Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer

REC8 inhibits EMT by downregulating EGR1 in gastric cancer cells

(2018) Junhong Zhao et al.   ONCOLOGY REPORTS

Isoform-selective activity-based profiling of ERK signaling

(2018) Myungsun Shin et al.   Chemical Science

Identification of Biological Targets of Therapeutic Intervention for Hepatocellular Carcinoma by Integrated Bioinformatical Analysis

(2018) Wei Qi Hu et al.   MEDICAL SCIENCE MONITOR

A novel EGR-1 dependent mechanism for YB-1 modulation of paclitaxel response in a triple negative breast cancer cell line

(2016) Annette Lasham et al.   INTERNATIONAL JOURNAL OF CANCER

A Positive Feed-forward Loop Associating EGR1 and PDGFA Promotes Proliferation and Self-renewal in Glioblastoma Stem Cells

(2016) Nathalie Sakakini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RAS isoforms and mutations in cancer at a glance

(2016) G. Aaron Hobbs et al.   JOURNAL OF CELL SCIENCE

ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron Survival

(2015) D. E. O'Brien et al.   JOURNAL OF NEUROSCIENCE

MEK Inhibitor Selumetinib (AZD6244; ARRY-142886) Prevents Lung Metastasis in a Triple-Negative Breast Cancer Xenograft Model

(2015) C. Bartholomeusz et al.   MOLECULAR CANCER THERAPEUTICS

Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis

(2014) R Cao et al.   BRITISH JOURNAL OF CANCER

The MAPK pathway across different malignancies: A new perspective

(2014) Mauricio Burotto et al.   CANCER

Quantification of a Pharmacodynamic ERK End Point in Melanoma Cell Lysates: Toward Personalized Precision Medicine

(2014) Mangalika Warthaka et al.   ACS Medicinal Chemistry Letters

EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression

(2014) Huihua Zhang et al.   Scientific Reports

Egr-1 enhances drug resistance of breast cancer by modulating MDR1 expression in a GGPPS-independent manner

(2013) Weiwei Tao et al.   BIOMEDICINE & PHARMACOTHERAPY

ERK-ERF-EGR1, a novel switch underlying acquisition of a motile phenotype

(2013) Nir Ben-Chetrit et al.   Cell Adhesion & Migration

Ras/ERK1 pathway regulation of p27KIP1-mediated G1-phase cell-cycle arrest in cordycepin-induced inhibition of the proliferation of vascular smooth muscle cells

(2012) Su-Mi Jung et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapy

(2012) Libero Santarpia et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

High ERK Protein Expression Levels Correlate with Shorter Survival in Triple-Negative Breast Cancer Patients

(2012) C. Bartholomeusz et al.   ONCOLOGIST

Early growth response 1 regulates glucose deprivation-induced necrosis

(2012) HYUN MIN JEON et al.   ONCOLOGY REPORTS

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF

(2011) Gabi Tarcic et al.   FASEB JOURNAL

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Triple-Negative Breast Cancer: An Unmet Medical Need

(2011) C. A. Hudis et al.   ONCOLOGIST

ERK2 but Not ERK1 Induces Epithelial-to-Mesenchymal Transformation via DEF Motif-Dependent Signaling Events

(2010) Sejeong Shin et al.   MOLECULAR CELL

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL