3-Arylidene-N-hydroxyoxindoles: A New Class of Compounds Endowed with Antitumor Activity

Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors

(2015) Loana Musso et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

N′-Alkylaminosulfonyl Analogues of 6-Fluorobenzylideneindolinones with Desirable Physicochemical Profiles and Potent Growth Inhibitory Activities on Hepatocellular Carcinoma

(2015) Xiao Chen et al.   ChemMedChem

Photoinduced Isomerization and Hepatoxicities of Semaxanib, Sunitinib and Related 3-Substituted Indolin-2-ones

(2015) Mun Hong Ngai et al.   ChemMedChem

Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands for α-Synuclein Fibrils

(2015) Wenhua Chu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small molecule compounds targeting the p53 pathway: are we finally making progress?

(2014) Xin Yu et al.   APOPTOSIS

Bioisosteric replacement of an acylureido moiety attached to an indolin-2-one scaffold with a malonamido or a 2/4-pyridinoylamido moiety produces a selectively potent Aurora-B inhibitor

(2014) Hsiao-Chun Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and in vitro and in vivo antitumour activity of 3-benzylideneindolin-2-one derivatives, a novel class of small-molecule inhibitors of the MDM2–p53 interaction

(2014) Guang-hui Zheng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design of the influenza virus inhibitors targeting the PA endonuclease using 3D-QSAR modeling, side-chain hopping, and docking

(2013) Zhihui Yan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Discovery of PLK4 Inhibitors: (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-ones as Novel Antiproliferative Agents

(2013) Radoslaw Laufer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Biological and Computational Evaluation of Novel Oxindole Derivatives as Inhibitors of Src Family Kinases

(2013) Zühal Kilic-Kurt et al.   Letters in Drug Design & Discovery

Tripolin A, a Novel Small-Molecule Inhibitor of Aurora A Kinase, Reveals New Regulation of HURP's Distribution on Microtubules

(2013) Iliana A. Kesisova et al.   PLoS One

Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators

(2013) Li-Fang Yu et al.   ACS Medicinal Chemistry Letters

Synthesis and structure–activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors

(2010) Rahul R. Khanwelkar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

3-Alkenyl-oxindoles: Natural Products, Pharmaceuticals, and Recent Synthetic Advances in Tandem/Telescoped Approaches

(2010) Alessia Millemaggi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Design, synthesis, and evaluation of biphenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors

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