期刊
CHEMSUSCHEM
卷 10, 期 6, 页码 1210-1216出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cssc.201601469
关键词
carbon dioxide; catalysis; carboxylative cyclization; dual activation; zinc
资金
- National Key Research and Development Project [2016YFA0602900]
- National Natural Science Foundation of China
- Natural Science Foundation of Tianjin Municipality [16JCZDJC39900]
- Specialized Research Fund for the Doctoral Program of Higher Education [20130031110013]
- MOE Innovation Team of China [IRT13022]
- 111 Project of Ministry of Education of China [B06005]
Incorporation of CO2 into heterocyclic compounds (i.e., 2-oxazolidinones) under mild conditions, especially at atmospheric pressure still remains challenging. The mononuclear Zn-II complex ZnCl2(TBD)(2), where TBD=1,5,7-triazabicyclo[4.4.0]dec-5-ene, in this study was demonstrated as a robust catalyst for the carboxylative cyclization of propargylic amines with CO2 to exclusively afford various 2-oxazolidinones in excellent yields. Notably, the Zn-II catalytic species is readily generated insitu from ZnCl2 and TBD without pre-preparation and further isolation. Such a CO2 fixation protocol could proceed smoothly under atmospheric pressure at mild temperature in an atom economic and environmentally benign manner. (CNMR)-C-13 and control experiments were performed to explore the possible interaction between Zn-II and the carbon-carbon triple bond of propargylic amine. The dual catalytic role of the Zn catalyst to enhance O-nucleophilicity of the carbamate anion intermediate and activate the carbon-carbon triple bond is proposed based on mechanistic investigations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据