Article
Engineering, Multidisciplinary
Weimin Tan, Yinyin Cao, Xiaojing Ma, Ganghui Ru, Jichun Li, Jing Zhang, Yan Gao, Jialun Yang, Guoying Huang, Bo Yan, Jian Li
Summary: Congenital heart disease (CHD) is the leading cause of infant death. An artificial intelligence (AI)-based CHD diagnosis network (CHDNet) is developed to judge whether echocardiogram videos contain heart defects. To overcome the unreliability of AI in cases outside of the training set, Bayesian inference and dynamic neural feedback mechanisms are introduced to improve the diagnostic reliability of AI.
Article
Pediatrics
Indah K. Murni, Muhammad Taufik Wirawan, Linda Patmasari, Esta R. Sativa, Nadya Arafuri, Sasmito Nugroho, Noormanto
Summary: This study found that six out of ten children with CHD were diagnosed with significant delay, with delayed diagnosis by doctor being the most common cause. Children with cyanotic CHD who lived outside the city, had non-syndromic conditions, low family income, normal labor, and term gestation at birth were more likely to experience delayed diagnosis. Comorbid complications like heart failure and pulmonary hypertension were prevalent in children with delayed diagnosis of CHD.
Article
Chemistry, Analytical
Kiichi Takahashi, Kyoichi Ono, Hirokazu Arai, Hiroyuki Adachi, Masato Ito, Akie Kato, Tsutomu Takahashi
Summary: This study evaluated the capability of a piezoelectric sensor to detect heart murmurs in neonates with congenital heart defects. The results showed that the amplitudes of systolic murmurs detected by the piezoelectric sensor were significantly higher in neonates with congenital heart defects compared to healthy neonates, with a strong correlation between recordings from the piezoelectric sensor and electronic stethoscope. The piezoelectric sensor was found to objectively detect heart murmurs, and future improvements in mechanical design and automatic analysis algorithms are expected to enhance recording quality.
Article
Cardiac & Cardiovascular Systems
Richard D. Mainwaring, L. Mac Felmly, R. Thomas Collins, Frank L. Hanley
Summary: This study retrospectively reviewed 69 patients with Alagille syndrome who underwent congenital heart surgery and found that liver dysfunction had a significant impact on their surgical survival.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2022)
Article
Public, Environmental & Occupational Health
Marie Tindborg, Anders Koch, Mikael Andersson, Klaus Juul, Uka Wilhjelm Geisler, Bolette Soborg, Sascha Wilk Michelsen
Summary: The incidence rates of heart disease (HD) and congenital heart disease (CHD) were compared between young Inuit populations in Greenland and Denmark. It was found that the incidence rate of HD was lower in Greenland compared to Denmark, while the incidence rates of CHD were similar in both countries. Individuals of Inuit/mixed ethnicity had a higher risk of both HD and CHD compared to non-Inuit individuals in both countries.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Review
Health Care Sciences & Services
Olga Maria Diz, Rocio Toro, Sergi Cesar, Olga Gomez, Georgia Sarquella-Brugada, Oscar Campuzano
Summary: Congenital heart disease is a group of pathologies characterized by structural malformations of the heart or great vessels, with genetic variants playing a key role. High-throughput genetic technologies can help identify pathogenic factors. Early diagnosis and personalized treatment are crucial due to the high incidence and associated complications.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Multidisciplinary Sciences
Xin Li, Jin Zhu, Jun An, Yuqing Wang, Yili Wu, Xuezhi Li
Summary: This study investigated the growth retardation status of Chinese pediatric TOF patients under 5 years old and found that their body height, weight, and BMI were significantly lower than WHO Child Growth Standards. The study also revealed that older TOF patients (aged 13-60 months) experienced more stunting and deterioration in body height and weight compared to infants (aged 0-12 months), highlighting the importance of early intervention to prevent severe growth retardation.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Forod Salehi, Kimia Darmiani, Sameneh Nakhaee, Alireza Amirabadi Zadeh, Seyed Yoosef Javadmoosavi, Vahideh Faghihi, Omid Mehrpour
Summary: This study found that mothers of children with congenital heart disease had significantly higher blood lead concentrations compared to mothers of healthy children.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2022)
Article
Cardiac & Cardiovascular Systems
Son Q. Duong, Mahmud O. Elfituri, Isabella Zaniletti, Robert W. Ressler, Clemens Noelke, Bruce D. Gelb, Robert H. Pass, Carol R. Horowitz, Howard S. Seiden, Brett R. Anderson
Summary: Racial and ethnic factors contribute to disparities in pediatric congenital heart disease surgery outcomes. Childhood opportunity index is associated with race, ethnicity, and in-hospital surgical death rates.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Alina Weissmann-Brenner, Noam Domniz, Raanan Meyer, Tal Weissbach, Tal Elkan, Yishai Salem, Yossi Bart, Eran Kassif, Boaz Weisz
Summary: The study examines the impact of prenatal diagnosis on delivery outcomes of neonates with congenital heart defects (CHD). Findings suggest that pregnancies with CHD have higher rates of diabetes, chronic hypertension, inductions of labor, and cesarean deliveries compared to control pregnancies. Prenatal diagnosis of CHD is associated with increased induction of labor, but does not affect the mode of delivery. Neonates with CHD have lower birthweight and higher incidence of hypoxic ischemic encephalopathy and seizures compared to controls, regardless of prenatal diagnosis. The 5-min Apgar score is lower in pregnancies with postnatal diagnosis of CHD.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Giulia Poretti, Stiljan Hoxha, Antonio Segreto, Gardellini Jacopo, Camilla Sandrini, Giuseppe Faggian, Alessandro Varrica, Massimo Chessa, Alessandro Giamberti, Giovanni Battista Luciani
Summary: Cryoablation for supraventricular arrhythmias in ACHD patients is a safe and effective procedure with a low risk of recurrence, and surgical treatment should be considered when further open-heart repair is needed.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Microbiology
Maria Hofmann, Nelly Schulz-Weidner, Norbert Kraemer, Torsten Hain
Summary: Children with congenital heart disease have poorer oral health compared with healthy children, possibly due to differences in oral bacterial colonization.
Article
Pediatrics
Rachel K. Hopper, Steven H. Abman, Eleni G. Elia, Catherine M. Avitabile, Delphine Yung, Mary P. Mullen, Eric D. Austin, Angela Bates, Stephanie S. Handler, Jeffrey A. Feinstein, D. Dunbar Ivy, John P. Kinsella, Kenneth D. Mandl, J. Usha Raj, Lynn A. Sleeper
Summary: This study characterized comorbidities, outcomes, and treatment patterns in children with Down syndrome and pulmonary hypertension. The results showed that despite the presence of cardiac and respiratory comorbidities, children with Down syndrome-associated pulmonary hypertension have a similar survival rate to those with non-Down syndrome-associated pulmonary hypertension.
JOURNAL OF PEDIATRICS
(2023)
Article
Cardiac & Cardiovascular Systems
Jia Liu, Haolin Wang, Zhen Yang, Junjun Quan, Lingjuan Liu, Jie Tian
Summary: The study aimed to explore a new algorithm model that leverages deep learning for screening and diagnosing left-to-right shunt congenital heart disease (CHD) in children. With deep learning, screening models were constructed, successfully identifying 884 heart sound recordings from children with this type of CHD. The RCRnet model showed higher accuracy in diagnosing various types of CHD compared to expert auscultation. Additionally, there were weak correlations between heart sounds and LVEF, RVSP, and malformation size.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Review
Health Care Sciences & Services
Sophia Livas de Morais Almeida, Luisa Tiemi Souza Tuda, Marcela Bezerra Dias, Luana Izabela Azevedo de Carvalho, Thayla Lais Lima Estevam, Ana Luiza Menezes Teles Novelleto, Edward Araujo Junior, Luciane Alves da Rocha Amorim
Summary: This study aims to identify and summarize the literature on family counseling in cases of CHD diagnosis during pregnancy, revealing the difficulties, opportunities, and challenges in effectively conducting family counseling. Most of the included studies were cross-sectional and qualitative, and all were from developed countries.
Article
Engineering, Biomedical
Zhaoming He, Kailiang Zhang, Teng Jing, Yong Wang
ANNALS OF BIOMEDICAL ENGINEERING
(2017)
Article
Cardiac & Cardiovascular Systems
Avik Basu, Carla Lacerda, Zhaoming He
CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
(2018)
Article
Cardiac & Cardiovascular Systems
Hao Wang, Zhan Cui, Zhongxi Zhou, Zhaoming He
Summary: The study aimed to develop a novel single opening&closing pulsatile flow in-vitro valve tester for direct measurement of closing volume of the heart valve. The tester successfully simulates and evaluates the opening and closing hemodynamics of the heart valve and accurately measures valve closing volume and time.
CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
(2022)
Article
Mechanics
Yang Yang, Xionghuan Chen, Ling Bai, Yulong Yao, Hui Wang, Leilei Ji, Zhaoming He, Xiangyu Song, Ling Zhou
Summary: Pressure fluctuation is a significant factor affecting the stability of rotating machinery, especially in the case of multistage electric submersible pumps (ESPs). In this study, we introduce a parameter called energy flow density (EFD) to directly quantify the intensity of pressure fluctuations. Through theoretical analysis, numerical simulation, and test verification, we investigate the characteristics and inter-stage interference of pressure fluctuations in a typical three-stage ESP. We compare the results obtained from the EFD method with the conventional method and find that the EFD method accurately characterizes the multistage ESP pressure fluctuation and reflects subtle differences due to inter-stage propagation and coupling.
