Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination

Vaccine priming is restricted to draining lymph nodes and controlled by adjuvant-mediated antigen uptake

(2017) Frank Liang et al.   Science Translational Medicine

Biomimetically Engineered Demi-Bacteria Potentiate Vaccination against Cancer

(2017) Dezhi Ni et al.   Advanced Science

One-Shot Immunomodulatory Nanodiamond Agents for Cancer Immunotherapy

(2016) Yu Zhang et al.   ADVANCED MATERIALS

A Powerful CD8+T-Cell Stimulating D-Tetra-Peptide Hydrogel as a Very Promising Vaccine Adjuvant

(2016) Zichao Luo et al.   ADVANCED MATERIALS

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

(2016) Avery D. Posey et al.   IMMUNITY

Neoantigen landscape dynamics during human melanoma–T cell interactions

(2016) Els M. E. Verdegaal et al.   NATURE

Sustainable polymers from renewable resources

(2016) Yunqing Zhu et al.   NATURE

MUC1 and survivin combination tumor gene vaccine generates specific immune responses and anti-tumor effects in a murine melanoma model

(2016) Haihong Zhang et al.   VACCINE

Saponin-based adjuvants induce cross-presentation in dendritic cells by intracellular lipid body formation

(2016) Martijn H. den Brok et al.   Nature Communications

Exploration of graphene oxide as an intelligent platform for cancer vaccines

(2015) Hua Yue et al.   Nanoscale

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

Polymeric micro/nanoparticles: Particle design and potential vaccine delivery applications

(2015) Hua Yue et al.   VACCINE

Injectable cryogel-based whole-cell cancer vaccines

(2015) Sidi A. Bencherif et al.   Nature Communications

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

(2014) Jaeyun Kim et al.   NATURE BIOTECHNOLOGY

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

Nanoparticles-based multi-adjuvant whole cell tumor vaccine for cancer immunotherapy

(2013) Shi-Ying Liu et al.   BIOMATERIALS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Nanoparticle vaccines

(2013) Liang Zhao et al.   VACCINE

Self-Healing Microencapsulation of Biomacromolecules without Organic Solvents

(2012) Samuel E. Reinhold et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Active self-healing encapsulation of vaccine antigens in PLGA microspheres

(2012) Kashappa-Goud H. Desai et al.   JOURNAL OF CONTROLLED RELEASE

Microcosmic Mechanisms for Protein Incomplete Release and Stability of Various Amphiphilic mPEG-PLA Microspheres

(2012) Yi Wei et al.   LANGMUIR

Biodegradable Microcapsules Prepared by Self-Healing of Porous Microspheres

(2012) Xiang-Ming Na et al.   ACS Macro Letters

Acid-Sensing Ion Channels Contribute to the Effect of Acidosis on the Function of Dendritic Cells

(2011) J. Tong et al.   JOURNAL OF IMMUNOLOGY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

(2011) James J. Moon et al.   NATURE MATERIALS

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

(2010) Tomonori Nochi et al.   NATURE MATERIALS

Metabolic acidosis: pathophysiology, diagnosis and management

(2010) Jeffrey A. Kraut et al.   Nature Reviews Nephrology

Chitosan-based delivery systems for protein therapeutics and antigens

(2009) Maryam Amidi et al.   ADVANCED DRUG DELIVERY REVIEWS

Infection-mimicking materials to program dendritic cells in situ

(2009) Omar A. Ali et al.   NATURE MATERIALS

The molecular basis of the host response to lipopolysaccharide

(2009) Clare E. Bryant et al.   NATURE REVIEWS MICROBIOLOGY

In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice

(2009) O. A. Ali et al.   Science Translational Medicine

Influence of Different Polyelectrolytes on Layer-by-Layer Microcapsule Properties: Encapsulation Efficiency and Colloidal and Temperature Stability

(2008) Wing Cheung Mak et al.   CHEMISTRY OF MATERIALS

Monocyte chemoattractant protein-1: A key mediator in inflammatory processes

(2008) Esther Melgarejo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

An Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models

(2008) L. G. Burdelya et al.   SCIENCE

Immunological decision-making: how does the immune system decide to mount a helper T-cell response?

(2007) Gerard E. Kaiko et al.   IMMUNOLOGY