Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer
出版年份 2020 全文链接
标题
Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer
作者
关键词
-
出版物
Frontiers in Oncology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-04-16
DOI
10.3389/fonc.2020.00474
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Roles of Mitochondrial SIRT4 in Cellular Metabolism
- (2019) Zheying Min et al. Frontiers in Endocrinology
- SIRT4 inhibits the proliferation, migration, and invasion abilities of thyroid cancer cells by inhibiting glutamine metabolism
- (2019) Zhouxun Chen et al. OncoTargets and Therapy
- Mitochondrial function, metabolic regulation and human disease viewed through the prism of sirtuin 4 (SIRT4) functions
- (2019) Cora N. Betsinger et al. JOURNAL OF PROTEOME RESEARCH
- SIRT4 and Its Roles in Energy and Redox Metabolism in Health, Disease and During Exercise
- (2019) Yumei Han et al. Frontiers in Physiology
- Extranuclear Sirtuins and Metabolic Stress
- (2018) Mahmoud-Sobhy Elkhwanky et al. ANTIOXIDANTS & REDOX SIGNALING
- Sirtuin-4 (SIRT4), a therapeutic target with oncogenic and tumor-suppressive activity in cancer
- (2018) Guoyu Huang et al. OncoTargets and Therapy
- Knockout of SIRT4 decreases chemosensitivity to 5‑FU in colorectal cancer cells
- (2018) Yuanyuan Zhu et al. Oncology Letters
- Crystal structures of the mitochondrial deacylase Sirtuin 4 reveal isoform-specific acyl recognition and regulation features
- (2017) Martin Pannek et al. Nature Communications
- SIRT4 regulates cancer cell survival and growth after stress
- (2016) Seung Min Jeong et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mitochondrial Sirtuins in Cancer: Emerging Roles and Therapeutic Potential
- (2016) J. George et al. CANCER RESEARCH
- Using mitochondrial sirtuins as drug targets: disease implications and available compounds
- (2016) Melanie Gertz et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Sirt4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity
- (2016) Yu-Xuan Luo et al. EUROPEAN HEART JOURNAL
- Mitochondrial sirtuins in the heart
- (2016) Heiko Bugger et al. HEART FAILURE REVIEWS
- Molecular modeling, dynamics studies and density functional theory approaches to identify potential inhibitors of SIRT4 protein from Homo sapiens : a novel target for the treatment of type 2 diabetes
- (2016) Sanjay K. Choubey et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Acetylation of Mitochondrial Trifunctional Protein α-Subunit Enhances Its Stability To Promote Fatty Acid Oxidation and Is Decreased in Nonalcoholic Fatty Liver Disease
- (2016) Liang Guo et al. MOLECULAR AND CELLULAR BIOLOGY
- SIRT4 inhibits malignancy progression of NSCLCs, through mitochondrial dynamics mediated by the ERK-Drp1 pathway
- (2016) L Fu et al. ONCOGENE
- Downregulation of SIRT4 Expression Is Associated with Poor Prognosis in Esophageal Squamous Cell Carcinoma
- (2016) Yujiro Nakahara et al. ONCOLOGY
- SIRT4 overexpression protects against diabetic nephropathy by inhibiting podocyte apoptosis
- (2016) Jian-Xia Shi et al. Experimental and Therapeutic Medicine
- Decreased sirtuin 4 expression is associated with poor prognosis in patients with invasive breast cancer
- (2016) Qingyu Shi et al. Oncology Letters
- SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK
- (2016) Linh Ho et al. Aging-US
- Sirtuin-4 (SIRT4) is downregulated and associated with some clinicopathological features in gastric adenocarcinoma
- (2015) Guoyu Huang et al. BIOMEDICINE & PHARMACOTHERAPY
- Tumour-suppressive function of SIRT4 in human colorectal cancer
- (2015) M Miyo et al. BRITISH JOURNAL OF CANCER
- Sirtuins in Cancer: a Balancing Act between Genome Stability and Metabolism
- (2015) Seung Min Jeong et al. MOLECULES AND CELLS
- CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4
- (2015) L Wang et al. Cell Death & Disease
- Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium
- (2015) Carla Bartosch et al. Oncotarget
- Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity
- (2014) Rommel A. Mathias et al. CELL
- SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism
- (2013) Seung Min Jeong et al. CANCER CELL
- The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4
- (2013) Alfred Csibi et al. CELL
- Therapeutic strategies impacting cancer cell glutamine metabolism
- (2013) Michael J Lukey et al. Future Medicinal Chemistry
- SIRT4 Protein Suppresses Tumor Formation in Genetic Models of Myc-induced B Cell Lymphoma
- (2013) Seung Min Jeong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT4 Represses Peroxisome Proliferator-Activated Receptor α Activity To Suppress Hepatic Fat Oxidation
- (2013) Gaëlle Laurent et al. MOLECULAR AND CELLULAR BIOLOGY
- SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase
- (2013) Gaëlle Laurent et al. MOLECULAR CELL
- Sorting out functions of sirtuins in cancer
- (2013) M Roth et al. ONCOGENE
- An acetylome peptide microarray reveals specificities and deacetylation substrates for all human sirtuin isoforms
- (2013) David Rauh et al. Nature Communications
- Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells
- (2011) S. L. Colombo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
- (2009) Ping Gao et al. NATURE
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice
- (2008) Qiong Wang et al. HEPATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started