期刊
AUTOPHAGY
卷 17, 期 8, 页码 1809-1827出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/15548627.2020.1798064
关键词
Agriculture; autophagy; cellular and tissue homeostasis; farm animals; physiology and animal production
类别
资金
- INRAE Animal Physiology and Livestock Systems Division [ACI_PHASE2018_autoPHAgoSomE]
Autophagy is a crucial cellular degradative process for maintaining cell homeostasis, but its role in species of agronomical interest remains largely unexplored.
Autophagy (a process of cellular self-eating) is a conserved cellular degradative process that plays important roles in maintaining homeostasis and preventing nutritional, metabolic, and infection-mediated stresses. Surprisingly, little attention has been paid to the role of this cellular function in species of agronomical interest, and the details of how autophagy functions in the development of phenotypes of agricultural interest remain largely unexplored. Here, we first provide a brief description of the main mechanisms involved in autophagy, then review our current knowledge regarding autophagy in species of agronomical interest, with particular attention to physiological functions supporting livestock animal production, and finally assess the potential of translating the acquired knowledge to improve animal development, growth and health in the context of growing social, economic and environmental challenges for agriculture.
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