Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing

Wounding triggers MIRO-1 dependent mitochondrial fragmentation that accelerates epidermal wound closure through oxidative signaling

(2020) Hongying Fu et al.   Nature Communications

Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors

(2018) Grace R. Anderson et al.   Nature Communications

Occluding junctions as novel regulators of tissue mechanics during wound repair

(2018) Lara Carvalho et al.   JOURNAL OF CELL BIOLOGY

Oxidative Stress Orchestrates Cell Polarity to Promote Embryonic Wound Healing

(2018) Miranda V. Hunter et al.   DEVELOPMENTAL CELL

FlyBase 2.0: the next generation

(2018) Jim Thurmond et al.   NUCLEIC ACIDS RESEARCH

Tension (re)builds: Biophysical mechanisms of embryonic wound repair

(2017) Teresa Zulueta-Coarasa et al.   MECHANISMS OF DEVELOPMENT

Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications

(2017) Susana Rovira-Llopis et al.   Redox Biology

Succinate promotes stem cell migration through the GPR91-dependent regulation of DRP1-mediated mitochondrial fission

(2017) So Hee Ko et al.   Scientific Reports

Silencing Drp1 inhibits glioma cells proliferation and invasion by RHOA/ ROCK1 pathway

(2016) Maojia Yin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial cytopathies

(2016) Ayman W. El-Hattab et al.   CELL CALCIUM

The actin cable is dispensable in directing dorsal closure dynamics but neutralizes mechanical stress to prevent scarring in the Drosophila embryo

(2016) Antoine Ducuing et al.   NATURE CELL BIOLOGY

Mitochondrial Dynamics and Metabolic Regulation

(2016) Timothy Wai et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Drosophila wing imaginal discs respond to mechanical injury via slow InsP3R-mediated intercellular calcium waves

(2016) Simon Restrepo et al.   Nature Communications

The Ins and Outs of Mitochondrial Calcium

(2015) T. Finkel et al.   CIRCULATION RESEARCH

Endocytosis-dependent coordination of multiple actin regulators is required for wound healing

(2015) Yutaka Matsubayashi et al.   JOURNAL OF CELL BIOLOGY

Polarized E-cadherin endocytosis directs actomyosin remodeling during embryonic wound repair

(2015) Miranda V. Hunter et al.   JOURNAL OF CELL BIOLOGY

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

(2015) Wei-ke Ji et al.   eLife

Coordination of Rho Family GTPase Activities to Orchestrate Cytoskeleton Responses during Cell Wound Repair

(2014) Maria Teresa Abreu-Blanco et al.   CURRENT BIOLOGY

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos

(2014) C. M. Lye et al.   DEVELOPMENT

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation

(2014) William Razzell et al.   DEVELOPMENT

C. elegans Epidermal Wounding Induces a Mitochondrial ROS Burst that Promotes Wound Repair

(2014) Suhong Xu et al.   DEVELOPMENTAL CELL

Mitochondrial ROS Regulates Cytoskeletal and Mitochondrial Remodeling to Tune Cell and Tissue Dynamics in a Model for Wound Healing

(2014) Sonia Muliyil et al.   DEVELOPMENTAL CELL

A NovelMitoTimerReporter Gene for Mitochondrial Content, Structure, Stress, and Damagein Vivo

(2014) Rhianna C. Laker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Toll/NF-κB signaling pathway is required for epidermal wound repair inDrosophila

(2014) Lara Carvalho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium Flashes Orchestrate the Wound Inflammatory Response through DUOX Activation and Hydrogen Peroxide Release

(2013) William Razzell et al.   CURRENT BIOLOGY

Interplay between the Dividing Cell and Its Neighbors Regulates Adherens Junction Formation during Cytokinesis in Epithelial Tissue

(2013) Sophie Herszterg et al.   DEVELOPMENTAL CELL

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission

(2013) Nina Huber et al.   EMBO REPORTS

Coordinated waves of actomyosin flow and apical cell constriction immediately after wounding

(2013) Marco Antunes et al.   JOURNAL OF CELL BIOLOGY

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Inositol kinase and its product accelerate wound healing by modulating calcium levels, Rho GTPases, and F-actin assembly

(2013) X. Soto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Cytoskeleton responses in wound repair

(2012) Maria Teresa Abreu-Blanco et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transgenic Control of Mitochondrial Fission Induces Mitochondrial Uncoupling and Relieves Diabetic Oxidative Stress

(2012) C. A. Galloway et al.   DIABETES

Drosophila embryos close epithelial wounds using a combination of cellular protrusions and an actomyosin purse string

(2012) M. T. Abreu-Blanco et al.   JOURNAL OF CELL SCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Mitochondria as sensors and regulators of calcium signalling

(2012) Rosario Rizzuto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo

(2012) Brian DuBoff et al.   NEURON

Mitochondrial dynamics regulates migration and invasion of breast cancer cells

(2012) J Zhao et al.   ONCOGENE

Genetic Analysis in Drosophila Reveals a Role for the Mitochondrial Protein P32 in Synaptic Transmission

(2012) Andrew Lutas et al.   G3-Genes Genomes Genetics

A Gαq-Ca2+ Signaling Pathway Promotes Actin-Mediated Epidermal Wound Closure in C. elegans

(2011) Suhong Xu et al.   CURRENT BIOLOGY

Regulatory Domain Selectivity in the Cell-Type Specific PKN-Dependence of Cell Migration

(2011) Sylvie Lachmann et al.   PLoS One

Rho-kinase/ROCK: A key regulator of the cytoskeleton and cell polarity

(2010) Mutsuki Amano et al.   Cytoskeleton

Integration of Single and Multicellular Wound Responses

(2009) Andrew G. Clark et al.   CURRENT BIOLOGY

Genetic Screen in Drosophila melanogaster Uncovers a Novel Set of Genes Required for Embryonic Epithelial Repair

(2009) I. Campos et al.   GENETICS

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

(2009) Naotada Ishihara et al.   NATURE CELL BIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Ca2+ Signaling, Mitochondria and Cell Death

(2008) Paolo Pinton et al.   CURRENT MOLECULAR MEDICINE

Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closure

(2008) T. H. Millard et al.   DEVELOPMENT

Mitochondria: The Hub of Cellular Ca2+ Signaling

(2008) György Szabadkai et al.   PHYSIOLOGY