Recent Advances in Understanding the Protein Corona of Nanoparticles and in the Formulation of “Stealthy” Nanomaterials

Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

(2019) Qing Xia et al.   Acta Pharmaceutica Sinica B

Stealth Iron Oxide Nanoparticles for Organotropic Drug Targeting

(2019) Massimiliano Magro et al.   BIOMACROMOLECULES

Liposome protein corona characterization as a new approach in nanomedicine

(2019) Anna Laura Capriotti et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Light/pH-Triggered Biomimetic Red Blood Cell Membranes Camouflaged Small Molecular Drug Assemblies for Imaging-Guided Combinational Chemo-Photothermal Therapy

(2019) Shefang Ye et al.   ACS Applied Materials & Interfaces

Oral delivery of nanoparticles - let’s not forget about the protein corona

(2019) Alberto Berardi et al.   Expert Opinion on Drug Delivery

Serum type and concentration both affect the protein-corona composition of PLGA nanoparticles

(2019) Katrin Partikel et al.   Beilstein Journal of Nanotechnology

Functionalization of Liposomes with Hydrophilic Polymers Results in Macrophage Uptake Independent of the Protein Corona

(2019) Claudia Weber et al.   BIOMACROMOLECULES

Cross-Linked Poly(ethylene glycol) Shells for Nanoparticles: Enhanced Stealth Effect and Colloidal Stability

(2019) Dianqi Li et al.   LANGMUIR

Shielding and stealth effects of zwitterion moieties in double-functionalized silica nanoparticles

(2019) Lívia M.D. Loiola et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

pH‐Responsive PEG‐Shedding and Targeting Peptide‐Modified Nanoparticles for Dual‐Delivery of Irinotecan and microRNA to Enhance Tumor‐Specific Therapy

(2019) Vivian Juang et al.   Small

Brain-targeted drug delivery by manipulating protein corona functions

(2019) Zui Zhang et al.   Nature Communications

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

(2018) Alysia Cox et al.   ACS Nano

Preservation of the soft protein corona in distinct flow allows identification of weakly bound proteins

(2018) C. Weber et al.   Acta Biomaterialia

Beyond the protein corona – lipids matter for biological response of nanocarriers

(2018) Julius Müller et al.   Acta Biomaterialia

How Low Can You Go? Low Densities of Poly(ethylene glycol) Surfactants Attract Stealth Proteins

(2018) Senne Seneca et al.   MACROMOLECULAR BIOSCIENCE

Qualitative and semiquantitative analysis of the protein coronas associated to different functionalized nanoparticles

(2018) Francesca Pederzoli et al.   Nanomedicine

In vivo formation of protein corona on gold nanoparticles. The effect of their size and shape

(2018) Rafaela García-Álvarez et al.   Nanoscale

Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery

(2018) Jonathan O. Martinez et al.   Theranostics

The in vivo fates of plant viral nanoparticles camouflaged using self-proteins: overcoming immune recognition

(2018) N. M. Gulati et al.   Journal of Materials Chemistry B

Dense and Dynamic Polyethylene Glycol Shells Cloak Nanoparticles from Uptake by Liver Endothelial Cells for Long Blood Circulation

(2018) Hao Zhou et al.   ACS Nano

Anti-polyethylene glycol antibodies alter the protein corona deposited on nanoparticles and the physiological pathways regulating their fate in vivo

(2018) Philippe Grenier et al.   JOURNAL OF CONTROLLED RELEASE

Nanoengineering of Poly(ethylene glycol) Particles for Stealth and Targeting

(2018) Jiwei Cui et al.   LANGMUIR

Effects of Protein Corona on Active and Passive Targeting of Cyclic RGD Peptides Functionalized PEGylation Nanoparticles

(2018) Gaoxing Su et al.   MOLECULAR PHARMACEUTICS

Design and biological activity of novel stealth polymeric lipid nanoparticles for enhanced delivery of hydrophobic photodynamic therapy drugs

(2018) Mathias Viard et al.   Nanomedicine-Nanotechnology Biology and Medicine

In situ low-immunogenic albumin-conjugating-corona guiding nanoparticles for tumor-targeting chemotherapy

(2018) Zhenbao Li et al.   Biomaterials Science

Trends towards Biomimicry in Theranostics

(2018) Michael Evangelopoulos et al.   Nanomaterials

Dual Functionalization of Nanoparticles for Generating Corona-Free and Noncytotoxic Silica Nanoparticles

(2018) Jessica Fernanda Affonso de Oliveira et al.   ACS Applied Materials & Interfaces

The Human In Vivo Biomolecule Corona onto PEGylated Liposomes: A Proof-of-Concept Clinical Study

(2018) Marilena Hadjidemetriou et al.   ADVANCED MATERIALS

Protein Corona Formed from Different Blood Plasma Proteins Affects the Colloidal Stability of Nanoparticles Differently

(2018) Yan Teck Ho et al.   BIOCONJUGATE CHEMISTRY

Cloaking nanoparticles with protein corona shield for targeted drug delivery

(2018) Jun Yong Oh et al.   Nature Communications

Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improve long circulation and enhance cellular uptake in cancer therapy

(2018) Lu Zhong et al.   Acta Pharmaceutica Sinica B

Tuning complement activation and pathway through controlled molecular architecture of dextran chains in nanoparticle corona

(2017) Jean-Baptiste Coty et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The Protein Corona of PEGylated PGMA-Based Nanoparticles is Preferentially Enriched with Specific Serum Proteins of Varied Biological Function

(2017) Priya S. R. Naidu et al.   LANGMUIR

Concentration-dependent protein adsorption at the nano–bio interfaces of polymeric nanoparticles and serum proteins

(2017) Tian-Xu Zhang et al.   Nanomedicine

Engineered biomimetic nanovesicles show intrinsic anti-inflammatory properties for the treatment of inflammatory bowel diseases

(2017) Claudia Corbo et al.   Nanoscale

A comparison of the human and mouse protein corona profiles of functionalized SiO2 nanocarriers

(2017) A. Solorio-Rodríguez et al.   Nanoscale

A protein corona-enabled blood test for early cancer detection

(2017) D. Caputo et al.   Nanoscale

Protein Corona: Impact of Lymph Versus Blood in a Complex In Vitro Environment

(2017) Debora Bonvin et al.   Small

Personalized protein corona on nanoparticles and its clinical implications

(2017) Claudia Corbo et al.   Biomaterials Science

Protein corona in drug delivery for multimodal cancer therapy in vivo

(2017) Eugenia Li Ling Yeo et al.   Nanoscale

Probing fibronectin conformation on a protein corona layer around nanoparticles

(2017) Mohammad Raoufi et al.   Nanoscale

Hyaluronic Acid Coated Chitosan Nanoparticles Reduced the Immunogenicity of the Formed Protein Corona

(2017) Abdulaziz Almalik et al.   Scientific Reports

Zwitterionic-Modified Starch-Based Stealth Micelles for Prolonging Circulation Time and Reducing Macrophage Response

(2016) Lei Ye et al.   ACS Applied Materials & Interfaces

Regulation of Macrophage Recognition through the Interplay of Nanoparticle Surface Functionality and Protein Corona

(2016) Krishnendu Saha et al.   ACS Nano

Lipid-Mediated Targeting with Membrane-Wrapped Nanoparticles in the Presence of Corona Formation

(2016) Fangda Xu et al.   ACS Nano

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

‘Stealth’ nanoparticles evade neural immune cells but also evade major brain cell populations: Implications for PEG-based neurotherapeutics

(2016) Stuart I. Jenkins et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination

(2016) Yi-Nan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

(2016) Claudia Corbo et al.   Nanomedicine

Time-evolution of in vivo protein corona onto blood-circulating PEGylated liposomal doxorubicin (DOXIL) nanoparticles

(2016) Marilena Hadjidemetriou et al.   Nanoscale

Synthetic nanoparticles camouflaged with biomimetic erythrocyte membranes for reduced reticuloendothelial system uptake

(2016) Lang Rao et al.   NANOTECHNOLOGY

Biomimetic proteolipid vesicles for targeting inflamed tissues

(2016) R. Molinaro et al.   NATURE MATERIALS

Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers

(2016) Susanne Schöttler et al.   Nature Nanotechnology

The concept of bio-corona in modulating the toxicity of engineered nanomaterials (ENM)

(2016) Dana Westmeier et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Gold Nanoparticle-Enabled Blood Test for Early Stage Cancer Detection and Risk Assessment

(2015) Tianyu Zheng et al.   ACS Applied Materials & Interfaces

Monoclonal Antibody-Functionalized Multilayered Particles: Targeting Cancer Cells in the Presence of Protein Coronas

(2015) Qiong Dai et al.   ACS Nano

In Vivo Biomolecule Corona around Blood-Circulating, Clinically Used and Antibody-Targeted Lipid Bilayer Nanoscale Vesicles

(2015) Marilena Hadjidemetriou et al.   ACS Nano

Protein corona hampers targeting potential of MUC1 aptamer functionalized SN-38 core–shell nanoparticles

(2015) Behrang Shiri Varnamkhasti et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Polyethylene glycol (PEG)-dendron phospholipids as innovative constructs for the preparation of super stealth liposomes for anticancer therapy

(2015) Gianfranco Pasut et al.   JOURNAL OF CONTROLLED RELEASE

Stealth Effect of Biomolecular Corona on Nanoparticle Uptake by Immune Cells

(2015) Giulio Caracciolo et al.   LANGMUIR

Enabling cytoplasmic delivery and organelle targeting by surface modification of nanocarriers

(2015) Alessandro Parodi et al.   Nanomedicine

Erythrocyte membrane-coated NIR-triggered biomimetic nanovectors with programmed delivery for photodynamic therapy of cancer

(2015) Hui Ding et al.   Nanoscale

The biomolecular corona of nanoparticles in circulating biological media

(2015) D. Pozzi et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Analytical Methods for Characterizing the Nanoparticle–Protein Corona

(2014) Anna Laura Capriotti et al.   CHROMATOGRAPHIA

Albumin and its application in drug delivery

(2014) Darrell Sleep   Expert Opinion on Drug Delivery

Effects of poly(ethylene glycol) grafting density on the tumor targeting efficacy of nanoparticles with ligand modification

(2013) Shidong Zhang et al.   DRUG DELIVERY

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Applications of Surface Plasmon Resonance (SPR) for the Characterization of Nanoparticles Developed for Biomedical Purposes

(2012) Mara Canovi et al.   SENSORS

Zwitteration As an Alternative to PEGylation

(2011) Zaki G. Estephan et al.   LANGMUIR