(2008) Sonia Povey et al.   JOURNAL OF ANIMAL ECOLOGY

Seasonal differences in the feeding ecology and behavior of male edible dormice (Glis glis)

(2008) Michaela M. Sailer et al.   MAMMALIAN BIOLOGY

Frequent summer nuptial flights of ants provide a primary food source for bats

(2008) Eran Levin et al.   NATURWISSENSCHAFTEN

Lifespan and reproduction in Drosophila: New insights from nutritional geometry

(2008) K. P. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The impact of dietary restriction, intermittent feeding and compensatory growth on reproductive investment and lifespan in a short-lived fish

(2008) C. L.W Inness et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES