The QTc-Polygenic Risk Score (QTc-PRS) and its Contribution to Type 1, Type 2, and Type 3 Long QT Syndrome in Probands and Genotype-Positive Family Members

An International, Multicentered, Evidence-Based Reappraisal of Genes Reported to Cause Congenital Long QT Syndrome

(2020) Arnon Adler et al.   CIRCULATION

Variant Frequency and Clinical Phenotype Call Into Question the Nature of Minor, Nonsyndromic Long-QT Syndrome–Susceptibility Gene-Disease Associations

(2020) John R. Giudicessi et al.   CIRCULATION

Common Genetic Variation and Breast Cancer Risk—Past, Present, and Future

(2018) Jenna Lilyquist et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Physiological genomics identifies genetic modifiers of long QT syndrome type 2 severity

(2018) Sam Chai et al.   JOURNAL OF CLINICAL INVESTIGATION

The genetic architecture of long QT syndrome: A critical reappraisal

(2018) John R. Giudicessi et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Polygenic risk score predicts prevalence of cardiovascular disease in patients with familial hypercholesterolemia

(2017) Martine Paquette et al.   Journal of Clinical Lipidology

Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk EstimatesCLINICAL PERSPECTIVE

(2016) Iftikhar J. Kullo et al.   CIRCULATION

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2CLINICAL PERSPECTIVE

(2015) Iris C.R.M. Kolder et al.   Circulation-Cardiovascular Genetics

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2CLINICAL PERSPECTIVE

(2015) Iris C.R.M. Kolder et al.   Circulation-Cardiovascular Genetics

Long-QT Syndrome

(2012) Peter J. Schwartz et al.   Circulation-Arrhythmia and Electrophysiology

Determinants of incomplete penetrance and variable expressivity in heritable cardiac arrhythmia syndromes

(2012) John R. Giudicessi et al.   Translational Research

Clinical Correlates and Heritability of QT Interval Duration in Blacks

(2009) Ermeg L. Akylbekova et al.   Circulation-Arrhythmia and Electrophysiology

Genetic variation in NOS1AP is associated with sudden cardiac death: evidence from the Rotterdam Study

(2009) M. Eijgelsheim et al.   HUMAN MOLECULAR GENETICS

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

(2009) Arne Pfeufer et al.   NATURE GENETICS

Association of NOS1AP Genetic Variants With QT Interval Duration in Families From the Diabetes Heart Study

(2008) A. B. Lehtinen et al.   DIABETES