Article
Chemistry, Multidisciplinary
Ji-Soo Yun, Seon-Ae Hwangbo, Young-Gyu Jeong
Summary: Liposomes are microspheres that can encapsulate both hydrophilic and hydrophobic substances, making them important mediators in cosmetics and pharmaceuticals. This study developed a focused ultrasound method to produce nano-sized liposomes with better size control. Results showed that the liposomes produced using this method had a uniform size distribution and good stability.
Article
Engineering, Manufacturing
Bu Ping, Jin Huang, Fanbo Meng
Summary: This study develops a prediction model for the curing shrinkage behavior of inkjet 3D printed parts and proposes a method for compensating the print model graphic layers. The results show that the proposed model can accurately capture the curing shrinkage behavior and improve the accuracy of printed part dimensions.
JOURNAL OF MANUFACTURING PROCESSES
(2023)
Article
Materials Science, Multidisciplinary
Dongdong Zhang, Xiya He, Yu Liu, Fang Bai, Jinguo Wang
Summary: In TiCx/Cu composites fabricated via thermal explosion reaction combined with hot press in Cu-Ti-CNTs system, the increase of TiCx content led to improved compressive strength, yield strength and wear resistance, while decreasing strain f and electrical conductivities. The 30 vol.% TiCx/Cu composites exhibited the highest performance among the 25-30 vol.% TiCx/Cu composites.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Chemistry, Multidisciplinary
Zahra Rajabimashhadi, Rahim Naghizadeh, Ashkan Zolriasatein, Carola Esposito Corcione
Summary: Researchers successfully synthesized magnesium hydroxide nanoparticles with hexagonal structure and various morphologies including plate, flake, spherical, and disc shapes using the hydrothermal method by changing the precursor and surfactant.
Article
Astronomy & Astrophysics
Maximilian Stadelmaier
Summary: The origin and mass composition of ultrahigh-energy cosmic rays is a big open question in modern physics. The estimation of their mass involves comparing data with simulations using hadronic interaction models, but the models often disagree on certain aspects. However, there is good agreement in terms of the average depth of the shower maximum and the relative change in the number of produced muons based on the nuclear mass of the primary cosmic ray. Utilizing the similarities of these models, a method is proposed to estimate the primary mass of ultrahigh-energy cosmic rays based on the depth of the shower maximum and the number of produced muons.
ASTROPHYSICAL JOURNAL
(2023)
Article
Materials Science, Ceramics
Chao Yang, Zhihao Jin, Xianfu Chen, Jinhai Fan, Minghui Qiu, Kaiyun Fu, Yiqun Fan
Summary: In this study, pure tetragonal zirconia was successfully prepared by a modified hydrothermal method, exploring the effects of pH and glycerol content on the phase and morphology of the material. A high-performance ZrO2 ultrafiltration membrane was also prepared, showing good reproducibility and stability.
CERAMICS INTERNATIONAL
(2021)
Article
Engineering, Environmental
Yonglin Liu, Huayi Chen, Qiming Mo, Xingjian Yang, Jinjin Wang, Xueming Lin, Dongfang Shang, Yongtao Li, Yulong Zhang
Summary: This study prepared hydrogels with different polymerization degrees containing FeS nanoparticles of different sizes for the removal of Cd and TC in water. The size of nanoparticles decreased with increasing polymerization degree, and the incomplete crystallization of nanoparticles affected the removal efficiency.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Water Resources
Steffen Beck-Broichsitter, Zarghaam Haider Rizvi, Rainer Horn, Frank Wuttke
Summary: The presence of gravel in soils has an impact on the porosity, pore connectivity, pore size distribution and interfaces of the soil matrix. This study investigates the effect of relative volume of gravel on various properties of sandy and silty soils. The results show that the water retention curves of these soils can be well predicted by a weighting factor based on the relative volume of rock fragments.
JOURNAL OF HYDROLOGY AND HYDROMECHANICS
(2023)
Article
Multidisciplinary Sciences
M. R. Sazideh, M. H. Ehsani, M. M. Shahidi, H. Rezagholipour Dizaji
Summary: In this study, Tin (II) sulfide films were deposited on different substrates using the Physical Vapor Deposition method with Glancing Angle Deposition technique. The effects of substrate crystalline structure and deposition angles on the structure of SnS nano-plates were investigated. The phonons lifetime, atomic ratio, and morphological characteristics of the samples were analyzed. The formation of the second phase of Sn2S3 was confirmed, and the relationship between substrate roughness and SnS nano-sheets growth process was explained.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Manufacturing
Jizhuang Hui, Hao Zhang, Jingxiang Lv, Chul-Hee Lee, Chen Chen, Zhiqiang Yan, Jun jie Wang, Tao Peng, Lei Guo, Zhiguang Xu
Summary: This article investigates the effect of process parameters on the quality of conductive lines in inkjet printing. The results show that printing 5 layers with a platform temperature of 70 degrees C, a delay time of 12.2 ms, and a printing speed of 1139.39 mm/min can achieve low resistance and high aspect ratio conductive lines.
3D PRINTING AND ADDITIVE MANUFACTURING
(2023)
Article
Materials Science, Multidisciplinary
Haktan Sirali, Dogan Simsek, Dursun Ozyurek
Summary: The study investigated changes in microstructure, hardness, and wear performance of titanium-zirconium-molybdenum (TZM) alloys produced by mechanical alloying with different amounts of titanium (Ti). Increasing Ti content led to higher hardness but lower density in the alloys. The TZM alloy containing 0.55% Ti exhibited the highest hardness and the lowest wear weight loss under all loads.
METALS AND MATERIALS INTERNATIONAL
(2021)
Article
Materials Science, Multidisciplinary
Nahier Aldhafferi
Summary: In this paper, an extreme learning machine (ELM) computational intelligent method is proposed to predict the band gap energy of doped ZnSe nanostructured semiconductor using the material crystallite size and lattice parameter as descriptors. The developed ELM model with sine activation function shows superior performance compared to other models and its superiority is further justified through validation with external data. This is of great importance for quick characterization and tuning of energy gap of ZnSe nanostructured semiconductors.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Physics, Multidisciplinary
Yufeng Huang, Chaofeng Hou, Wei Ge
Summary: The significant self-heating effect severely affects the performance and reliability of nano-electronic devices. Therefore, understanding the process and mechanism of nano/microscale heat transfer is crucial for thermal management and design. A new Lattice Boltzmann Method (LBM) scheme with effective correction of phonon mean free path and relaxation time is proposed to study phonon heat transfer in silicon thin films and medium with defects. The proposed scheme generates more accurate results in heat conduction simulations of different nano/microscale structures.
Article
Geochemistry & Geophysics
Lijia Zhong, Fengyin Liu, Bo Wang, Zhao Yang, Dong Zhou
Summary: This paper investigates the pressure distribution law of muddy water with high silt content and proposes a pressure formula based on the test results. The formula is applicable in dam design and calculation.
Article
Optics
V. Lakshmi Savithri Vatsalya, G. Sunita Sundari, Ch. S. L. N. Sridhar, Ch. S. Lakshmi
Summary: Nanophased Ni0.65Zn0.35CuxFe(2-2x/3)O4 ferrites with varying copper dopant concentrations were synthesized using a hydrothermal method, and their structural and magnetic properties were characterized. The results show that these ferrites exhibit improved magnetic properties and have potential applications in high frequency, power, and biomedical fields.
Review
Pharmacology & Pharmacy
Chahinez Houacine, Iftikhar Khan, Sakib Saleem Yousaf
Summary: With a projected 23.6 million deaths per year by 2030, cardiovascular disease presents a significant need for novel compounds to prevent or treat the disease. Research on the use of resveratrol and its analogues as cardioprotective agents, as well as the role of nanotechnology in overcoming physicochemical limitations, is crucial in addressing this pressing issue.
CURRENT PHARMACEUTICAL DESIGN
(2021)
Article
Chemistry, Medicinal
Yamir Islam, Parinaz Ehtezazi, Andrew Cashmore, Elena Marinsalda, Andrew G. Leach, Christopher R. Coxon, Amos A. Fatokun, Darren W. Sexton, Iftikhar Khan, Georgios Zouganelis, James Downing, Stefano Pluchino, Muttuswamy Sivakumaran, Meritxell Teixido, Touraj Ehtezazi
Summary: The study investigated whether including MMP-9-sensitive sequences in brain-targeting nanoparticles could enhance BBB penetration during elevated MMP-9 levels, leading to increased transport across the BBB model when MMP-9 levels were elevated and the brain-targeting ligand was responsive to MMP-9.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Iftikhar Khan, Sozan Hussein, Chahinez Houacine, Sajid Khan Sadozai, Yamir Islam, Ruba Bnyan, Abdelbary Elhissi, Sakib Yousaf
Summary: This study aimed to develop and optimize NLC formulations in combination with various medical nebulizers and airflow rates for superior aerosolization performance. The results showed that the F10 formulation combined with the Air jet nebulizer exhibited the best performance in terms of particle size and drug deposition, making it the most suitable combination for delivering BDP-NLC formulations.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Review
Chemistry, Medicinal
Maria Apostolou, Sulaf Assi, Amos A. Fatokun, Iftikhar Khan
Summary: This study aimed to identify the effects of lipids on the physicochemical properties of Nanostructured Lipid Carriers (NLCs) through literature review. The size of solid lipid and its complexity tend to affect the particle size of the final formulation, while the ratio of solid to liquid lipid can influence the particle size and stability of NLCs. Entrapment efficiency is highly dependent on drug-lipid interaction and solubility, with no direct correlation found between lipids used and zeta potential.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Sakib Saleem Yousaf, Abdullah Isreb, Iftikhar Khan, Enosh Mewsiga, Abdelbary Elhissi, Waqar Ahmed, Mohamed A. Alhnan
Summary: This study compared the film formation properties of aqueous micro- and nano-suspensions of the enteric polymer Eudragit S100. Nano-suspensions produced thinner and more elastic films compared to micro-suspensions, without the need for alkalinising agents and high concentrations of plasticiser.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Iftikhar Khan, Rachel Needham, Sakib Yousaf, Chahinez Houacine, Yamir Islam, Ruba Bnyan, Sajid Khan Sadozai, Mohamed A. Elrayess, Abdelbary Elhissi
Summary: This study aimed to develop and optimize novel transfersome formulations for pulmonary drug delivery. Results showed that formulations F1 and F7, when combined with specific nebulizers, exhibited superior drug deposition and release characteristics in the respiratory tract.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Rachel Robson, Tilak Ginige, Saleh Mansour, Iftikhar Khan, Sulaf Assi
Summary: This article reviews the research on chemical analysis of latent fingerprints and discusses the identification methods for lipid and amino acid constituents. By using chromatographic and spectroscopic techniques, key biomarkers were identified, providing important complementary evidence in crime scene investigation.
Review
Pharmacology & Pharmacy
Alexandros Charitakis, Sulaf Assi, Sakib Yousaf, Iftikhar Khan
Summary: Urban pollution is a global problem that has a significant impact on public health and the environment. Aside from respiratory conditions, it also causes skin problems such as irritation, aging, and skin cancer. Toxic gases and particulate matter are the main pollutants that can attach to or penetrate the skin, leading to increased production of free radicals. A need for cosmetic products that can prevent and minimize the effects of pollutants on the skin is essential. Both intrinsic and extrinsic factors contribute to skin irritation and aging, and active ingredients with anti-pollutant properties can address these factors through various mechanisms.
CURRENT PHARMACEUTICAL DESIGN
(2022)
Review
Chemistry, Medicinal
Megan Smith, Matthew Roberts, Raida Al-Kassas
Summary: Osteomyelitis is a difficult-to-treat infection that is often caused by traditional implants. Recent attention has shifted to the design and fabrication of biodegradable implants, which are safer and more convenient than non-degradable systems. This review explores the latest research on antibiotic loaded biodegradable implants and compares their benefits and drawbacks to PMMA beads.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2022)
Review
Pharmacology & Pharmacy
Shea Stubbs, Sakib Yousaf, Iftikhar Khan
Summary: Bio-based surfactants, particularly those with carbohydrate head groups like alkyl polyglucosides (APGs) and sucrose esters (SEs), are considered safer, more affordable, and environmentally friendly alternatives to conventional surfactants. The use of green chemistry principles can further support the adoption of these bio-based surfactants in personal care products, aligning with global regulations for sustainability and safety. Industry efforts to implement and improve green chemistry principles at a commercial level are crucial in promoting the use of these novel surfactants.
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Chemistry, Medicinal
Marwan Algellay, Matthew Roberts, Lucy Bosworth, Satyajit D. Sarker, Amos A. Fatokun, Touraj Ehtezazi
Summary: This study explores the use of 3D printing to produce fast dissolving oral films (FDFs) and investigates the impact of adding chitosan micro-ribbons or cellulose microfibres on the mechanical properties of the films.
Article
Multidisciplinary Sciences
Iftikhar Khan, Ali Al-Hasani, Mohsin H. Khan, Aamir N. Khan, Fakhr-e-Alam, Sajid K. Sadozai, Abdelbary Elhissi, Jehanzeb Khan, Sakib Yousaf
Summary: The aim of this study was to prepare spray-dried proliposome (SDP) powder formulations for superior aerosolization performance. The study found that when using a combination of water and ethanol as dispersion medium (formulations F1-F5), superior formulation properties for pulmonary drug delivery were observed, irrespective of carrier type employed.
Article
Pharmacology & Pharmacy
Iftikhar Khan, Sakib Yousaf, Mohammad Najlah, Waqar Ahmed, Abdelbary Elhissi
Summary: This study aimed to develop and compare proliposome powder and proliposome tablet formulations for drug delivery from a Pari-LC Sprint nebulizer. The tablet formulations showed shorter sputtering times and higher drug output compared to powder formulations. Liposomes size was larger in the nebulizer reservoir, indicating aggregation/fusion, and all formulations exhibited more than 80% mass output.
JOURNAL OF PHARMACEUTICAL INVESTIGATION
(2021)