Artesunate: could be an alternative drug to chloroquine in COVID-19 treatment?

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

Chloroquine for the 2019 novel coronavirus SARS-CoV-2

(2020) Philippe Colson et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Coronavirus infections and immune responses

(2020) Geng Li et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools

(2020) Yajing Fu et al.   VIROLOGICA SINICA

The Use of Antimalarial Drugs against Viral Infection

(2020) Sarah D’Alessandro et al.   Microorganisms

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

(2020) Hin Chu et al.   CLINICAL INFECTIOUS DISEASES

New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?

(2020) Christian A. Devaux et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality

(2020) Chi Zhang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Middle East Respiratory Syndrome Coronavirus-Encoded Accessory Proteins Impair MDA5-and TBK1-Mediated Activation of NF-��B

(2019) Jeong Yoon Lee et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

(2018) Javier Canton et al.   PLoS Pathogens

Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

(2017) S. J. Anthony et al.   mBio

Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

(2017) Ben Hu et al.   PLoS Pathogens

Artesunate demonstrates in vitro synergism with several antiviral agents against human cytomegalovirus

(2016) Emilien Drouot et al.   ANTIVIRAL THERAPY

Artesunate attenuated progression of atherosclerosis lesion formation alone or combined with rosuvastatin through inhibition of pro-inflammatory cytokines and pro-inflammatory chemokines

(2016) Weiwei Jiang et al.   PHYTOMEDICINE

Artesunate, an anti-malarial drug, has a potential to inhibit HCV replication

(2016) Rongjuan Dai et al.   VIRUS GENES

Antiviral Effects of Artesunate on JC Polyomavirus Replication in COS-7 Cells

(2014) Biswa Nath Sharma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of the immunosuppressive activity of artesunate in vitro and in vivo

(2013) Tan Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of NF- B-Mediated Inflammation in Severe Acute Respiratory Syndrome Coronavirus-Infected Mice Increases Survival

(2013) M. L. DeDiego et al.   JOURNAL OF VIROLOGY

Artemisinin Analogues as Potent Inhibitors of In Vitro Hepatitis C Virus Replication

(2013) Susan Obeid et al.   PLoS One

The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte

(2009) Ya He et al.   RHEUMATOLOGY INTERNATIONAL

The Antiviral Activities of Artemisinin and Artesunate

(2008) Thomas Efferth et al.   CLINICAL INFECTIOUS DISEASES