Broad-spectrum anti-CRISPR proteins facilitate horizontal gene transfer

Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing

(2019) Benjamin P. Kleinstiver et al.   NATURE BIOTECHNOLOGY

CRISPResso2 provides accurate and rapid genome editing sequence analysis

(2019) Kendell Clement et al.   NATURE BIOTECHNOLOGY

Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins

(2019) Yalan Zhu et al.   MOLECULAR CELL

Discovery and Characterization of Cas9 Inhibitors Disseminated across Seven Bacterial Phyla

(2019) Ruben V. Uribe et al.   Cell Host & Microbe

Broad-spectrum enzymatic inhibition of CRISPR-Cas12a

(2019) Gavin J. Knott et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An anti-CRISPR protein disables type V Cas12a by acetylation

(2019) Liyong Dong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2

(2019) Annoj Thavalingam et al.   Nature Communications

Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome

(2019) Kevin J Forsberg et al.   eLife

Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing

(2019) Bianca Garcia et al.   Cell Reports

Versatile High-Throughput Fluorescence Assay for Monitoring Cas9 Activity

(2018) Kyle J. Seamon et al.   ANALYTICAL CHEMISTRY

Bacteriophage Cooperation Suppresses CRISPR-Cas3 and Cas9 Immunity

(2018) Adair L. Borges et al.   CELL

An Attenuated CRISPR-Cas System in Enterococcus faecalis Permits DNA Acquisition

(2018) Karthik Hullahalli et al.   mBio

Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins

(2018) Alexander P. Hynes et al.   Nature Communications

Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race

(2018) Liang Liu et al.   MOLECULAR CELL

Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

(2018) Fuguo Jiang et al.   MOLECULAR CELL

Structural basis of CRISPR–SpyCas9 inhibition by an anti-CRISPR protein

(2017) De Dong et al.   NATURE

Exploiting CRISPR-Cas to manipulate Enterococcus faecalis populations

(2017) Karthik Hullahalli et al.   eLife

An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9

(2017) Alexander P. Hynes et al.   Nature Microbiology

Disabling Cas9 by an anti-CRISPR DNA mimic

(2017) Jiyung Shin et al.   Science Advances

Chlorhexidine Induces VanA-Type Vancomycin Resistance Genes in Enterococci

(2016) Pooja Bhardwaj et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Naturally Occurring Off-Switches for CRISPR-Cas9

(2016) April Pawluk et al.   CELL

Viruses and mobile elements as drivers of evolutionary transitions

(2016) Eugene V. Koonin   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

CRISPR-Cas and Restriction-Modification Act Additively against Conjugative Antibiotic Resistance Plasmid Transfer in Enterococcus faecalis

(2016) Valerie J. Price et al.   mSphere

Multiple mechanisms for CRISPR–Cas inhibition by anti-CRISPR proteins

(2015) Joseph Bondy-Denomy et al.   NATURE

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Processing-Independent CRISPR RNAs Limit Natural Transformation in Neisseria meningitidis

(2013) Yan Zhang et al.   MOLECULAR CELL

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system

(2012) Joe Bondy-Denomy et al.   NATURE

Horizontal gene transfer and the genomics of enterococcal antibiotic resistance

(2010) Kelli L Palmer et al.   CURRENT OPINION IN MICROBIOLOGY

The Escherichia coli CRISPR System Protects from   Lysogenization, Lysogens, and Prophage Induction

(2010) R. Edgar et al.   JOURNAL OF BACTERIOLOGY

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

Bacteriophage resistance mechanisms

(2010) Simon J. Labrie et al.   NATURE REVIEWS MICROBIOLOGY

Multidrug-Resistant Enterococci Lack CRISPR-cas

(2010) K. L. Palmer et al.   mBio