Inflammasome Adaptor ASC Is Highly Elevated in Lung Over Plasma and Relates to Inflammation and Lung Diffusion in the Absence of Speck Formation

Electronic vs Combustible Cigarette Effects on Inflammasome Component Release into Human Lung

(2019) MuChun Tsai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

(2018) Dave Boucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Single-Molecule Fluorescence Reveals the Oligomerization and Folding Steps Driving the Prion-like Behavior of ASC

(2018) Yann Gambin et al.   JOURNAL OF MOLECULAR BIOLOGY

Assessment of ASC specks as a putative biomarker of pyroptosis in myelodysplastic syndromes: an observational cohort study

(2018) Ashley A Basiorka et al.   Lancet Haematology

ASC filament formation serves as a signal amplification mechanism for inflammasomes

(2016) Mathias S. Dick et al.   Nature Communications

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

(2015) Pervinder Sagoo et al.   NATURE MEDICINE

Monocyte Caspase-1 Is Released in a Stable, Active High Molecular Weight Complex Distinct from the Unstable Cell Lysate-Activated Caspase-1

(2015) Obada R. Shamaa et al.   PLoS One

Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes

(2014) Alvin Lu et al.   CELL

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

(2014) Bernardo S Franklin et al.   NATURE IMMUNOLOGY

Tyrosine phosphatase inhibition induces an ASC-dependent pyroptosis

(2012) Mohammed G. Ghonime et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of the Pyrin Inflammasome by Intracellular Burkholderia cenocepacia

(2012) M. A. Gavrilin et al.   JOURNAL OF IMMUNOLOGY

Mycoplasma Suppression of THP-1 Cell TLR Responses Is Corrected with Antibiotics

(2010) Ekaterina Zakharova et al.   PLoS One

Pyrin Critical to Macrophage IL-1  Response to Francisella Challenge

(2009) M. A. Gavrilin et al.   JOURNAL OF IMMUNOLOGY