Macromolecular and Small Molecular Crowding Have Similar Effects on α-Synuclein Structure

Structural disorder of monomeric α-synuclein persists in mammalian cells

(2016) Francois-Xavier Theillet et al.   NATURE

Effects of Polymer Hydrophobicity on Protein Structure and Aggregation Kinetics in Crowded Milieu

(2015) Leonid Breydo et al.   BIOCHEMISTRY

Role of solvent properties of aqueous media in macromolecular crowding effects

(2015) Luisa A. Ferreira et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu

(2015) Irina Kuznetsova et al.   MOLECULES

Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

(2014) Francois-Xavier Theillet et al.   CHEMICAL REVIEWS

Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments

(2014) Andrea Soranno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Observation of Protein Unfolded State Compaction in the Presence of Macromolecular Crowding

(2013) Therese Mikaelsson et al.   BIOPHYSICAL JOURNAL

19F NMR Spectroscopy as a Probe of Cytoplasmic Viscosity and Weak Protein Interactions in Living Cells

(2013) Yansheng Ye et al.   CHEMISTRY-A EUROPEAN JOURNAL

Effects of Macromolecular Crowding on the Conformational Ensembles of Disordered Proteins

(2013) Sanbo Qin et al.   Journal of Physical Chemistry Letters

Structural Characterization of Intrinsically Disordered Proteins by NMR Spectroscopy

(2013) Simone Kosol et al.   MOLECULES

From Sequence and Forces to Structure, Function, and Evolution of Intrinsically Disordered Proteins

(2013) Julie D. Forman-Kay et al.   STRUCTURE

Unexpected Effects of Macromolecular Crowding on Protein Stability

(2012) Laura A. Benton et al.   BIOCHEMISTRY

Counteracting chemical chaperone effects on the single-molecule  -synuclein structural landscape

(2012) A. C. M. Ferreon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macromolecular Crowding Remodels the Energy Landscape of a Protein by Favoring a More Compact Unfolded State

(2010) Jiang Hong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Detection of Transient Interchain Interactions in the Intrinsically Disordered Protein α-Synuclein by NMR Paramagnetic Relaxation Enhancement

(2010) Kuen-Phon Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding

(2010) Apratim Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Theory, Practice, and Applications of Paramagnetic Relaxation Enhancement for the Characterization of Transient Low-Population States of Biological Macromolecules and Their Complexes

(2009) G. Marius Clore et al.   CHEMICAL REVIEWS

Structural Reorganization of α-Synuclein at Low pH Observed by NMR and REMD Simulations

(2009) Kuen-Phon Wu et al.   JOURNAL OF MOLECULAR BIOLOGY

Using NMR to Distinguish Viscosity Effects from Nonspecific Protein Binding under Crowded Conditions

(2009) Conggang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural characterization of α-synuclein in an aggregation prone state

(2009) Min-Kyu Cho et al.   PROTEIN SCIENCE