Article
Engineering, Environmental
Shijuan Wu, Zijie Zhou, Lin Zhu, Limin Zhong, Yixuan Dong, Gejiao Wang, Kaixiang Shi
Summary: In this study, a highly cadmium-resistant bacterium, Pseudomonas sp. B7, was isolated and its mechanism of Cd(II) immobilization and resistance was explored. The study revealed that the CadW protein is involved in the bacterium's resistance to Cd(II) and enhances intracellular Cd(II) accumulation.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Yuting Meng, Jing Huang, Huaikang Jing, Qi Wu, Renfang Shen, Xiaofang Zhu
Summary: Exogenous ABA can alleviate Cd toxicity in Arabidopsis thaliana by reducing Cd uptake, translocation, and accumulation, promoting Cd chelation and efflux, and this pathway might be regulated by the transcription factor ABI4 in the ABA signaling pathway.
Article
Environmental Sciences
Alondra A. Cortes Tellez, Sebastian Sanchez-Fortun, Ana Sanchez-Fortun, Martha-Estrella Garcia-Perez, Luis Chacon-Garcia, M. Carmen Bartolome
Summary: This study demonstrates that Dc(RCd100) exhibits resistance compared to Dc1M(wt) in individual metal exposures, with different levels of sensitivity to various divalent metals. The Combination Index method is highlighted as an effective way to predict binary metal interactions in wild-type and Cd-resistant strains of D.chlorelloides, showing potential for bioremediation of metal-contaminated effluents.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Engineering, Environmental
Diwu Fan, Yong Sun, Moxian Chen, Yongli Zhu, Evgenios Agathokleous, Fuyuan Zhu, Jiangang Han
Summary: This study aimed to identify and verify key genes in regulating Cd-induced hormesis in Arabidopsis thaliana. The results showed that hormesis occurred at certain concentrations of Cd, and the antioxidant defense system and photosynthesis system played roles in hormesis. The key gene ABF1 in the metabolic pathway of abscisic acid was identified and found to be essential for Cd-induced hormesis.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Ana C. C. Silva, Pedro Rocha, Dulce Geraldo, Ana Cunha, Juan Antelo, Jose P. Pinheiro, Sarah Fiol, Fatima Bento
Summary: This study demonstrates the use of Cd2+ as a reactivity probe for compost extracts of fulvic acids, humic acids, and dissolved organic matter. The HA extract showed the highest reactivity among the extracts. Furthermore, the reactivity variation was the largest for HA, followed by FA and DOM extracts. A parameter, equivalent mass of fertiliser (m(EF)), was used to calculate the compost quality and compared with uncomposted organic fertiliser. The significance of this parameter was verified through a correlation analysis between binding extent and the effect of compost application on lettuce crop growth.
Article
Plant Sciences
Anja T. Fuglsang, Michael Palmgren
Summary: Plant plasma membrane H+-ATPases and Ca2+-ATPases are crucial for maintaining low cytoplasmic concentrations of H+ and Ca2+ respectively, essential for plant growth and development. They are finely regulated in response to external stimuli and physiological adaptations.
Article
Materials Science, Multidisciplinary
Abderrahmane Naas, Abdelmounaim Chetoui, Lahouari Ghalouci, Mohamed Redha Khelladi
Summary: This paper investigates the physicochemical properties of pure Cd(OH)(2) and Cd(OH)(2)-CdO composite materials in depth. The cadmium sulfate octahydrate (3CdSO(4).8H(2)O) is used as a precursor for the first time in this work and never been used in previous works involving cadmium-based materials. Additionally, we present the first synthesis of Cd(OH)(2)-CdO by pneumatic spray pyrolysis deposition technique. The molarity has a clear impact on the formation of pure Cd(OH)(2) or Cd(OH)(2)-CdO phase mixture, and the films show high transparency and low resistivity.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2022)
Article
Environmental Sciences
Zhoujie Wang, Huadong Tian, Jing Liu, Jingyi Wang, Qingye Lu, Lei Xie
Summary: Adsorption of Cd(II) on serpentine was investigated under typical environment conditions, involving common environmental anions and cations. The adsorption was negligibly affected by anion type, but was specifically modulated by cations. Mono- and divalent cations enhanced the adsorption by weakening electrostatic double layer repulsion, while trivalent cations suppressed the adsorption due to competitive adsorption. Fe3+ and Al3+ prevented Cd(II) adsorption by binding surface active sites, forming more stable inner-sphere complexes. This study provides insights into the influence of interfacial ion specificity on Cd(II) adsorption in terrestrial and aquatic environments.
ENVIRONMENTAL POLLUTION
(2023)
Article
Biochemistry & Molecular Biology
Mahsa Modareszadeh, Ramin Bahmani, DongGwan Kim, Seongbin Hwang
Summary: Over-expression of the CAX3 gene enhances Cd tolerance in Arabidopsis by decreasing ROS levels, activating antioxidant enzymes, and regulating cytoplasmic Ca spikes.
PLANT MOLECULAR BIOLOGY
(2021)
Article
Microbiology
Ildiko Vig, Zsigmond Benko, Barnabas Cs. Gila, Zoltan Palczert, Agnes Jakab, Fruzsina Nagy, Marton Miskei, Mi-Kyung Lee, Jae-Hyuk Yu, Istvan Pocsi, Tamas Emri
Summary: P1B-type ATPases are important Cd2+/Cu2+ pumps in Aspergillus species, and their deletion increases sensitivity to Zn2+, Fe2+, or oxidative stress-induced by menadione sodium bisulfite and Fe3+. Heterologous expression of A. fumigatus PcaA enhances tolerance to Cd(2+) or Zn2+ stress in S. cerevisiae, while CrpA protects against oxidative stress and Fe2+ susceptibility indirectly. These P1B-type ATPases play a crucial role in protecting fungal cells from various stresses and may be potential drug targets.
MICROBIOLOGY SPECTRUM
(2023)
Article
Environmental Sciences
Hiroshi Kudo, Chihiro Inoue, Kazuki Sugawara
Summary: The study demonstrated the accumulation of Cd by Arabidopsis halleri ssp. gemmifera, with an increase in biomass, Cd, and Zn concentration in the plant over 103 days of experimentation. Soil Cd concentration significantly decreased, and the material balance showed Cd uptake by the plant and decrement from the soil ranging from 63.3% to 83.7% in each growth stage. Analysis revealed stable water-eluted and exchangeable forms of Cd, with a decrease in the fraction extracted with 0.1 M HCl, indicating its non-bioavailability.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Qin Yao, Weiping Li, Ying Liu, Yiran Cheng, Xue Xiao, Dan Long, Jian Zeng, Dandan Wu, Lina Sha, Xing Fan, Houyang Kang, Haiqin Zhang, Yonghong Zhou, Yi Wang
Summary: FeCl3 and Fe-2(SO4)(3) can reduce Cd accumulation in wheat, and the most effective treatment is 50 μM FeCl3.
ENVIRONMENTAL POLLUTION
(2023)
Article
Plant Sciences
Chunying Wang, Ziqiang Gao, Yang Shi, Xiaoting Qi
Summary: Molecular, biochemical, and genetic experiments demonstrate that metal-responsive elements (MREs), initially identified in animals, confer the cadmium transcriptional response in Arabidopsis, thus providing deep functional insights of MREs in plants.
Article
Plant Sciences
Ziwei Zhang, Sheliang Wang, Jun Wang, Cheng Zhang, Dong Liu, Chuang Wang, Fangsen Xu
Summary: This study investigated the role of LPR1 in Cd stress and found that the overexpression of LPR1 resulted in reduced primary root lengths, fresh weights, lengths of the non-root hair zone, and chlorophyll contents. It also triggered ROS bursts and reduced the entry of available iron into the cell, which induced the expression of IRT1 and exacerbated the Cd influx into plants. These findings highlight the pathway of LPR1-mediated plant response to Cd toxicity stress through the regulation of ROS and Fe homeostasis.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Environmental Sciences
Carla Calixta Calva Jimenez, Liliana Valentina Pinedo Fernandez, Cristiano E. Rodrigues Reis
Summary: This study evaluated the effect of amendments on cocoa seedlings and found that the application of lime and charcoal can reduce the migration of cadmium towards the seedlings, and the combination of lime and charcoal can prevent the presence of cadmium in the seedlings.
Article
Biochemistry & Molecular Biology
T. P. Ajeesh Krishna, T. Maharajan, S. Antony Ceasar
Summary: More than three billion people worldwide suffer from health issues caused by a lack of zinc and iron, leading to malnutrition. Biofortification is a potential solution to this problem, but understanding the molecular mechanisms involved is challenging. This review discusses the role of membrane transporters in the uptake, transport, storage, and redistribution of zinc and iron in plants, particularly in seed biofortification. The information provided will help plant breeders and molecular biologists understand the importance and implications of membrane transporters for seed biofortification.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Review
Agronomy
Kasinathan Rakkammal, Theivanayagam Maharajan, Stanislaus Antony Ceasar, Manikandan Ramesh
Summary: Biostimulants are products that reduce fertilizer requirements, stimulate plant growth, and protect crops from abiotic stress by increasing tolerance. They have various effects on plant growth, including promoting growth, enhancing nutrient absorption and utilization, increasing photosynthetic activity, and improving tolerance to biotic and abiotic stressors.
CEREAL RESEARCH COMMUNICATIONS
(2023)
Article
Plant Sciences
S. Antony Ceasar
Summary: Foxtail millet, a fully annotated C4 model cereal, has genomic resources that are helpful in understanding and improving nutrient transport in other cereals.
PLANT GROWTH REGULATION
(2023)
Review
Biochemistry & Molecular Biology
V. Edwin Hillary, S. Antony Ceasar
Summary: The CRISPR/Cas system has revolutionized life science research by providing powerful tools for manipulating, detecting, imaging, and annotating DNA or RNA sequences. This review focuses on the two classes of the CRISPR/Cas system, as well as the mechanisms and applications of Cas proteins, including Cas12, Cas13, and Cas14. The review also discusses the pros and cons of various Cas proteins and their recent applications, such as detecting SARS-CoV-2.
MOLECULAR BIOTECHNOLOGY
(2023)
Article
Plant Sciences
Theivanayagam Maharajan, Thumadath Palayullaparambil Ajeesh Krishna, Stanislaus Antony Ceasar, Savarimuthu Ignacimuthu
Summary: Zinc deficiency has negative effects on the growth, biomass, and yield of sorghum. It also alters the expression of ZIP family transporter genes in both shoot and root tissues. The study found that certain SbZIP genes were highly induced by deficient zinc, and that these genes are closely related to the ZmZIP family of maize. The conservation of functional residues in the SbZIP family transporters suggests their importance in zinc uptake and transport. This research provides insights for improving zinc-use efficiency in sorghum.
Article
Plant Sciences
Kasinathan Rakkammal, Theivanayagam Maharajan, R. N. Shriram, P. S. Jeevan Ram, Stanislaus Antony Ceasar, Manikandan Ramesh
Summary: Drought is a dangerous abiotic stress that negatively affects the growth, development, and yield of major cereals like finger millet. This study conducted physiological and molecular analyses to examine the responses of ten finger millet genotypes to drought. The results showed that drought significantly reduced the physiological traits of the genotypes, but the tolerant genotype (IC 87469) exhibited higher chlorophyll pigment contents, antioxidant enzyme activities, and proline accumulation compared to the susceptible genotype (IC 49940). The study also identified and analyzed four classical drought-responsive genes from the finger millet genome sequence. These findings provide valuable insights for future biotechnological approaches to improve drought tolerance in finger millet.
SOUTH AFRICAN JOURNAL OF BOTANY
(2023)
Article
Agronomy
Krishnananda Ingle, Mangesh Moharil, Santosh Gahukar, Praveen Jadhav, Rameshwar Ghorade, Niranjan Thakur, Krishna Kasanaboina, Stanislaus Antony Ceasar
Summary: This study assessed the pollen fertility and in vitro pollen germination of sorghum male and female lines and F-1 hybrids using multivariate analysis. The findings showed significant genetic divergence in the hybrids and identified genotypes with high pollen fertility for the breeding of high-yielding hybrids. The study also revealed the restoration behavior of pollen fertility in the hybrids, which will facilitate the identification of potential restorers in sorghum breeding programs.
Review
Multidisciplinary Sciences
Varghese Edwin Hillary, Stanislaus Antony Ceasar
Summary: SARS-CoV-2 is a highly contagious and pathogenic virus that causes COVID-19, an acute respiratory disease. Novel mutated variants of SARS-CoV-2 have emerged and are a global health concern. Scientists are researching antiviral drugs and vaccines to combat the disease. This review summarizes the dynamic transmission of SARS-CoV-2, its variants, and the antiviral drugs and vaccines used against it, aiming to provide knowledge for the development of efficient vaccines against future SARS-CoV-2 strains.
Review
Multidisciplinary Sciences
Sathiyabama Rajiv Gandhi, Gopalsamy Rajiv Gandhi, Poovathumkal James Antony, Varghese Edwin Hillary, Stanislaus Antony Ceasar, Govindasamy Hariharan, Yi Liu, Ricardo Queiroz Gurgel, Jullyana de Souza Siqueira Quintans, Lucindo Jose Quintans Junior
Summary: This study systematically reviewed the literature on the therapeutic potentials and molecular mechanisms of the Miconia genus, including in vivo and in vitro studies. The results showed that Miconia species have various biological activities such as anti-inflammatory, anticancer, analgesic, antibacterial, cytotoxic, and antioxidant properties. Miconia albicans and Miconia rubiginosa were the most frequently studied species and showed significant efficacy in treating pain and inflammation.
Article
Agronomy
Kasinathan Rakkammal, Subramani Pandian, Theivanayagam Maharajan, Stanislaus Antony Ceasar, Soo-In Sohn, Manikandan Ramesh
Summary: Salt stress is a major abiotic stress that has negative effects on plant growth, development, and yield worldwide. Humic acid, a natural component of soil and biostimulant, has the potential to effectively alleviate abiotic stress in plants. However, the physiological mechanism underlying humic acid-alleviated salt stress in finger millet remains unknown.
CEREAL RESEARCH COMMUNICATIONS
(2023)
Review
Plant Sciences
Muthusamy Ramakrishnan, Mingbing Zhou, Stanislaus Antony Ceasar, Doulathunnisa Jaffar Ali, Theivanayagam Maharajan, Kunnummal Kurungara Vinod, Anket Sharma, Zishan Ahmad, Qiang Wei
Summary: Somatic embryogenesis is a complex process regulated by genetic and epigenetic factors, including DNA and histone modifications, as well as miRNA regulation. These regulations influence the transition of somatic cells and the development of embryos, with the potential for somatic cell regeneration.
PLANT CELL REPORTS
(2023)
Article
Plant Sciences
T. P. Ajeesh Krishna, T. Maharajan, S. Antony Ceasar, S. Ignacimuthu
Summary: This study analyzed the changes in phenotypic, seed yield, biochemical, and molecular aspects of seven millets under different levels of zinc supply. The results showed that the phenotypic traits of all seven millets responded better to zinc concentrations of 0.50 to 2 μM compared to zinc deficiency (0.05 μM). Under zinc deficiency conditions, the millets had lower zinc contents in both the leaf and root tissues, increased antioxidant enzyme activity in the leaves, and increased root-related traits. The molecular studies indicated that higher expression levels of root-specific genes correlated with root phenotypic traits.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2023)
Article
Plant Sciences
Theivanayagam Maharajan, Thumadath Palayullaparambil Ajeesh Krishna, Jayabalan Shilpha, Stanislaus Antony Ceasar
Summary: Deficiencies of phosphorus and zinc have a significant impact on finger millet, affecting plant biomass, root hair modification, nutrient uptake, and molecular responses. While phosphorus deficiency has a greater effect on biomass reduction compared to zinc deficiency, the combined deficiency of both phosphorus and zinc leads to an increase in root hair length and density. Phosphorus deficiency promotes zinc uptake, and zinc deficiency promotes phosphorus uptake. This study provides valuable insights for better management of phosphorus and zinc deficiency in finger millet.
Review
Tropical Medicine
Gopalsamy Rajiv Gandhi, Alan Bruno Silva Vasconcelos, Poovathumkal James Antony, Monalisa Martins Montalvao, Mariana Nobre Farias de Franca, Varghese Edwin Hillary, Stanislaus Antony Ceasar, Dan Liu
Summary: This review focuses on the biological activities of shikimic acid and its derivatives, such as antibacterial and antiviral properties. It presents the sources and biosynthesis of shikimic acid and its derivatives, and discusses their diverse bioactivities including antioxidant, antiviral, anti-inflammatory, antibacterial, hypolipidemic, bone protective, skin protective, neuroprotective, and antidiabetic activities. The related molecular mechanisms are also highlighted. Overall, the wide range of bioactivities of shikimic acid and its derivatives suggests the need for further exploration of their potential in the prevention and treatment of certain diseases.
ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE
(2023)
Review
Biochemistry & Molecular Biology
T. P. Adarsh Krishna, T. P. Ajeesh Krishna, Baldev Edachery, S. Antony Ceasar
Summary: Guggulsterone, a phytosteroid derived from Commiphora wightii, has attracted attention for its excellent chemical biology potential. This review provides an update on the improvements in chemical synthesis and structural modification of guggulsterone, including the activities of modified derivatives.
RSC MEDICINAL CHEMISTRY
(2023)
