Article
Geosciences, Multidisciplinary
S. Navaneetha Krishnan, L. S. Ganesh, C. Rajendran
Summary: This article investigates the behavior of entrepreneurial ventures during the COVID-19 pandemic crisis and proposes entrepreneurial interventions as a crisis management strategy.
INTERNATIONAL JOURNAL OF DISASTER RISK REDUCTION
(2022)
Review
Pharmacology & Pharmacy
Chiara Giacomelli, Rebecca Piccarducci, Laura Marchetti, Chiara Romei, Claudia Martini
Summary: Pulmonary fibrosis (PF) is characterized by chronic inflammation and collagen deposition in the interalveolar space and is a hallmark of interstitial lung diseases (ILDs). Infectious agents have emerged as driving causes for PF development, with SARS-CoV-2 virus being associated with ARDS and PF development. Understanding PF etiology is necessary for developing effective therapeutic strategies, and COVID-19 pathology presents an opportunity for this.
BIOCHEMICAL PHARMACOLOGY
(2021)
Article
Multidisciplinary Sciences
John P. Ansah, David Bruce Matchar, Sean Lam Shao Wei, Jenny G. Low, Ahmad Reza Pourghaderi, Fahad Javaid Siddiqui, Tessa Lui Shi Min, Aloysius Chia Wei-Yan, Marcus Eng Hock Ong
Summary: The study utilized a modified SIR model to examine COVID-19 infection in Singapore, revealing that under containment intervention, the confirmed and actual infection cases were 52,053 and 86,041 respectively, with the actual cases being 1.65 times the confirmed cases.
Article
Health Care Sciences & Services
Maurizio Massaro, Paola Tamburro, Matteo La Torre, Francesca Dal Mas, Ronald Thomas, Lorenzo Cobianchi, Paul Barach
Summary: The COVID-19 pandemic has disrupted traditional communication channels and societal norms globally, particularly evident in Italy where social media discourse around the virus evolved rapidly in response to the crisis. This study explores how themes in online conversations shifted in relation to the implementation of social distancing measures and non-pharmaceutical interventions, emphasizing the importance of credible scientific voices in combating misinformation and fostering public trust during a pandemic.
JOURNAL OF MEDICAL SYSTEMS
(2021)
Article
Public, Environmental & Occupational Health
Nils Chr Stenseth, Guha Dharmarajan, Ruiyun Li, Zheng-Li Shi, Ruifu Yang, George F. Gao
Summary: This article summarizes the timeline of the COVID-19 pandemic and the lessons learned by the public health community, discussing the implications for future public health policy and outlining an agenda for improved pandemic control. It contrasts the ongoing pandemic with the SARS outbreak, identifying areas where valuable lessons were learned as well as key areas where international public health policy failed.
FRONTIERS IN PUBLIC HEALTH
(2021)
Review
Biochemistry & Molecular Biology
Maochen Li, Han Wang, Lili Tian, Zehan Pang, Qingkun Yang, Tianqi Huang, Junfen Fan, Lihua Song, Yigang Tong, Huahao Fan
Summary: This article systematically assesses the safety and efficacy of COVID-19 vaccines, including their potential complications and effects on different populations. It recommends governments and relevant agencies to continue the vaccination process while paying attention to vaccine safety, timely treatment of complications, vaccine development, and ensuring patient well-being. Additional measures like mix-and-match vaccination, developing new types of vaccines, and optimizing immune adjuvants are suggested to improve vaccine safety and effectiveness.
SIGNAL TRANSDUCTION AND TARGETED THERAPY
(2022)
Editorial Material
Immunology
Timothy Sullivan
Summary: Since the emergence of COVID-19 over 3 years ago, more than 1200 articles have been written to document the lessons learned from the pandemic. However, it is not feasible to read all of these articles, leading to the use of machine learning clustering analysis to obtain an overview and emphasize the benefits of using machine learning in analyzing the extensive and constantly expanding COVID-19 literature.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Review
Immunology
Karin Bok, Sandra Sitar, Barney S. Graham, John R. Mascola
Summary: The US government's successful effort in developing COVID-19 vaccines involved integrating expertise and infrastructure from both the public and private sectors, resulting in the rapid advancement of multiple vaccine candidates being administered globally.
Review
Medicine, General & Internal
Alberto Corra, Alice Verdelli, Elena Biancamaria Mariotti, Valentina Ruffo di Calabria, Lavinia Quintarelli, Cristina Aimo, Cord H. Sunderkoetter, Marzia Caproni
Summary: This study aims to collect multiple cases from the literature and analyze the frequency of different forms of induced vasculitis, as well as their histological and immunopathological features. Although rare, CV induced by SARS-CoV-2 and vaccines may provide useful insights into the mechanisms underlying cutaneous and systemic vasculitis.
FRONTIERS IN MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Joseph T. Wu, Kathy Leung, Tommy T. Y. Lam, Michael Y. Ni, Carlos K. H. Wong, J. S. Malik Peiris, Gabriel M. Leung
Summary: Epidemic nowcasting involves assessing the current state of an outbreak by understanding key characteristics, providing situational awareness, and informing control responses. Scientists must constantly update their aims and analytics to incorporate new questions, data, and findings in order to synthesize real-time evidence for policy decisions. Recent advances in computational and laboratory sciences are enhancing the scope, timeliness, reliability, and utility of epidemic nowcasting.
Editorial Material
Biochemical Research Methods
Vivien Marx
Summary: Facing COVID-19, the Global South utilizes networking and creativity to fight against the pandemic.
Article
Multidisciplinary Sciences
Nuria Lopez, Luigi Del Debbio, Marc Baaden, Matej Praprotnik, Laura Grigori, Catarina Simoes, Serge Bogaerts, Florian Berberich, Thomas Lippert, Janne Ignatius, Philippe Lavocat, Oriol Pineda, Maria Grazia Giuffreda, Sergi Girona, Dieter Kranzlmuller, Michael M. Resch, Gabriella Scipione, Thomas Schulthess
Summary: PRACE, an international association, has allocated significant computing resources to fight the COVID-19 pandemic and believes that supercomputing plays an important role in addressing global societal challenges and crisis management.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biotechnology & Applied Microbiology
Annette von Delft, Matthew D. Hall, Ann D. Kwong, Lisa A. Purcell, Kumar Singh Saikatendu, Uli Schmitz, John A. Tallarico, Alpha A. A. Lee
Summary: The COVID-19 pandemic has led to rapid and collaborative efforts in drug discovery. This article summarizes the scientific drivers and considerations behind these antiviral small-molecule discovery programs and proposes strategies to accelerate future efforts.
NATURE REVIEWS DRUG DISCOVERY
(2023)
Article
Multidisciplinary Sciences
Malina A. Bakowski, Nathan Beutler, Karen C. Wolff, Melanie G. Kirkpatrick, Emily Chen, Tu-Trinh H. Nguyen, Laura Riva, Namir Shaabani, Mara Parren, James Ricketts, Anil K. Gupta, Kastin Pan, Peiting Kuo, MacKenzie Fuller, Elijah Garcia, John R. Teijaro, Linlin Yang, Debashis Sahoo, Victor Chi, Edward Huang, Natalia Vargas, Amanda J. Roberts, Soumita Das, Pradipta Ghosh, Ashley K. Woods, Sean B. Joseph, Mitchell V. Hull, Peter G. Schultz, Dennis R. Burton, Arnab K. Chatterjee, Case W. McNamara, Thomas F. Rogers
Summary: The study presents a screening pipeline to discover SARS-CoV-2 inhibitors, identifying 49 compounds in HeLa-ACE2 and 41 in Calu-3 capable of selectively inhibiting virus replication. Antivirals nelfinavir and parent of prodrug MK-4482 show promising activity in vitro and in animal models.
NATURE COMMUNICATIONS
(2021)
Editorial Material
Biochemistry & Molecular Biology
Ines Hassan, Genevie Fernandes, Mitsuru Mukaigawara, Devi Sridhar
Summary: Pandemic preparedness plans should prioritize fair access to diagnostics, vaccines, and therapeutics, and include strategies to build trust and combat disinformation.