TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse

(2019) Pedro Guedes-Dias et al.   CURRENT BIOLOGY

Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder

(2019) Hyunpil Lee et al.   Translational Psychiatry

Myelinated axons fail to develop properly in a genetically authentic mouse model of Charcot-Marie-Tooth disease type 2E

(2018) Eunjoo Lancaster et al.   EXPERIMENTAL NEUROLOGY

Rapid and Specific Immunomagnetic Isolation of Mouse Primary Oligodendrocytes

(2018) Rafael E. Flores-Obando et al.   Jove-Journal of Visualized Experiments

Motor protein binding and mitochondrial transport are altered by pathogenic TUBB4A variants

(2018) Franca Vulinovic et al.   HUMAN MUTATION

Lineage tracing reveals dynamic changes in oligodendrocyte precursor cells following cuprizone-induced demyelination

(2017) Emily G. Baxi et al.   GLIA

TUBB4A mutations result in specific neuronal and oligodendrocytic defects that closely match clinically distinct phenotypes

(2017) Julian Curiel et al.   HUMAN MOLECULAR GENETICS

Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum

(2017) Balint Nagy et al.   PLOS BIOLOGY

Adult oligodendrocyte progenitor cells – Multifaceted regulators of the CNS in health and disease

(2016) Anthony Fernandez-Castaneda et al.   BRAIN BEHAVIOR AND IMMUNITY

TUBB4A-related hypomyelinating leukodystrophy: New insights from a series of 12 patients

(2016) Davide Tonduti et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

KymographClear and KymographDirect: two tools for the automated quantitative analysis of molecular and cellular dynamics using kymographs

(2016) Pierre Mangeol et al.   MOLECULAR BIOLOGY OF THE CELL

A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease

(2016) Jayden A. Clark et al.   Frontiers in Cellular Neuroscience

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

(2016) Danielle N. Feather-Schussler et al.   Jove-Journal of Visualized Experiments

NovelTUBB4Amutations and expansion of the neuroimaging phenotype of hypomyelination with atrophy of the basal ganglia and cerebellum (H-ABC)

(2014) Carlos Ferreira et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Hypomyelination with atrophy of the basal ganglia and cerebellum: further delineation of the phenotype and genotype–phenotype correlation

(2014) Eline M. Hamilton et al.   BRAIN

Changes in NG2 cells and oligodendrocytes in a new model of intraspinal hemorrhage

(2014) F. Rezan Sahinkaya et al.   EXPERIMENTAL NEUROLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Expansion of the spectrum of TUBB4A-related disorders: a new phenotype associated with a novel mutation in the TUBB4A gene

(2014) Lubov Blumkin et al.   NEUROGENETICS

TUBB4A de novo mutations cause isolated hypomyelination

(2014) A. Pizzino et al.   NEUROLOGY

Expanding the phenotypic spectrum of TUBB4A-associated hypomyelinating leukoencephalopathies

(2014) S. Miyatake et al.   NEUROLOGY

Clinical Exome Sequencing Identifies a Novel TUBB4A Mutation in a Child With Static Hypomyelinating Leukodystrophy

(2014) Shawn M. Purnell et al.   PEDIATRIC NEUROLOGY

A De Novo Mutation in the β-Tubulin Gene TUBB4A Results in the Leukoencephalopathy Hypomyelination with Atrophy of the Basal Ganglia and Cerebellum

(2013) Cas Simons et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis

(2013) Shin H Kang et al.   NATURE NEUROSCIENCE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Mutations in the autoregulatory domain of β-tubulin 4a cause hereditary dystonia

(2012) Joshua Hersheson et al.   ANNALS OF NEUROLOGY

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

Microtubule dysfunction precedes transport impairment and mitochondria damage in MPP+-induced neurodegeneration

(2010) Daniele Cartelli et al.   JOURNAL OF NEUROCHEMISTRY

Slowly Progressive Axonal Degeneration in a Rat Model of Chronic, Nonimmune-Mediated Demyelination

(2010) Alastair Wilkins et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A rotarod test for evaluation of motor skill learning

(2010) Hiromi Shiotsuki et al.   JOURNAL OF NEUROSCIENCE METHODS

The life, death, and replacement of oligodendrocytes in the adult CNS

(2008) Dana M. McTigue et al.   JOURNAL OF NEUROCHEMISTRY