Voltage-Dependent Protonation of the Calcium Pocket Enable Activation of the Calcium-Activated Chloride Channel Anoctamin-1 (TMEM16A)
出版年份 2020 全文链接
标题
Voltage-Dependent Protonation of the Calcium Pocket Enable Activation of the Calcium-Activated Chloride Channel Anoctamin-1 (TMEM16A)
作者
关键词
-
出版物
Scientific Reports
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-04-20
DOI
10.1038/s41598-020-62860-9
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ca2+-activated Cl− channel TMEM16A/ANO1 identified in zebrafish skeletal muscle is crucial for action potential acceleration
- (2019) Anamika Dayal et al. Nature Communications
- PKAD: a database of experimentally measured pKa values of ionizable groups in proteins
- (2019) Swagata Pahari et al. Database-The Journal of Biological Databases and Curation
- Phosphatidylinositol 4,5-bisphosphate (PIP2) and Ca2+ are both required to open the Cl- channel TMEM16A
- (2019) Maiwase Tembo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The multifaceted role of TMEM16A in cancer
- (2019) David Crottès et al. CELL CALCIUM
- TMEM16A expression in cholinergic neurons of the medial habenula mediates anxiety‐related behaviors
- (2019) Chang‐Hoon Cho et al. EMBO REPORTS
- Wasted TMEM16A channels are rescued by phosphatidylinositol 4,5-bisphosphate
- (2019) Jorge Arreola et al. CELL CALCIUM
- Phosphatidylinositol 4,5-bisphosphate, cholesterol, and fatty acids modulate the calcium-activated chloride channel TMEM16A (ANO1)
- (2018) José J. De Jesús-Pérez et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- TMEM16A inhibition impedes capacitation and acquisition of hyperactivated motility in guinea pig sperm
- (2018) Joaquín Cordero-Martínez et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The TMEM16A channel mediates the fast polyspermy block inXenopus laevis
- (2018) Katherine L. Wozniak et al. JOURNAL OF GENERAL PHYSIOLOGY
- The Sixth Transmembrane Segment Is a Major Gating Component of the TMEM16A Calcium-Activated Chloride Channel
- (2018) Christian J. Peters et al. NEURON
- Systems analysis of intracellular pH vulnerabilities for cancer therapy
- (2018) Erez Persi et al. Nature Communications
- Calcium-dependent electrostatic control of anion access to the pore of the calcium-activated chloride channel TMEM16A
- (2018) Andy KM Lam et al. eLife
- Extracellular protons enable activation of the calcium-dependent chloride channel TMEM16A
- (2017) Silvia Cruz-Rangel et al. JOURNAL OF PHYSIOLOGY-LONDON
- Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM
- (2017) Cristina Paulino et al. NATURE
- Cytoplasmic Cl−couples membrane remodeling to epithelial morphogenesis
- (2017) Mu He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker
- (2016) Chau M Ta et al. BRITISH JOURNAL OF PHARMACOLOGY
- The Ca2+-activated Cl−channel TMEM16B regulates action potential firing and axonal targeting in olfactory sensory neurons
- (2016) Gianluca Pietra et al. JOURNAL OF GENERAL PHYSIOLOGY
- Protons inhibit anoctamin 1 by competing with calcium
- (2015) Hyeyeon Chun et al. CELL CALCIUM
- Gating modes of calcium-activated chloride channels TMEM16A and TMEM16B
- (2015) Silvia Cruz-Rangel et al. JOURNAL OF PHYSIOLOGY-LONDON
- Anoctamin 1 (Ano1) is required for glucose-induced membrane potential oscillations and insulin secretion by murine β-cells
- (2015) Raphaël Crutzen et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Disruption of vascular Ca2+-activated chloride currents lowers blood pressure
- (2014) Christoph Heinze et al. JOURNAL OF CLINICAL INVESTIGATION
- The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function
- (2014) Diana Faria et al. KIDNEY INTERNATIONAL
- Structure and Function of TMEM16 Proteins (Anoctamins)
- (2014) Nicoletta Pedemonte et al. PHYSIOLOGICAL REVIEWS
- Correction: PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors
- (2014) Yang Ni et al. PLoS One
- A comprehensive search for calcium binding sites critical for TMEM16A calcium-activated chloride channel activity
- (2014) Jason Tien et al. eLife
- The Ca2+-activated Cl−channel, ANO1 (TMEM16A), is a double-edged sword in cell proliferation and tumorigenesis
- (2014) Zhiqiang Qu et al. Cancer Medicine
- Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling
- (2013) Adrian Britschgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
- (2012) U. Duvvuri et al. CANCER RESEARCH
- Explaining Calcium-Dependent Gating of Anoctamin-1 Chloride Channels Requires a Revised Topology
- (2012) Kuai Yu et al. CIRCULATION RESEARCH
- The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons
- (2012) Hawon Cho et al. NATURE NEUROSCIENCE
- Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction
- (2012) F. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop
- (2011) Q. Xiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Ca2+-activated Cl− channels by gallotannins as a possible molecular basis for health benefits of red wine and green tea
- (2010) Wan Namkung et al. FASEB JOURNAL
- Tmem16AEncodes the Ca2+-activated Cl−Channel in Mouse Submandibular Salivary Gland Acinar Cells
- (2010) Victor G. Romanenko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
- (2010) Johanna Chiche et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Control of volume-sensitive chloride channel inactivation by the coupled action of intracellular chloride and extracellular protons
- (2010) Carmen Y. Hernández-Carballo et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Phenomics of cardiac chloride channels: the systematic study of chloride channel function in the heart
- (2009) Dayue Duan JOURNAL OF PHYSIOLOGY-LONDON
- Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles
- (2009) Sung Jin Hwang et al. JOURNAL OF PHYSIOLOGY-LONDON
- Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit
- (2008) Björn Christian Schroeder et al. CELL
- TMEM16A confers receptor-activated calcium-dependent chloride conductance
- (2008) Young Duk Yang et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started