PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4+ and CD8+ T Cells During BVDV Infection in vitro

PD-1/PD-L1 blockade rescue exhausted CD8+ T cells in gastrointestinal stromal tumours via the PI3K/Akt/mTOR signalling pathway

(2019) Rui Zhao et al.   CELL PROLIFERATION

Phosphorylation of PD-1-Y248 is a marker of PD-1-mediated inhibitory function in human T cells

(2019) Kankana Bardhan et al.   Scientific Reports

Detection of persistent pestivirus infection in pudú (Pudu puda) in a captive population of artiodactyls in Chile

(2018) Rodrigo Salgado et al.   BMC Veterinary Research

CTLA‑4 interferes with the HBV‑specific T�cell immune response (Review)

(2018) Hui Cao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Identification of Conserved Amino Acid Substitutions During Serial Infection of Pregnant Cattle and Sheep With Bovine Viral Diarrhea Virus

(2018) Thibaud Kuca et al.   Frontiers in Microbiology

Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections

(2018) Eleni Panagioti et al.   Frontiers in Immunology

PD-1 blockade inhibits lymphocyte apoptosis and restores proliferation and anti-viral immune functions of lymphocyte after CP and NCP BVDV infection in vitro

(2018) Yu Liu et al.   VETERINARY MICROBIOLOGY

Sulfated Hetero-Polysaccharides Protect SH-SY5Y Cells from H2O2-Induced Apoptosis by Affecting the PI3K/Akt Signaling Pathway

(2017) Jing Wang et al.   Marine Drugs

Decreased expression of programmed death 1 on peripheral blood lymphocytes disrupts immune homeostasis in peripartum cardiomyopathy

(2016) Guozhi Xia et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

(2016) Vassiliki A. Boussiotis   NEW ENGLAND JOURNAL OF MEDICINE

Relationship betweenprogrammed cell death-1polymorphisms and clearance of hepatitis B virus

(2015) Y. Ülger et al.   International Journal of Immunogenetics

Immune response to bovine viral diarrhea virus—looking at newly defined targets

(2015) Christopher C. L. Chase et al.   ANIMAL HEALTH RESEARCH REVIEWS

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

(2014) Roy S. Herbst et al.   NATURE

Concerted effect of lymphopenia, viraemia and T-cell activation on Fas expression of peripheral B cells in HIV-1-infected patients

(2012) Bence Rethi et al.   AIDS

The impact of BVDV infection on adaptive immunity

(2012) Christopher C.L. Chase   BIOLOGICALS

The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome

(2012) Maximilian L. Würstle et al.   EXPERIMENTAL CELL RESEARCH

Apoptosis in Bovine Viral Diarrhea Virus (BVDV)–Induced Mucosal Disease Lesions

(2012) M. Hilbe et al.   VETERINARY PATHOLOGY

Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

(2011) F. Porichis et al.   BLOOD

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

(2011) Ruoning Wang et al.   IMMUNITY

Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism

(2011) Andrew N. Macintyre et al.   IMMUNITY

Impaired hepatitis B vaccine responses during chronic hepatitis C infection: Involvement of the PD-1 pathway in regulating CD4+ T cell responses

(2011) Jonathan P. Moorman et al.   VACCINE

Natural exposure of Dromedary camels in Sudan to infectious bovine rhinotracheitis virus (bovine herpes virus-1)

(2009) K.S. Intisar et al.   ACTA TROPICA

Negative Immune Regulator Tim-3 Is Overexpressed on T Cells in Hepatitis C Virus Infection and Its Blockade Rescues Dysfunctional CD4+ and CD8+ T Cells

(2009) L. Golden-Mason et al.   JOURNAL OF VIROLOGY

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

(2009) Nobuhiro Nakamoto et al.   PLoS Pathogens

Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization

(2008) Nobuhiro Nakamoto et al.   GASTROENTEROLOGY

Dynamic Programmed Death 1 Expression by Virus-Specific CD8 T Cells Correlates With the Outcome of Acute Hepatitis B

(2008) Zheng Zhang et al.   GASTROENTEROLOGY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Programmed death-1 as a factor in immune exhaustion and activation in HIV infection

(2008) Daniel E Kaufmann et al.   Current Opinion in HIV and AIDS