Mitochondrial reactive oxygen species as major effectors of antimicrobial immunity

Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO

(2019) Marc Herb et al.   Science Signaling

Reactive species and pathogen antioxidant networks during phagocytosis

(2019) Lucía Piacenza et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mitochondrial Reactive Oxygen Species Contribute to Pathological Inflammation During Influenza A Virus Infection in Mice

(2019) Eunice E. To et al.   ANTIOXIDANTS & REDOX SIGNALING

TNF Induces Pathogenic Programmed Macrophage Necrosis in Tuberculosis through a Mitochondrial-Lysosomal-Endoplasmic Reticulum Circuit

(2019) Francisco J. Roca et al.   CELL

Oxidative responses and fungal infection biology

(2018) Adilia Warris et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mitochondrial reactive oxygen species regulate the induction of CD8+ T cells by plasmacytoid dendritic cells

(2018) Marine Oberkampf et al.   Nature Communications

Mitochondria-Derived Vesicles Deliver Antimicrobial Reactive Oxygen Species to Control Phagosome-Localized Staphylococcus aureus

(2018) Basel H. Abuaita et al.   Cell Host & Microbe

Reactive Oxygen Species Localization Programs Inflammation to Clear Microbes of Different Size

(2017) Annika Warnatsch et al.   IMMUNITY

The role of mitochondrial ROS in antibacterial immunity

(2017) Boris Pinegin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis

(2017) Pia Rademann et al.   Oxidative Medicine and Cellular Longevity

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense

(2016) Johan Garaude et al.   NATURE IMMUNOLOGY

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity

(2015) Jing Geng et al.   NATURE IMMUNOLOGY

Genetic disorders coupled to ROS deficiency

(2015) Sharon O’Neill et al.   Redox Biology

ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use

(2014) Rebeca Acín-Pérez et al.   Cell Metabolism

Mitochondrial anti-oxidant protects IEX-1 deficient mice from organ damage during endotoxemia

(2014) Haley Ramsey et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species

(2013) Francisco J. Roca et al.   CELL

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis

(2008) Damon A. Lowes et al.   FREE RADICAL BIOLOGY AND MEDICINE