BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling
出版年份 2020 全文链接
标题
BET protein inhibitor JQ1 downregulates chromatin accessibility and suppresses metastasis of gastric cancer via inactivating RUNX2/NID1 signaling
作者
关键词
-
出版物
Oncogenesis
Volume 9, Issue 3, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-03-11
DOI
10.1038/s41389-020-0218-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma
- (2018) Jingyuan Wang et al. CANCER LETTERS
- Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming
- (2018) Ralph Stadhouders et al. NATURE GENETICS
- BRD4 regulates cellular senescence in gastric cancer cells via E2F/miR-106b/p21 axis
- (2018) Xingchen Dong et al. Cell Death & Disease
- Identification of Nidogen 1 as a lung metastasis protein through secretome analysis
- (2017) Maša Alečković et al. GENES & DEVELOPMENT
- Human prostate luminal cell differentiation requires NOTCH3 induction by p38-MAPK and MYC
- (2017) Sander B. Frank et al. JOURNAL OF CELL SCIENCE
- BRD4 promotes gastric cancer progression through the transcriptional and epigenetic regulation of c-MYC
- (2017) Mingchen Ba et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The interplay of epigenetic marks during stem cell differentiation and development
- (2017) Yaser Atlasi et al. NATURE REVIEWS GENETICS
- RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN
- (2017) Valentina Sancisi et al. NUCLEIC ACIDS RESEARCH
- CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer
- (2016) Mark L. McCleland et al. JOURNAL OF CLINICAL INVESTIGATION
- Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
- (2016) Shaokun Shu et al. NATURE
- Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
- (2016) M Ryan Corces et al. NATURE GENETICS
- BET inhibition as a new strategy for the treatment of gastric cancer
- (2016) Raquel C. Montenegro et al. Oncotarget
- RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression
- (2015) Karine A. Cohen-Solal et al. Molecular Cancer
- Transcriptional plasticity promotes primary and acquired resistance to BET inhibition
- (2015) Philipp Rathert et al. NATURE
- Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma
- (2014) Dhong Hyun Lee et al. INTERNATIONAL JOURNAL OF CANCER
- The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition
- (2014) Junwei Shi et al. MOLECULAR CELL
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
- (2014) Tomohiko Kanno et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- BET Bromodomain Inhibition of MYC-Amplified Medulloblastoma
- (2013) P. Bandopadhayay et al. CLINICAL CANCER RESEARCH
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
- (2013) Alexandre Puissant et al. Cancer Discovery
- BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
- (2012) C. J. Ott et al. BLOOD
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- Modulation of Epigenetic Targets for Anticancer Therapy: Clinicopathological Relevance, Structural Data and Drug Discovery Perspectives
- (2012) Federico Andreoli et al. CURRENT PHARMACEUTICAL DESIGN
- Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
- (2012) W. W. Lockwood et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now