ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)–Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm

Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm

(2020) Bo Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling

(2020) Yoshito Yamashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Introduction to the Compendium on Aortic Aneurysms

(2019) Raymundo Alain Quintana et al.   CIRCULATION RESEARCH

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation

(2019) Ploingarm Petsophonsakul et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cofilin drives rapid turnover and fluidization of entangled F-actin

(2019) Patrick M. McCall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired smooth muscle cell contractility as a novel concept of abdominal aortic aneurysm pathophysiology

(2019) Natalija Bogunovic et al.   Scientific Reports

Comparative analysis of small RNAs released by the filarial nematode Litomosoides sigmodontis in vitro and in vivo

(2019) Juan F. Quintana et al.   PLoS Neglected Tropical Diseases

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

(2019) Sayantan Jana et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies—Statement From ATVB CouncilHighlights

(2018) Peggy Robinet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation

(2018) Xiaoyuan Yang et al.   CARDIOVASCULAR RESEARCH

Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic AneurysmNovelty and Significance

(2018) Mengcheng Shen et al.   CIRCULATION RESEARCH

Structural basis for cofilin binding and actin filament disassembly

(2018) Kotaro Tanaka et al.   Nature Communications

Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans

(2018) Yoshito Yamashiro et al.   CIRCULATION RESEARCH

Thrombospondin 1 Is Increased in the Aorta and Plasma of Patients With Acute Aortic Dissection

(2018) Tao Zeng et al.   CANADIAN JOURNAL OF CARDIOLOGY

PI3Kα-regulated gelsolin activity is a critical determinant of cardiac cytoskeletal remodeling and heart disease

(2018) Vaibhav B. Patel et al.   Nature Communications

Abdominal aortic aneurysms

(2018) Natzi Sakalihasan et al.   Nature Reviews Disease Primers

Vascular ADAM17 (a Disintegrin and Metalloproteinase Domain 17) Is Required for Angiotensin II/β-Aminopropionitrile–Induced Abdominal Aortic AneurysmNovelty and Significance

(2017) Tatsuo Kawai et al.   HYPERTENSION

Loss of smooth muscle cell disintegrin and metalloproteinase 17 transiently suppresses angiotensin II-induced hypertension and end-organ damage

(2017) Mengcheng Shen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Challenges and opportunities in limiting abdominal aortic aneurysm growth

(2017) Jonathan Golledge et al.   JOURNAL OF VASCULAR SURGERY

ADAMTS-1 in abdominal aortic aneurysm

(2017) Emina Vorkapic et al.   PLoS One

Critical Role of ADAMTS-4 in the Development of Sporadic Aortic Aneurysm and Dissection in Mice

(2017) Pingping Ren et al.   Scientific Reports

Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm

(2017) Tong Jiao et al.   Biomed Research International

Inflammatory Cell Phenotypes in AAAsSignificance

(2015) Matthew A. Dale et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Many Faces of Matrix Metalloproteinases in Aortic Aneurysms: Figure.

(2015) Hong Lu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Divergent Roles of Matrix Metalloproteinase 2 in Pathogenesis of Thoracic Aortic AneurysmSignificance

(2015) Mengcheng Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thrombospondin-1 (TSP1) Contributes to the Development of Vascular Inflammation by Regulating Monocytic Cell Motility in Mouse Models of Abdominal Aortic AneurysmNovelty and Significance

(2015) Zhenjie Liu et al.   CIRCULATION RESEARCH

The Role of Endothelial Dysfunction in Aortic Aneurysms

(2015) Gerasimos Siasos et al.   CURRENT PHARMACEUTICAL DESIGN

Angiotensin II and Abdominal Aortic Aneurysms: An update

(2015) Jing Liu et al.   CURRENT PHARMACEUTICAL DESIGN

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family

(2015) Richard Kelwick et al.   GENOME BIOLOGY

ADAMTS-1 and ADAMTS-4 Levels Are Elevated in Thoracic Aortic Aneurysms and Dissections

(2012) Pingping Ren et al.   ANNALS OF THORACIC SURGERY

A Disintegrin and Metalloproteinase 15 Contributes to Atherosclerosis by Mediating Endothelial Barrier Dysfunction via Src Family Kinase Activity

(2012) Chongxiu Sun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Current prevalence of abdominal aortic aneurysm in 70-year-old women

(2012) S. Svensjö et al.   BRITISH JOURNAL OF SURGERY

Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylation

(2012) Kensaku Mizuno   CELLULAR SIGNALLING

Loss ofTimp3Gene Leads to Abdominal Aortic Aneurysm Formation in Response to Angiotensin II

(2012) Ratnadeep Basu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Thrombospondins

(2011) J. C. Adams et al.   Cold Spring Harbor Perspectives in Biology

Atherosclerosis and Abdominal Aortic Aneurysm

(2010) Jonathan Golledge et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Atherosclerosis in Abdominal Aortic Aneurysms: A Causal Event or a Process Running in Parallel? The Tromsø Study

(2010) Stein Harald Johnsen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling

(2010) C. Sun et al.   CARDIOVASCULAR RESEARCH

Thrombospondin and Apoptosis: Molecular Mechanisms and Use for Design of Complementation Treatments

(2008) Y. Mirochnik et al.   CURRENT DRUG TARGETS

An Adam15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization

(2008) Bing Xie et al.   FASEB JOURNAL

ADAM-15: a metalloprotease that mediates inflammation

(2007) Laetitia Charrier-Hisamuddin et al.   FASEB JOURNAL