Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps

Cryo-EM structures of Helicobacter pylori vacuolating cytotoxin A oligomeric assemblies at near-atomic resolution

(2019) Kaiming Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atomic Resolution Cryo-EM Structure of β-Galactosidase

(2018) Alberto Bartesaghi et al.   STRUCTURE

De novo main-chain modeling for EM maps using MAINMAST

(2018) Genki Terashi et al.   Nature Communications

Automated map sharpening by maximization of detail and connectivity

(2018) Thomas C. Terwilliger et al.   Acta Crystallographica Section D-Structural Biology

Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome

(2018) Yuanchen Dong et al.   NATURE

A fully automatic method yielding initial models from high-resolution cryo-electron microscopy maps

(2018) Thomas C. Terwilliger et al.   NATURE METHODS

Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating

(2018) Ling Zhu et al.   Nature Communications

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

(2016) Alan Merk et al.   CELL

Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel

(2016) Xiao Tao et al.   NATURE

A Stochastic Point Cloud Sampling Method for Multi-Template Protein Comparative Modeling

(2016) Jilong Li et al.   Scientific Reports

Protein single-model quality assessment by feature-based probability density functions

(2016) Renzhi Cao et al.   Scientific Reports

Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity

(2015) Eva Nogales et al.   MOLECULAR CELL

Cryo-electron microscopy structure of the Slo2.2 Na+-activated K+ channel

(2015) Richard K. Hite et al.   NATURE

Deep learning

(2015) Yann LeCun et al.   NATURE

De novo protein structure determination from near-atomic-resolution cryo-EM maps

(2015) Ray Yu-Ruei Wang et al.   NATURE METHODS

How cryo-EM is revolutionizing structural biology

(2015) Xiao-chen Bai et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution

(2014) Zhen Yan et al.   NATURE

Tracing Beta Strands Using StrandTwister from Cryo-EM Density Maps at Medium Resolutions

(2014) Dong Si et al.   STRUCTURE

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

(2013) Maofu Liao et al.   NATURE

High-Resolution Comparative Modeling with RosettaCM

(2013) Yifan Song et al.   STRUCTURE

A Machine Learning Approach for the Identification of Protein Secondary Structure Elements from Electron Cryo-Microscopy Density Maps

(2012) Dong Si et al.   BIOPOLYMERS

Rapid chain tracing of polypeptide backbones in electron-density maps

(2010) Thomas C. Terwilliger   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Rapid model building of α-helices in electron-density maps

(2010) Thomas C. Terwilliger   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Improved prediction of protein side-chain conformations with SCWRL4

(2009) Georgii G. Krivov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Fast procedure for reconstruction of full-atom protein models from reduced representations

(2008) Piotr Rotkiewicz et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY