Hypoxia Inducible Factors’ Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches
出版年份 2020 全文链接
标题
Hypoxia Inducible Factors’ Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches
作者
关键词
-
出版物
Cancers
Volume 12, Issue 4, Pages 979
出版商
MDPI AG
发表日期
2020-04-16
DOI
10.3390/cancers12040979
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Open Data for Differential Network Analysis in Glioma
- (2020) Claire Jean-Quartier et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Whole slide images reflect DNA methylation patterns of human tumors
- (2020) Hong Zheng et al. npj Genomic Medicine
- Activation of dopamine receptor 2 (DRD2) prompts transcriptomic and metabolic plasticity in glioblastoma
- (2019) Seamus P. Caragher et al. JOURNAL OF NEUROSCIENCE
- Quantifying radiation therapy response using apparent diffusion coefficient (ADC) parametric mapping of pediatric diffuse intrinsic pontine glioma: a report from the pediatric brain tumor consortium
- (2019) Rafael Ceschin et al. JOURNAL OF NEURO-ONCOLOGY
- Intratumoral genetic and functional heterogeneity in pediatric glioblastoma
- (2019) Mary Hoffman et al. CANCER RESEARCH
- H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo
- (2019) André B. Silveira et al. ACTA NEUROPATHOLOGICA
- cIMPACT‐NOW: a practical summary of diagnostic points from Round 1 updates
- (2019) David N. Louis et al. BRAIN PATHOLOGY
- Chronic mild hypoxia promotes hippocampal neurogenesis involving Notch1 signaling in epileptic rats
- (2019) Can Sun et al. BRAIN RESEARCH
- MYC Regulates the HIF2α Stemness Pathway via Nanog and Sox2 to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells
- (2019) Bikul Das et al. CANCER RESEARCH
- Signal Transduction in Diffuse Intrinsic Pontine Glioma
- (2019) Ryan J. Duchatel et al. PROTEOMICS
- Electrical and synaptic integration of glioma into neural circuits
- (2019) Humsa S. Venkatesh et al. NATURE
- Targeting reduced mitochondrial DNA quantity as a therapeutic approach in pediatric high-grade gliomas
- (2019) Han Shen et al. NEURO-ONCOLOGY
- Acute vs. Chronic vs. Cyclic Hypoxia: Their Differential Dynamics, Molecular Mechanisms, and Effects on Tumor Progression
- (2019) Saxena et al. Biomolecules
- Diagnostics and treatment of diffuse intrinsic pontine glioma: where do we stand?
- (2019) Fatma E. El-Khouly et al. JOURNAL OF NEURO-ONCOLOGY
- 3D extracellular matrix microenvironment in bioengineered tissue models of primary pediatric and adult brain tumors
- (2019) Disha Sood et al. Nature Communications
- Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity
- (2019) Blandin et al. Cancers
- Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
- (2018) Debangshu Samanta et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial
- (2018) Alan Mackay et al. CANCER CELL
- Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma
- (2018) Jacques Grill et al. JOURNAL OF CLINICAL ONCOLOGY
- Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries
- (2018) Lindsey M. Hoffman et al. JOURNAL OF CLINICAL ONCOLOGY
- Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
- (2018) Mariella G. Filbin et al. SCIENCE
- Beyond the Blood:Brain Barrier: The Importance of Central Nervous System (CNS) Pharmacokinetics for the Treatment of CNS Tumors, Including Diffuse Intrinsic Pontine Glioma
- (2018) Katherine Elizabeth Warren Frontiers in Oncology
- Characterization of the ventricular-subventricular stem cell niche during human brain development
- (2018) Amanda M. Coletti et al. DEVELOPMENT
- Glioblastoma Chemoresistance: The Double Play by Microenvironment and Blood-Brain Barrier
- (2018) Martina Da Ros et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Human glioblastoma arises from subventricular zone cells with low-level driver mutations
- (2018) Joo Ho Lee et al. NATURE
- International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma
- (2018) Maria Tsoli et al. JOURNAL OF NEURO-ONCOLOGY
- Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location
- (2018) David Castel et al. Acta Neuropathologica Communications
- New horizons in hypoxia signaling pathways
- (2017) Christopher W. Pugh et al. EXPERIMENTAL CELL RESEARCH
- Trans sodium crocetinate with temozolomide and radiation therapy for glioblastoma multiforme
- (2017) John L. Gainer et al. JOURNAL OF NEUROSURGERY
- Correlation of 18 F-FDG PET and MRI Apparent Diffusion Coefficient Histogram Metrics with Survival in Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium
- (2017) Katherine A. Zukotynski et al. JOURNAL OF NUCLEAR MEDICINE
- Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency
- (2017) D. Sainz de la Maza et al. Oxidative Medicine and Cellular Longevity
- REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature
- (2017) Shavali Shaik et al. Oncotarget
- Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1α axis inhibition
- (2017) Aurélia Nguyen et al. Oncotarget
- Prognostic impact of the 2016 WHO classification of diffuse gliomas in the French POLA cohort
- (2016) Emeline Tabouret et al. ACTA NEUROPATHOLOGICA
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Dynamic regulation of stem cell specification and maintenance by hypoxia-inducible factors
- (2016) Gregg L. Semenza MOLECULAR ASPECTS OF MEDICINE
- Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
- (2016) Caroline Wigerup et al. PHARMACOLOGY & THERAPEUTICS
- Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes
- (2015) David Castel et al. ACTA NEUROPATHOLOGICA
- Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma
- (2014) Kathryn R Taylor et al. NATURE GENETICS
- Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007–2011
- (2014) Quinn T. Ostrom et al. NEURO-ONCOLOGY
- Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma
- (2014) Nada M. S. Al-Saffar et al. PLoS One
- A Prominin-1-Rich Pediatric Glioblastoma: Biologic Behavior Is Determined by Oxygen Tension-Modulated CD133 Expression but Not Accompanied by Underlying Molecular Profiles
- (2014) Laura K. Donovan et al. Translational Oncology
- Preoperative dynamic contrast-enhanced MRI correlates with molecular markers of hypoxia and vascularity in specific areas of intratumoral microenvironment and is predictive of patient outcome
- (2013) Randy L. Jensen et al. NEURO-ONCOLOGY
- H3F3A K27M mutations in thalamic gliomas from young adult patients
- (2013) Koki Aihara et al. NEURO-ONCOLOGY
- K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
- (2012) Dong-Anh Khuong-Quang et al. ACTA NEUROPATHOLOGICA
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- Treatment of high-grade glioma in children and adolescents
- (2011) T. J. MacDonald et al. NEURO-ONCOLOGY
- Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
- (2010) Ahmed Mohyeldin et al. Cell Stem Cell
- A Distinct Spectrum of Copy Number Aberrations in Pediatric High-Grade Gliomas
- (2010) D. A. Bax et al. CLINICAL CANCER RESEARCH
- HIF-1 and HIF-2 transcription factors — Similar but not identical
- (2010) Agnieszka Loboda et al. MOLECULES AND CELLS
- Magnetic Resonance Imaging Characteristics of Glioblastoma Multiforme: Implications for Understanding Glioma Ontogeny
- (2010) Leif-Erik Bohman et al. NEUROSURGERY
- Intratumoral Hypoxic Gradient Drives Stem Cells Distribution and MGMT Expression in Glioblastoma
- (2010) Francesca Pistollato et al. STEM CELLS
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling
- (2009) C. Yang et al. CANCER RESEARCH
- Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α
- (2009) A Soeda et al. ONCOGENE
- Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma
- (2008) Francesca Pistollato et al. STEM CELLS
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