Review
Virology
Jingjing He, Yifei Guo, Richeng Mao, Jiming Zhang
Summary: Approximately 15.6% of confirmed COVID-19 patients are asymptomatic. Nearly half of the patients with no symptoms at detection time will develop symptoms later. Children are likely to have a higher proportion of asymptomatic infection than adults. Asymptomatic COVID-19 patients could have abnormal laboratory and radiational manifestations, which can be used as screening strategies to identify asymptomatic infection.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Virology
Lutfiye Karcioglu Batur, Nezih Hekim
Summary: This study identified a significant correlation between polymorphisms in the IL-10 gene at rs1800896, IL-17A gene at rs2275913, and IL-17F gene at rs763780, and the prevalence and mortality rates of COVID-19 among populations of 23 countries.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Review
Virology
Charles W. Stratton, Yi-Wei Tang, Hongzhou Lu
Summary: COVID-19 is considered a global public health emergency and therapy should be based on the pathogenic mechanisms, including testing and treatment, correcting hypoxia, reducing viral load, addressing hyperinflammation, and hypercoagulability, among six major therapeutic goals identified.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Surgery
Iris Naudin, Anne Long, Christophe Michel, Bertrand Devigne, Antoine Millon, Nellie Della-Schiava
Summary: The COVID-19 pandemic is having a widespread impact, with severe cases potentially leading to complications such as venous and arterial thrombosis, even requiring amputation in some instances.
JOURNAL OF VASCULAR SURGERY
(2021)
Review
Medicine, General & Internal
Chenze Li, Dao Wen Wang, Chunxia Zhao
Summary: The 2019 novel coronavirus disease (COVID-19) is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by severe respiratory symptoms and widespread organ injuries. Cardiovascular impairment is a notable extrapulmonary manifestation, with reports reviewed and clinical characteristics summarized for frontline physicians, along with discussions on possible mechanisms and medication applications.
JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE
(2021)
Article
Medicine, General & Internal
Luke Carson, Christopher Kui, Gemma Smith, Anand K. Dixit
Summary: During the COVID-19 pandemic, there was a significant reduction in stroke admissions and transient ischemic attack referrals. Questionnaire findings revealed that some patients experienced reduced physical activity, increased isolation, and delayed seeking medical help due to the pandemic.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Kavita Narang, Linda M. Szymanski, Sunanda Kane, Carl H. Rose
Summary: Pregnant women with COVID-19 are at risk for various complications beyond respiratory issues. This case study reported a pregnant patient with acute pancreatitis associated with COVID-19 pneumonia, resulting in preterm labor and subsequent delivery of a healthy baby with negative SARS-CoV-2 screening. Acute pancreatitis is a rare complication of primary COVID-19 infection.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Pathology
Elisabet Pujadas, Michael Beaumont, Hardik Shah, Nadine Schrode, Nancy Francoeur, Sanjana Shroff, Clare Bryce, Zachary Grimes, Jill Gregory, Ryan Donnelly, Mary E. Fowkes, Kristin G. Beaumont, Robert Sebra, Carlos Cordon-Cardo
Summary: The study utilized advanced molecular techniques to identify different regulatory pathways and effectors in COVID-19 rapid autopsy tissues, revealing diverse expression patterns of virus receptors. Digital spatial profiling could distinguish different disease phenotypes. These findings contribute to a better understanding of the pathophysiology of COVID-19.
AMERICAN JOURNAL OF PATHOLOGY
(2021)
Article
Multidisciplinary Sciences
Yuta Kawakami, Shuko Nojiri, Daisuke Nakamoto, Yoshiki Irie, Satoshi Miyazawa, Manabu Kuroki, Yuji Nishizaki
Summary: The Japanese government implemented policies to control human mobility in 2020 as a measure to prevent the spread of COVID-19. This study investigated the relationship between human mobility and COVID-19 cases at the prefectural level in Japan. Mobile phone data was used to calculate travel mobility within prefectures from March to December 2020. The study found that the COVID-19 infection acceleration indicator (IAI) could be used to predict COVID-19 cases, and controlling human mobility was important in controlling infectious diseases during a pandemic.
SCIENTIFIC REPORTS
(2023)
Article
Infectious Diseases
Muge Cevik, Syed Arefinul Haque, Jennifer Manne-Goehler, Krutika Kuppalli, Paul E. Sax, Maimuna S. Majumder, Chloe Orkin
Summary: The study showed that less than one-third of principal investigators in COVID-19 clinical trials are women, which is significantly lower compared to breast cancer and type 2 diabetes mellitus trials. This gender disparity may indicate a lack of female leadership in international clinical trials and research activities during health emergencies.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Infectious Diseases
Maya Nitecki, Boris Taran, Itay Ketko, Gil Geva, Roey Yosef, Itay Toledo, Gilad Twig, Eva Avramovitch, Barak Gordon, Estela Derazne, Noam Fink, Ariel Furer
Summary: This study assessed the utility of self-reported symptoms in identifying positive COVID-19 cases among predominantly healthy young adults in a military setting. The results showed that loss of taste or smell, suspected exposure, and fever were consistently associated with positive test results in this population.
CLINICAL MICROBIOLOGY AND INFECTION
(2021)
Article
Medicine, General & Internal
Wongi Woo, Vincent Kipkorir, Adina Maria Marza, Shadi Hamouri, Omar Albawaih, Arkadeep Dhali, Wooshik Kim, Zarir F. Udwadia, Abdulqadir J. Nashwan, Nissar Shaikh, Alessandro Belletti, Giovanni Landoni, Diego Palumbo, Sarya Swed, Bisher Sawaf, Danilo Buonsenso, Ines Pimenta, Filipe Andre Gonzalez, Giuseppe Fiorentino, Muhammad Redzwan S. Rashid Ali, Alvaro Quincho-Lopez, Mohammad Javanbakht, Ayat Alhakeem, Muhammad Mohsin Khan, Sangam Shah, Moezedin Javad Rafiee, Sri Rama Ananta Nagabhushanam Padala, Sebastian Diebel, Seung Hwan Song, Du-young Kang, Duk Hwan Moon, Hye Sun Lee, Juyeon Yang, Luke Flower, Dong Keon Yon, Seung Won Lee, Jae Il Shin, Sungsoo Lee
Summary: Pneumothorax and pneumomediastinum in non-intubated COVID-19 patients are associated with high mortality, with comorbidities, bilateral pneumothorax, and fever at presentation being predictors for mortality. The CoBiF score can predict mortality and simplify the management of high-risk patients in clinical settings.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Miri Hyun, Ji Yeon Lee, Jae Seok Park, Jin Young Kim, Hyun Ah Kim
Summary: This study evaluated the clinical characteristics of asymptomatic patients with COVID-19 and found that most patients were discharged without significant events during hospitalization. However, it was difficult to predict subsequent events based on initial chest radiographs or oxygen saturation at admission.
JOURNAL OF EPIDEMIOLOGY AND GLOBAL HEALTH
(2021)
Article
Multidisciplinary Sciences
Zuiyuan Guo, Dan Xiao
Summary: The study utilized a computer model to simulate the occurrence, infection, detection, and quarantine of asymptomatic SARS-CoV-2 cases in the community. Implementation of control measures such as active tracing, testing, treatment, and quarantine resulted in a significant reduction in the number of cases and prevented disease outbreaks caused by asymptomatic individuals.
SCIENTIFIC REPORTS
(2021)
Article
Public, Environmental & Occupational Health
Yu Liu, Dan Wang, Hao Xu, Ying Xiao, Cui Chen, Ru-Nan Chen, Liang-Hao Hu, Zhao-Shen Li
Summary: The study showed that the Chinese public has a good overall knowledge of COVID-19, but there are still uncertainties in some aspects. Most participants believed in person-to-person transmission, while some believed in animal-to-person transmission. The effectiveness of overall control measures was acknowledged by the majority of participants, with the agreement correlated with the number of regional existing confirmed cases.