Repurposing Ellipticine Hydrochloride to Combat Colistin-Resistant Extraintestinal Pathogenic E. coli (ExPEC)

Identification of an IKKβ inhibitor for inhibition of inflammation in vivo and in vitro

(2019) Qi Chen et al.   PHARMACOLOGICAL RESEARCH

New therapy from old drugs: synergistic bactericidal activity of sulfadiazine with colistin against colistin-resistant bacteria, including plasmid-mediated colistin-resistant mcr-1 isolates

(2018) Liliane Okdah et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Comparison of two docking methods for peptide-protein interactions

(2018) Qiuying Yu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

(2018) Zheng Pang et al.   BIOTECHNOLOGY ADVANCES

Cerebrospinal fluid pro-inflammatory cytokines differentiate parkinsonian syndromes

(2018) C. Starhof et al.   Journal of Neuroinflammation

Survival after multiple traumas is associated with improved outcomes from gram-negative sepsis: Clinical and experimental evidence

(2017) Eleftherios Mandragos et al.   JOURNAL OF INFECTION

Cephalosporin-Glycopeptide Combinations for Use against Clinical Methicillin-Resistant Staphylococcus aureus Isolates: Enhanced In vitro Antibacterial Activity

(2017) Hung-Jen Tang et al.   Frontiers in Microbiology

The Disulfide Bond of the Peptide Thanatin Is Dispensible for Its Antimicrobial ActivityIn VivoandIn Vitro

(2016) Bo Ma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

First Description ofmcr-1-Mediated Colistin Resistance in Human Infections Caused by Escherichia coli in Latin America

(2016) Melina Rapoport et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of Plasmid-Mediated Colistin Resistance Genemcr-1in a Clinical Escherichia coli Isolate from Egypt

(2016) Shimaa S. Elnahriry et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

First Detection of themcr-1Colistin Resistance Gene in Escherichia coli in Italy

(2016) Antonio Cannatelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effective antimicrobial activity of Cbf-14, derived from a cathelin-like domain, against penicillin-resistant bacteria

(2016) Lingman Ma et al.   BIOMATERIALS

Inhibition of human DNA topoisomerase IIα by two novel ellipticine derivatives

(2016) Kendra R. Vann et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Emergence of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae

(2016) Hong Du et al.   LANCET INFECTIOUS DISEASES

Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study

(2016) Yi-Yun Liu et al.   LANCET INFECTIOUS DISEASES

Colistin in Pig Production: Chemistry, Mechanism of Antibacterial Action, Microbial Resistance Emergence, and One Health Perspectives

(2016) Mohamed Rhouma et al.   Frontiers in Microbiology

Transcriptomic analysis of colistin-susceptible and colistin-resistant isolates identifies genes associated with colistin resistance in Acinetobacter baumannii

(2015) Y.K. Park et al.   CLINICAL MICROBIOLOGY AND INFECTION

Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections

(2015) Shankar Thangamani et al.   Scientific Reports

The Anticancer Drug Ellipticine Activated with Cytochrome P450 Mediates DNA Damage Determining Its Pharmacological Efficiencies: Studies with Rats, Hepatic Cytochrome P450 Reductase Null (HRN™) Mice and Pure Enzymes

(2014) Marie Stiborová et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Membrane Active Vancomycin Analogues: A Strategy to Combat Bacterial Resistance

(2014) Venkateswarlu Yarlagadda et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cationic amphiphilic alpha-helical peptides for the treatment of carbapenem-resistant Acinetobacter baumannii infection

(2012) Yuan Huang et al.   BIOMATERIALS

Transposons and integrons in colistin-resistant clones of Klebsiella pneumoniae and Acinetobacter baumannii with epidemic or sporadic behaviour

(2012) Sonia M. Arduino et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Comparative in vitro and in vivo antimalarial activity of the indole alkaloids ellipticine, olivacine, cryptolepine and a synthetic cryptolepine analog

(2012) L.F. Rocha e Silva et al.   PHYTOMEDICINE

Colistin Resistance in Acinetobacter baumannii Is Mediated by Complete Loss of Lipopolysaccharide Production

(2010) J. H. Moffatt et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

Spread of colistin resistant non-mucoid Pseudomonas aeruginosa among chronically infected Danish cystic fibrosis patients

(2008) Helle Krogh Johansen et al.   Journal of Cystic Fibrosis