Article
Virology
Roman B. Bayandin, Marat T. Makenov, Sanaba Boumbaly, Olga A. Stukolova, Anastasia V. Gladysheva, Andrey V. Shipovalov, Maksim O. Skarnovich, Ousmane Camara, Aboubacar Hady Toure, Victor A. Svyatchenko, Alexander N. Shvalov, Vladimir A. Ternovoi, Mamadou Y. Boiro, Alexander P. Agafonov, Lyudmila S. Karan
Summary: This article presents a case report of Zika fever in a pregnant woman from Guinea in 2018. The Zika virus isolated from the patient belonged to the African lineage, specifically the Nigerian sublineage. In addition, serological screening revealed a varying seroprevalence of Zika virus infection among febrile patients in Faranah, ranging from 5.6% to 17.1%.
Article
Microbiology
Maria Vittoria Mancini, Rapeepat Tandavanitj, Thomas H. H. Ant, Shivan M. M. Murdochy, Daniel D. D. Gingell, Chayanee Setthapramote, Piyatida Natsrita, Alain Kohl, Steven P. P. Sinkins, Arvind H. H. Patel, Giuditta De Lorenzo
Summary: In this study, a promising Zika virus vaccine candidate was validated in a mosquito-mouse transmission model, showing its ability to protect animals from the disease and reduce virus transmission. The study also revealed the enhancement of viral infection and spread through mosquito bites.
Review
Microbiology
Sineewanlaya Wichit, Nuttamonpat Gumpangseth, Rodolphe Hamel, Sakda Yainoy, Siwaret Arikit, Chuchard Punsawad, Dorothee Misse
Summary: Chikungunya and Zika viruses have globally re-emerged over the past 60 years and there is currently no specific antiviral treatment. Understanding viral-host interactions is crucial for developing targeted therapeutics, but limited information is available in this area at present.
Article
Microbiology
Cassandra Koh, Annabelle Henrion-Lacritick, Lionel Frangeul, Maria-Carla Saleh
Summary: Palm Creek virus can interfere with mosquito-borne flavivirus replication in Culex mosquitoes, but does not have an effect on the transmission of Zika and chikungunya viruses in Aedes mosquitoes. Additionally, the interference mechanism is unlikely to be through RNA interference.
Article
Microbiology
Bachirou Tinto, Didier Patinde Alexandre Kabore, Dramane Kania, Therese Samdapawinde Kagone, Alice Kiba-Koumare, Laura Pinceloup, Guillaume Thaurignac, Philippe Van de Perre, Roch Kounbobr Dabire, Thierry Baldet, Serafin Guitierrez, Patricia Gil, Ahidjo Ayouba, Sara Salinas, Yannick Simonin
Summary: Based on a study of blood donor samples in Burkina Faso, the seroprevalence of Zika virus and dengue virus is high in the region, especially for dengue virus. Although molecular evidence of Zika virus circulation could not be demonstrated, this research suggests the need to strengthen arbovirus surveillance in Burkina Faso and further investigate the epidemiology of these viruses.
Article
Cell Biology
Hsin-Wei Wang, Hsing-Han Li, Shih-Cheng Wu, Cheng-Kang Tang, Hui-Ying Yu, Ya-Chen Chang, Pei-Shan Sung, Wei-Liang Liu, Matthew P. Su, Guann-Yi Yu, Li-Rung Huang, Chun-Hong Chen, Shie-Liang Hsieh
Summary: In this study, researchers found that C-type lectin 5A (CLEC5A) plays a crucial role in testicular damage caused by Zika virus infection. CLEC5A enables leukocytes to infiltrate past the blood-testis barrier and induce damage to testicular and epididymal tissues, and it is associated with inflammatory responses. Therefore, CLEC5A may be a potential therapeutic target for the prevention of male reproductive organ injuries in Zika virus patients.
JOURNAL OF BIOMEDICAL SCIENCE
(2023)
Review
Medicine, General & Internal
Lukas Wilkman, Clas Ahlm, Magnus Evander, Olivia Wesula Lwande
Summary: Five endemic mosquito-borne viruses in Fennoscandia have significant impact on human health, but their incidence remains unknown due to underdiagnosing and lack of surveillance. The complex transmission and lack of clear case definition criteria make prevention and diagnosis of Fennoscandian moboviruses challenging, leading to potential misdiagnosis. Some infections have long-term effects such as malaise, rash, and joint pain. Research on mobovirus diseases is mainly focused on a few pathogens, neglecting many others. This review aims to summarize current medically relevant knowledge of moboviruses in Fennoscandia while highlighting unknown and overlooked aspects.
FRONTIERS IN MEDICINE
(2023)
Article
Cell Biology
Judith Mary Reyes Ballista, Kerri L. Miazgowicz, Marissa D. Acciani, Ariana R. Jimenez, Ryan S. Belloli, Katherine E. Havranek, Melinda A. Brindley
Summary: Chikungunya virus (CHIKV) causes chikungunya fever and currently there are no licensed vaccines or antivirals available. Therefore, preventing viral attachment to host cells is a potential intervention strategy.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Virology
Erika Oliveira Gomes, Livia Sacchetto, Mauricio Teixeira, Barbara Aparecida Chaves, Adam Hendy, Claudia Mendonca, Izabele Guimaraes, Ramon Linhares, Daniela Brito, Danielle Valerio, Jady Shayenne Mota Cordeiro, Alexandre Vilhena Silva Neto, Vanderson Souza Sampaio, Vera Margarete Scarpassa, Michaela Buenemann, Nikos Vasilakis, Djane Clarys Baia-da-Silva, Mauricio Lacerda Nogueira, Maria Paula Gomes Mourao, Marcus Vinicius Guimaraes Lacerda
Summary: This study investigated the infection of Zika virus (ZIKV) in mosquito species sampled from urban forest fragments in Manaus, Brazilian Amazon. The results demonstrated the first-ever evidence of Ae. albopictus naturally infected with ZIKV in the Amazon region.
Article
Microbiology
Fengjuan Tian, Jimin He, Shanlin Shang, Zhongyan Chen, Yumei Tang, Man Lu, Changzhi Huang, Xiaofang Guo, Yigang Tong
Summary: Mosquitoes play a significant role in spreading complex pathogens, particularly through their feeding habits on mammalian blood. Surveillance of mosquito-borne viruses is crucial in preventing and controlling arboviral diseases. This study focused on the neighborhoods along the Sino-Vietnam border in Yunnan Province, China, and identified various mosquito species and mosquito-borne viruses, including some previously unreported viruses in China. These findings emphasize the importance of viral surveillance and prevention measures in border areas to prevent future outbreaks.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Multidisciplinary Sciences
Daniella A. Lefteri, Steven R. Bryden, Marieke Pingen, Sandra Terry, Emily F. Beswick, Georgi Georgiev, Marleen Van der Laan, Valeria Mastrullo, Paola Campagnolo, Robert Waterhouse, Margus Varjak, Andres Merits, Rennos Fragkoudis, Stephen Griffin, Kave Shams, Emilie Pondeville, Clive S. McKimmie
Summary: Viruses transmitted by Aedes mosquitoes are a significant global cause of disease. The enhancement of virus infection by mosquito saliva is mediated by a gene product called sialokinin, which rapidly reduces endothelial barrier integrity. This mechanism is absent in Anopheles mosquitoes, explaining their incompetence in transmitting arthropod-borne viruses. Therapeutic strategies targeting sialokinin have potential in reducing disease severity following infection with Aedes-mosquito-borne viruses.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Microbiology
Brent Edwards, Elodie Ghedin, Denis Voronin
Summary: Wolbachia suppresses Zika virus replication by altering cholesterol biosynthesis and depleting lipid droplets in host cells, resulting in decreased viral titers. This study provides insights into the mechanism behind Wolbachia-induced interference of arbovirus replication and could contribute to the development of strategies to control arbovirus pathogens.
MICROBIOLOGY SPECTRUM
(2023)
Article
Clinical Neurology
Sonja E. Leonhard, Susan Halstead, Suzannah B. Lant, Maria de Fatima Pessoa Militao de Albuquerque, Carlos Alexandre Antunes de Brito, Livia Brito Bezerra de Albuquerque, Mark A. Ellul, Rafael Freitas de Oliveira Franca, Dawn Gourlay, Michael J. Griffiths, Adelia Maria de Miranda Henriques-Souza, Maria I. de Morais Machado, Raquel Medialdea-Carrera, Ravi Mehta, Roberta da Paz Melo, Solange D. Mesquita, Alvaro J. P. Moreira, Lindomar J. Pena, Marcela Lopes Santos, Lance Turtle, Tom Solomon, Hugh J. Willison, Bart C. Jacobs, Maria L. Brito Ferreira
Summary: This study investigated the clinical phenotype and antibody signature of GBS patients following Zika virus and chikungunya virus outbreaks in Northeast Brazil. The majority of patients had evidence of recent arbovirus infection, with longer hospital stays observed in those infected with both Zika and chikungunya viruses.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Immunology
Ruklanthi de Alwis, Raphael M. Zellweger, Edmond Chua, Lin-Fa Wang, Tanu Chawla, October M. Sessions, Damien Marlier, John E. Connolly, Veronika von Messling, Danielle E. Anderson
Summary: The differences in Asian sub-lineages of Zika virus may partially explain the range of disease severity observed. Neurotropic sub-lineages are associated with higher levels of systemic inflammation and cell recruitment in adults. Anti-inflammatory therapeutics may be explored as early treatment to prevent adult Zika-associated disease.
EMERGING MICROBES & INFECTIONS
(2021)
Article
Microbiology
Rebecca A. Zimler, Barry W. Alto
Summary: The study revealed that both Aedes aegypti and Ae. albopictus in Florida have a high competence for Zika virus infection, which may contribute to high rates of Zika virus transmission in the Florida populations. The extrinsic incubation period (EIP) for Zika virus was found to be shorter in Ae. albopictus compared to Ae. aegypti.
Article
Pediatrics
Char Leung, Ka-Wah Khong, Kwok-Hung Chan, Marcus Vinicius Guimaraes Lacerda, Carlos Henrique Michiles Frank
Summary: This study investigates the clinical features of pediatric patients with SARS-CoV-2 before and after the emergence of the P.1 variant. During the P.1-dominant period, infected patients had a lower case-fatality rate but a lower prevalence of fever and lower respiratory tract symptoms, and a higher prevalence of neurological symptoms.
PEDIATRIC RESEARCH
(2023)
Article
Virology
Adam Hendy, Nelson Ferreira Fe, Danielle Valerio, Eduardo Hernandez-Acosta, Barbara A. Chaves, Luis Felipe Alho da Silva, Rosa Amelia Goncalves Santana, Andreia da Costa Paz, Matheus Mickael Mota Soares, Flamarion Prado Assuncao, Jose Tenacol Andes, Chiara Andolina, Vera Margarete Scarpassa, Marcus Vinicius Guimaraes de Lacerda, Kathryn A. Hanley, Nikos Vasilakis
Summary: We described the techniques of installment hatching, artificial blood feeding, and forced-mating, which allowed us to produce small numbers of F-3 generation Hg. janthinomys eggs for the first time. Although we were unable to maintain a laboratory colony of Hg. janthinomys past the F-3 generation, our methods provide a foundation for experimental transmission studies with this species in a laboratory setting.
Article
Infectious Diseases
Adam Hendy, Eduardo Hernandez-Acosta, Danielle Valerio, Nelson Ferreira Fe, Claudia Reis Mendonca, Edson Rodrigues Costa, Eloane Silva de Andrade, Jose Tenacol Andes Junior, Flamarion Prado Assuncao, Vera Margarete Scarpassa, Marcus Vinicius Guimaraes de Lacerda, Michaela Buenemann, Nikos Vasilakis, Kathryn A. Hanley
Summary: By studying mosquito community composition and environmental variables at different distances from the edge of a rainforest reserve in the central Brazilian Amazon, we found that species richness and diversity were higher closer to the forest edge and decreased further away. The composition of the mosquito community also changed significantly within the first 500 meters. Environmental variables associated with the occurrence of key mosquito taxa were identified.
PLOS NEGLECTED TROPICAL DISEASES
(2023)
Article
Food Science & Technology
Felipe Murta, Eleanor Strand, Altair Seabra de Farias, Felipe Rocha, Alicia Cacau Santos, Evellyn Antonieta Tome Rondon, Ana Paula Silva de Oliveira, Hiran Satiro Souza da Gama, Yasmim Vieira Rocha, Gisele dos Santos Rocha, Mena Ferreira, Vinicius Azevedo Machado, Marcus Lacerda, Manuela Pucca, Felipe Cerni, Joao Ricardo Nickenig Vissoci, Anna Tupetz, Charles J. Gerardo, Ana Maria Moura-da-Silva, Fan Hui Wen, Jacqueline Sachett, Wuelton Monteiro
Summary: Research has found that snakebite envenomations are a significant problem for indigenous populations in the Brazilian Amazon. However, little research has been conducted on how indigenous peoples access and utilize the health system for snakebite treatment. The study suggests that decentralizing antivenom to local health units and providing additional resources can improve patient care, while further research is needed on preparing healthcare professionals to work in intercultural contexts.
Article
Immunology
Camila Fabbri, Glenda Quaresma Ramos, Djane Clarys Baia-da-Silva, Alexandre Oliveira Trindade, Luis Carlos Salazar-Alvarez, Juliana Costa Ferreira Neves, Ivanildes dos Santos Bastos, Allyson Guimaraes Costa, Marcus Vinicius Guimaraes Lacerda, Wuelton Marcelo Monteiro, Fabio Trindade Maranhao Costa, Stefanie Costa Pinto Lopes
Summary: This study evaluated the potential of methylene blue (MB) against the asexual and sexual forms of Plasmodium vivax. The results showed that MB had high efficacy against the asexual stages and demonstrated some inhibition in the sexual forms. These findings suggest that MB may be a potential drug for the treatment of vivax malaria.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Immunology
Luis Carlos Salazar Alvarez, Vanessa Carneiro Barbosa, Omaira Vera Lizcano, Djane Clarys Baia da Silva, Rosa Amelia Goncalves Santana, Camila Fabbri, Paulo Filemon Paoluci Pimenta, Wuelton Marcelo Monteiro, Letusa Albrecht, Marcus Vinicius Guimaraes de Lacerda, Fabio Trindade Maranhao Costa, Stefanie Costa Pinto Lopes
Summary: Plasmodium vivax is the most common type of malaria outside sub-Saharan Africa, and its ability to adhere to cells, form rosettes, and develop in the liver can impact treatment and disease control. In this study, we used ex vivo methods to evaluate the rosetting capacity of P. vivax gametocytes and investigated its effect on infection in the mosquito vector Anopheles aquasalis. We found a high frequency of cytoadhesive phenomena and a positive correlation between rosetting and infection rate and intensity in the mosquito. Disruption of rosette formation resulted in lower infection rates and intensities.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Infectious Diseases
Giselle da Silva Duarte, Alexandra Jones, Luciano Pamplona de Goes Cavalcanti, Moacyr Jesus Barreto de Melo Rego, Guilherme Ribeiro, Rosemary Boyton, Dhelio Batista Pereira, Julio Henrique Rosa Croda, Fabio Trindade Maranhao Costa, Angela Pinto Duarte, Marcia Edilaine Lopes Consolaro, Rodrigo Guerino Stabeli, Fabio Juliano Negrao, Jose Luiz Proenca-Modena, Juan Miguel Villalobos-Salcedo, Geraldo da Rocha Castelar Pinheiro, Amanda Pinheiro de Barros Albuquerque, Francisca Kalline de Almeida Barreto, Jose Moreira, Idalina Cristina Ferrari, Patricia Martinez Evora, Vania Ramos Sela da Silva, Marcus Vinicius Guimaraes Lacerda, Daniel Altmann, REPLICK Network, Andre M. Siqueira
Summary: This study is the largest evaluation of the long-term sequelae of individuals infected with CHIKV in the Brazilian population, focusing on musculoskeletal manifestations, mental health, quality of life, and chronic pain. The aim of this study is to better understand the disease burden and costs associated with CHIKV infection and to inform therapeutic guidelines.
BMC INFECTIOUS DISEASES
(2023)
Article
Virology
Erika Oliveira Gomes, Livia Sacchetto, Mauricio Teixeira, Barbara Aparecida Chaves, Adam Hendy, Claudia Mendonca, Izabele Guimaraes, Ramon Linhares, Daniela Brito, Danielle Valerio, Jady Shayenne Mota Cordeiro, Alexandre Vilhena Silva Neto, Vanderson Souza Sampaio, Vera Margarete Scarpassa, Michaela Buenemann, Nikos Vasilakis, Djane Clarys Baia-da-Silva, Mauricio Lacerda Nogueira, Maria Paula Gomes Mourao, Marcus Vinicius Guimaraes Lacerda
Summary: This study investigated the infection of Zika virus (ZIKV) in mosquito species sampled from urban forest fragments in Manaus, Brazilian Amazon. The results demonstrated the first-ever evidence of Ae. albopictus naturally infected with ZIKV in the Amazon region.
Article
Biochemistry & Molecular Biology
Cesar Camilo Prado Sepulveda, Rodrigo Maciel Alencar, Rosa Amelia Santana, Igor Belem de Souza, Gigliola Mayra Ayres D'Elia, Raquel Soares Maia Godoy, Ana Paula Duarte, Stefanie Costa Pinto Lopes, Marcus Vinicius Guimaraes de Lacerda, Wuelton Marcelo Monteiro, Rafael Nacif-Pimenta, Nagila Francinete Costa Secundino, Leonardo Barbosa Koerich, Paulo Filemon Paolucci Pimenta
Summary: Anophelines, the vectors of malaria, were studied to understand their immune response genes and explore potential methods for controlling malaria. The Anopheles aquasalis genome provided new information about the evolution of immune response genes. The study revealed differences in pathogen recognition and modulation genes, while genes related to the expression of effectors and reactive oxygen species production were more conserved. These findings are important for understanding and controlling malaria in the New World.
Article
Health Care Sciences & Services
Claudia Cristina de Aguiar Pereira, Thiago Silva Torres, Paula Mendes Luz, Brenda Hoagland, Alessandro Farias, Jose David Urbaez Brito, Marcus Vinicius Guimaraes Lacerda, Daila Alena Raenck Silva, Marcos Benedetti, Maria Cristina Pimenta, Beatriz Grinsztejn, Valdilea Goncalves Veloso
Summary: Men who have sex with men (MSM) and transgender women (TGW) in Latin America are disproportionately affected by HIV infection. This study assessed pre-exposure prophylaxis (PrEP) preferences among sexual and gender minorities (SGM) and identified important attributes and levels for PrEP uptake and adherence. The results showed that higher HIV protection, no side effects, and presentation (injectable or implant) were the most important factors in PrEP preferences.
LANCET REGIONAL HEALTH-AMERICAS
(2023)
Article
Parasitology
Veronica Diniz Rocha, Larissa W. Brasil, Erika de Oliveira Gomes, Ricardo Khouri, Gilcivaldo de Jesus Ferreira, Beatriz Vasconcelos, Marcela de Sa Gouveia, Thais Souza Santos, Mitermayer G. Reis, Marcus Vinicius Guimaraes Lacerda
Summary: Coinfection of severe malaria and COVID-19 was observed in a non-malaria-endemic region, posing challenges in differential diagnosis. A female patient, aged 44, presented with malaise, fever, hypotension, jaundice, and enlarged liver and spleen. COVID-19 coinfection was confirmed by positive reverse transcription-quantitative PCR results, while Plasmodium vivax infection was confirmed by positive rapid tests, microscopy, and quantitative PCR.
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
(2023)
Article
Infectious Diseases
Raimunda Sandra Pacheco Souza, Monique F. dos Reis, Luiz Carlos de Lima Ferreira, Manuela C. Morais, Antonio Kassio S. Lima, Laila Rowena Albuquerque Barbosa, Gisely Cardoso de Melo, Marcus Vinicius Guimaraes de Lacerda
Summary: The study successfully standardized a method for extracting P. vivax DNA from splenic histological slices, with positive results in the control sample. However, all 200 samples tested were negative for Plasmodium sp. DNA but positive for human DNA.
Article
Parasitology
Gabriela Martinez Moura Tavares, Hannar Angelica de Melo Alverga, Estela Moraes Felix, Giovana de Oliveira Dichman, Gabriel Monteiro Pinheiro, Yara Juliano, Priscila Paruci, Dennis Minoru Fujita, Lucas Melo Neves, Marina Tiemi Shio, Luiz Henrique da Silva Nali
Summary: This study investigated the frequency of N. gonorrhoeae infection in women in a poor area of São Paulo and found that most of the strains detected showed resistance to one or more antimicrobials.
Article
Parasitology
Qian Yao, Ying-Ying Fan, Shuang Huang, Gui-Rong Hu, Jun-Ke Song, Xin Yang, Guang-Hui Zhao
Summary: This study found that the expression of miR-4521 was upregulated during C. parvum infection, and this upregulation was related to the TLR/NF-kappa B signal pathway. Additionally, miR-4521 promoted the propagation of C. parvum in HCT-8 cells by regulating BCL2-mediated cell apoptosis through targeting foxm1.
Article
Parasitology
Cho Naing, Maxine A. Whittaker, Wong Siew Tung, Htar Aung, Joon Wah Mak
Summary: This study aimed to estimate the prevalence of zoonotic brugian filariasis in animals and compare it with the prevalence in humans in the same area. The findings suggest that cats, dogs, and leaf-eating monkeys may serve as potential reservoirs for human brugian filariasis.
Review
Parasitology
Raissa Nogueira de Brito, Susan Tanner, Julie Velasquez Runk, Juliana Hoyos
Summary: This study conducted a scoping review to identify major research themes and knowledge gaps in the social science literature on leishmaniases or Chagas disease. The findings showed that research in this field mainly focuses on the sociocultural, economic, historical, and political dimensions of the diseases. Future research should pay more attention to how social institutions and economic factors shape disease education, control measures, healthcare access, and quality of life of affected individuals.
Article
Parasitology
Minghao Zheng, Mengyao Zhang, Hao Li, Shipo Wu, Yuee Zhao, Jinlong Zhang, Yunyue Zhou, Mohamed Boie Jalloh, Kun Zhang, Lina Chen, Zhiqiang Mi, Yong Cui, Lihua Hou
Summary: Rapid and convenient detection of Plasmodium falciparum, the deadliest malaria parasite in Africa, is crucial for malaria eradication efforts in medical resource-limited settings. A CRISPR-based diagnostic method that can detect P. falciparum without nucleic acid extraction was developed and showed high sensitivity and consistency with qPCR test. It can also detect artemisinin-resistant strains and other laboratory-cultured strains. This method has great potential for clinical testing and large-scale community screening in Africa and other regions.
Article
Parasitology
Fabian Correa-Morales, Cassandra Gonzalez-Acosta, David Ibarra-Ojeda, Miguel Moreno-Garcia
Summary: Since 2002, West Nile Virus (WNV) has been reported in 18 states in Mexico. This paper discusses the proposed hypotheses for the absence of WNV outbreaks in Latin America and provides a context-specific explanation for Mexico.
Article
Parasitology
Umberto Molini, Lauren M. Coetzee, Vernon Christians, Maria Y. Hemberger, Bernard Chiwome, Maria Amukwaya, Siegfried Khaiseb, Giovanni Cattoli, William G. Dundon, Giovanni Franzo
Summary: Porcine circovirus 3 (PCV-3) has been reported globally since its first identification in 2015. Limited data on PCV-3 in Africa led to a study in Namibia, which found a high prevalence of PCV-3 in backyard piggeries, but not in commercial farms with higher biosecurity measures. The source of viral introduction and factors such as semen importation, feeding backyard pigs with human food waste, pig exchanges, and wildlife movements may be involved in the dispersal of PCV-3 within Namibia. Further studies are needed to understand the epidemiology and impact of PCV-3 on pig productivity and wildlife health.
Article
Parasitology
Chutchai Piewbang, Panida Poonsin, Pattiya Lohavicharn, Panitnan Punyathi, Sawang Kesdangsakonwut, Tanit Kasantikul, Somporn Techangamsuwan
Summary: This study provides insights into the pathology of natural SARS-CoV-2 infection in dogs, revealing severe damage to the lungs and involvement of multiple organs. The findings suggest the potential utility of dogs as a model for studying SARS-CoV-2 infection in humans, highlighting the need for further investigation.
Article
Parasitology
Julian Avila-Jimenez, Juan David Gutierrez, Mariano Altamiranda-Saavedra
Summary: Leishmaniasis is a parasitic disease transmitted to humans by sandfly vectors and vertebrate hosts. This study used ecological niche modeling to investigate the potential distribution of host and vector species associated with cutaneous leishmaniasis transmission, revealing different distribution patterns under varying climatic conditions.
Article
Parasitology
Luis A. Gomez-Puerta, Juan Olazabal, Santiago Paredes, Juan Lopez, Miguel Anampa, Angelica Mondragon, Ana Vargas-Calla, Hugo Castillo
Summary: This study reports the first detection of Candidatus M. haemolamae infection in vicunas from the Pampa Galeras National Reserve in Peru, using molecular diagnosis. Tick-infested vicunas had a higher likelihood of being infected with Candidatus M. haemolamae compared to tick-free vicunas. Gender and age were not associated with infection.
Article
Parasitology
Berlin Londono-Renteria, Zakaria Seidu, Helena Lamptey, Michael F. Ofori, Lars Hviid, Mary Lopez-Perez
Summary: Heterozygous carriers of HbAS and HbAC have a reduced risk of severe malaria, but not immunity against Plasmodium falciparum infection. Antibody levels against gSG6-P1 peptide in Anopheles mosquito saliva can serve as a serological biomarker for exposure to Plasmodium infection. This study highlights the importance of studying the role of hemoglobinopathies in malaria transmission for improving control interventions.
Article
Parasitology
Imane Belbacha, Meryem El Azzouzi, Rajae Bensghir, Kamal Filali Marhoum, Khadija Hajjout, El Mir Elharti, Khalid Sadki, Hicham Oumzil
Summary: This study investigates the association of three SNPs in the APOBEC3G gene with disease outcomes in Moroccan HIV-1 infected patients. The rs2294367 CG genotype is strongly associated with protection against HIV-1 infection, particularly in older individuals.
Article
Parasitology
Tan Luong, Do Kien Tran, Anh Hung Pham, Thi Thu-Ha Hoang, Van Khang Pham, Quang Thai Pham, Thi Mai Hung Tran, Minh Hoa Luong, Thanh Long Pham, Jason K. Blackburn
Summary: This study examined the epidemiology of anthrax in Lai Chau province, Vietnam, using historical data. Spatial clusters of human and livestock anthrax were identified, and the characteristics of the disease were described. The study found that there were distinct differences between the high-risk areas for human and livestock anthrax, and most human cases occurred during specific seasons. Additionally, the decrease in livestock anthrax vaccine coverage was associated with an increase in disease incidence.
Article
Parasitology
Jin-tao Chen, Jian-bo Zhan, Ming-chao Zhu, Kai-ji Li, Man-qing Liu, Bin Hu, Kun Cai, Hai-rong Xiong, Shu-liang Chen, Wei-long Tan, Liang-jun Chen, Wei Hou
Summary: This study investigated the prevalence and variation of orthohantavirus in rodents and humans in Hubei province, China. It identified the diversity of orthohantaviruses circulating in the region, with the HV004-like subtype being the main genotype in rodents and patients. This highlights the importance of continued attention and research on orthohantaviruses, especially newly identified strains.