期刊
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fcell.2020.00204
关键词
asthma; chronic rhinosinusitis; epithelium; allergic rhinitis (AR); inflammation
资金
- Aatos Erkko Foundation
- Finnish Medical Society Duodecim
- Finnish ORL-HNS Foundation
- Finnish Society of Allergology and Immunology
- State funding for university-level health research [TYH2018103, TYH2019322]
- Tampere Tuberculosis association
- Vaino and Laina Kivi Foundation
- Yrjo Jahnsson Foundation
Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the airways. This review links environmental factors to host epithelial immunity in airway diseases. Understanding altered homeostasis of the airway epithelium might provide important targets for diagnostics and therapy of chronic airway diseases.
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