Review
Food Science & Technology
Yaping Zhou, Zhongxing Chu, Yi Luo, Feiyan Yang, Fuliang Cao, Feijun Luo, Qinlu Lin
Summary: Due to the fast-paced lifestyle, many people suffer from unexplained fatigue, which can have a serious impact on their health and daily functioning. Dietary polysaccharides have been found to have specific anti-fatigue effects and can be activated during food processing or gastrointestinal transit. This review aims to summarize the latest advances in understanding the biological processes of exercise-induced fatigue and the potential molecular mechanisms of dietary polysaccharides in alleviating fatigue.
Review
Medicine, General & Internal
Jiaxi Zhao, Yiqin Huang, Xiaofeng Yu
Summary: This review highlights the relationship between gut microbiota and muscle mass/function, indicating the establishment of the gut-muscle axis and its impact on sarcopenia. The gut microbiota can influence muscle health through various pathways such as inflammation, metabolism, and hormone sensitivity.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Biology
Zhao-Bo Luo, Shengzhong Han, Xi-Jun Yin, Hongye Liu, Junxia Wang, Meifu Xuan, Chunyun Hao, Danqi Wang, Yize Liu, Shuangyan Chang, Dongxu Li, Kai Gao, Huiling Li, Biaohu Quan, Lin-Hu Quan, Jin-Dan Kang
Summary: The host genome and intestinal microbiota have mutual influences on each other. Deletion of the myostatin (MSTN) gene in pigs positively regulates the expression of tight junction-related genes in the intestine, leading to changes in the structure of the intestinal microbiota. Transplantation of the intestinal microbiota from MSTN-deficient pigs into mice resulted in increased muscle growth and higher levels of short-chain fatty acids.
Article
Pharmacology & Pharmacy
Tianyang Xu, Dong Yang, Kaiyuan Liu, Qiuming Gao, Zhongchen Liu, Guodong Li
Summary: This study demonstrated that MY alleviated OA symptoms by increasing the abundance of certain microbes and modulating metabolites, restoring succinate dehydrogenase and muscle glycogen levels, reversing the expression of relevant genes and proteins induced by OA, and promoting joint damage repair and protection against OA via the gut-muscle-joint axis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Microbiology
Caijun Zhao, Xiaoyu Hu, Min Qiu, Lijuan Bao, Keyi Wu, Xiangyue Meng, Yihong Zhao, Lianjun Feng, Shiyu Duan, Yuhong He, Naisheng Zhang, Yunhe Fu
Summary: This study demonstrates that gut microbiota disturbance caused by metabolic abnormalities of gut microbiota is associated with the occurrence and development of mastitis. The underlying mechanism of how gut dysbiosis leads to mastitis pathogenesis remains unclear. Additionally, the regulation of commensal bacteria and gut metabolism may provide a potential strategy for mastitis intervention.
Review
Nutrition & Dietetics
Giuseppe Marano, Marianna Mazza, Francesco Maria Lisci, Michele Ciliberto, Gianandrea Traversi, Georgios Demetrios Kotzalidis, Domenico De Berardis, Lucrezia Laterza, Gabriele Sani, Antonio Gasbarrini, Eleonora Gaetani
Summary: There is increasing interest in the role of intestinal microbiota and autoimmune processes in psychiatric diseases. Altered communication between the microbiota-gut-brain axis may be a cause of psychiatric disorders. This review explores the evidence for the involvement of gut microbiota in psychiatric diseases and the impact of diet on microbiota and mental health. Changes in gut microbiota composition can lead to increased intestinal permeability, resulting in a cytokine storm, systemic inflammation, and immune response. These events can affect neurotransmitter release, alter the hypothalamic-pituitary-adrenal axis, and reduce trophic brain factors. Further research is needed to understand the underlying mechanisms connecting gut microbiota and psychiatric disorders.
Review
Immunology
Haoran Wang, Tingting Zhao, Zhenjiang Liu, Danzengquzhen, Cisangzhuoma, Jinying Ma, Xin Li, Xiaodan Huang, Bin Li
Summary: Recent investigations suggest that dietary consumption of flavonoids has neuroprotective effects by inhibiting neuroinflammatory and oxidative stress responses. Flavonoids may also shape gut microbiota composition and promote the growth of beneficial bacteria that produce neuroprotective metabolites. By influencing the microbiota-gut-brain axis, flavonoids indirectly improve brain health.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Editorial Material
Microbiology
Melanie G. Gareau
Summary: The gut microbiota plays a significant role in the development and severity of various diseases, including those affecting the central nervous system. The microbiota-gut-brain axis enables communication between gut microbes and the brain to regulate behavior. This commentary highlights recent findings on the role of gut microbiota and bacterial metabolites in sepsis-associated encephalopathy using a mouse model.
Article
Engineering, Environmental
Peng Zhang, Liyang Zheng, Yitao Duan, Yuting Gao, Huihui Gao, Daqing Mao, Yi Luo
Summary: The study revealed that TCS can cause liver injury by disturbing lipid metabolism and dysbiosis of gut microbiota. TCS also increases intestinal permeability, contributing to liver damage. The research provides new insights into the health impact of TCS on the human body.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Review
Biochemistry & Molecular Biology
Thomas M. Barber, Georgios Valsamakis, George Mastorakos, Petra Hanson, Ioannis Kyrou, Harpal S. Randeva, Martin O. Weickert
Summary: Our gut microbiota have co-evolved with us over a long period of time, playing a crucial role in our overall health and influencing various bodily processes. The microbiota-gut-brain axis is a dominant communication pathway with far-reaching implications for our well-being. Dietary composition, particularly in modern Western diets, can directly impact the abundance and diversity of gut microbiota, leading to dysbiosis and potential health issues.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Federico Fontana, Giulia Longhi, Chiara Tarracchini, Leonardo Mancabelli, Gabriele Andrea Lugli, Giulia Alessandri, Francesca Turroni, Christian Milani, Marco Ventura
Summary: The correlation between the physical performance of athletes and their gut microbiota has been studied, and it has been found that the gut microbiota plays a crucial role in the health status of athletes. The metabolic activity of the microbial population in the large intestine of athletes may influence their physical performance.
Review
Biochemistry & Molecular Biology
Angel Yun-Kuan Thye, Yi-Rou Bah, Jodi Woan-Fei Law, Loh Teng-Hern Tan, Ya-Wen He, Sunny-Hei Wong, Sivakumar Thurairajasingam, Kok-Gan Chan, Learn-Han Lee, Vengadesh Letchumanan
Summary: Evidence suggests that the gut microbiome plays a role in modulating the development of diseases beyond the gastrointestinal tract, including skin disorders. The gut-skin axis refers to the bidirectional relationship between the gut microbiome and skin health, regulated through mechanisms such as inflammatory mediators and the immune system. Microbiota dysregulation has been observed in various inflammatory skin conditions, such as atopic dermatitis, rosacea, and psoriasis. Understanding the involvement of the gut microbiome in regulating skin health could lead to the development of novel therapies for these skin disorders, particularly psoriasis.
Review
Neurosciences
Mahmoud Salami, Masoud Soheili
Summary: It is well known that the gut microbiota influences the development and function of the nervous system, particularly through the bidirectional communication with the hippocampus. A healthy gut microbiota is crucial for normal hippocampus-dependent learning and memory, as well as synaptic plasticity.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Microbiology
Lidong Zhang, Hedong Lang, Li Ran, Guoliang Tian, Hui Shen, Jundong Zhu, Qianyong Zhang, Long Yi, Mantian Mi
Summary: Exercise has been found to have a positive impact on skeletal muscle performance, possibly through its effects on gene expression, grip strength, serum testosterone levels, and muscle cross-sectional area. Furthermore, exercise can alter the structure of the gut microbiota, which may be related to testosterone production.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Environmental Sciences
Jianzhao Liao, Yingwei Liu, Jiangnan Yi, Yuanliang Li, Quanwei Li, Yangwei Li, Peng Shang, Jianying Guo, Lianmei Hu, Jiaqiang Pan, Ying Li, Yung-Fu Chang, Zhaoxin Tang, Hui Zhang
Summary: Batteries are significant contributors to electronic waste and are considered highly ecotoxic pollutants. Exposure to battery waste disrupts intestinal flora and aggravates hepatotoxicity through the gut-liver axis.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Infectious Diseases
Bogusz Jan Aksak-Was, Justyna D. Kowalska, Piotr Zabek, Karol Serwin, Milena Rafalska-Kosior, Joanna Golab, Daniel Chober, Karolina Skonieczna-Zydecka, Malgorzata Hackiewicz, Milosz Parczewski
Summary: The use of antiretroviral treatment has reduced the life expectancy gap between people living with HIV (PLWH) and the general population. Immune restoration is a powerful factor in improving the survival of PLWH, regardless of the speed of recovery.
Article
Nutrition & Dietetics
Beata Loniewska, Magda Fraszczyk-Tousty, Piotr Tousty, Karolina Skonieczna-Zydecka, Dominika Maciejewska-Markiewicz, Igor Loniewski
Summary: This study analyzed 456 fecal samples from 86 children to investigate the influence of perinatal factors on the concentrations of fecal short-chain fatty acids (SCFAs) during the first two years of life. The results showed that SCFA concentrations increased until 12 months and then stabilized. Factors such as antibiotic treatment during pregnancy, mode of delivery, feeding formula, and maternal weight gain were found to be associated with changes in SCFA concentrations. Higher SCFA levels were observed in infants born to mothers with normal pre-pregnancy weight and adequate weight gain. Additionally, female infants had higher levels of acetic acid at 2 years old. The study suggests the need for further long-term epidemiological studies in this area.
Article
Chemistry, Multidisciplinary
Katarzyna Janda-Milczarek, Kinga Szymczykowska, Karolina Jakubczyk, Patrycja Kupnicka, Karolina Skonieczna-Zydecka, Bogumila Pilarczyk, Agnieszka Tomza-Marciniak, Alicja Ligenza, Ewa Stachowska, Bartosz Dalewski
Summary: The study aimed to explore the effect of supplement form (tablet and powder) and cultivation method (organic and conventional) on the mineral content of spirulina supplements. The findings showed that both supplement form and cultivation method had an impact on the mineral content, with powder supplements containing higher amounts of important elements and organic spirulina supplements being a richer dietary source of iron and potassium.
APPLIED SCIENCES-BASEL
(2023)
Article
Pediatrics
Slawomir Zacha, Agata Andrzejewska, Barbara Jastrzebska-Ligocka, Aleksander Szwed, Elzbieta Modrzejewska, Wojciech Zacha, Karolina Skonieczna-Zydecka, Jakub Miegon, Konrad Jarosz, Jowita Biernawska
Summary: This study evaluated the effectiveness of intraoperative intercostal nerve cryolysis in terms of pain management and found that it is more effective than multimodal analgesia in reducing the use of opioids, hospitalization time, and improving postoperative rehabilitation and quality of life. The use of the BackOnFeet application also had a positive effect on patient's quality of life after surgery.
FRONTIERS IN PEDIATRICS
(2023)
Article
Nutrition & Dietetics
Igor Loniewski, Monika Szulinska, Mariusz Kaczmarczyk, Konrad Podsiadlo, Daniel Styburski, Karolina Skonieczna-Zydecka, Pawel Bogdanski
Summary: This study aimed to assess the effects of a multi-strain probiotic formula on fecal short-chain fatty acids (SCFAs). The results showed that the probiotic dose was positively correlated with SCFA content in the stool, and this may lead to a reduction in cardiovascular risk factors by decreasing blood uric acid levels.
Review
Nutrition & Dietetics
Magdalena Sylwia Kaminska, Kamila Rachubinska, Szymon Grochans, Karolina Skonieczna-Zydecka, Anna Maria Cybulska, Elzbieta Grochans, Beata Karakiewicz
Summary: We conducted a systematic literature review and meta-analysis to investigate the role of whey protein supplementation in the functioning of the elderly with sarcopenia. Results demonstrated that whey protein supplementation combined with age-appropriate physical exercise might improve muscle mass and lower limb function in sarcopenic patients. However, study duration and age significantly affect the handgrip strength rate and the chair and stand test rate, respectively, indicating the need to consider these factors for sarcopenia prevention in the high-risk group.
Review
Microbiology
Agata Misera, Igor Loniewski, Joanna Palma, Monika Kulaszynska, Wiktoria Czarnecka, Mariusz Kaczmarczyk, Pawel Liskiewicz, Jerzy Samochowiec, Karolina Skonieczna-Zydecka
Summary: The relationship between drugs and microbiota is two-way. The proper composition and function of microbiota are key factors for some medications used in modern medicine. On the other hand, pharmacotherapeutic agents can significantly modify the microbiota, which in turn affects its function. A recent study revealed that nearly 25% of drugs administered to humans have antimicrobial effects. Multiple antidepressants have antimicrobial properties, and there are antibiotics with proven antidepressant effects. Additionally, antibiotics can cause mental phenotype changes, and some antibiotics have adverse effects including neurological and psychological symptoms, supporting the hypothesis that intestinal microbiota may affect the function of the central nervous system. We have comprehensively collected data on psychiatric drugs and their antimicrobial properties, which we believe has strong implications for the treatment of psychiatric entities. However, our study also highlights the need for more well-designed trials to analyze the function of gut microbiota.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Medicine, General & Internal
Maria Markowicz, Wojciech Skrobot, Agnieszka Labuc, Paulina Poszytek, Agnieszka Orlikowska, Ewelina Perzanowska, Katarzyna Krasowska, Konrad Drewek, Jan J. Kaczor
Summary: This study aimed to determine the impact of exercises activating the intrinsic foot muscles on postural control in children with flat feet, with normal and excessive body weight. After a 6-week rehabilitation program, it was found that the foot position and balance control improved significantly.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Psychiatry
Jerzy Samochowiec, Dorota Frydecka, Karolina Skonieczna-Zydecka, Meryam Schouler-Ocak, Bernardo Carpinello, Eka Chkonia, Geert Dom, Peter Falkai, Blazej Misiak, Mariana Pinto da Costa, Jan Wise, Livia de Picker, Simavi Vahip, Danuta Wasserman, Silvana Galderisi, Przemyslaw Bienkowski
Summary: This study investigates the current status of ethical codes and practices in countries belonging to the European Psychiatric Association (EPA). Most countries rely on mission statements and internal documents to address ethical issues in psychiatry, including medical malpractice, workplace bullying, plagiarism, academic fraud, sexual abuse, and discrimination/racism. NPAs play an active role in defining ethical standards for mental health care professionals, and future collaboration under the EPA's umbrella could establish a database of local ethical documents translated into English for all EPA members.
EUROPEAN PSYCHIATRY
(2023)
Article
Nutrition & Dietetics
Maciej Halasa, Karolina Skonieczna-Zydecka, Boguslaw Machalinski, Leonard Buhner, Magdalena Baskiewicz-Halasa
Summary: This study is the first randomized controlled trial evaluating the preventive effect of bovine colostrum on upper respiratory tract infections in healthy pre-school children. The results showed that bovine colostrum can significantly reduce the incidence and severity of upper respiratory tract infections, and it is safe and well tolerated.
Article
Nutrition & Dietetics
Zofia Kinga Bytowska, Daria Korewo-Labelle, Konrad Kowalski, Witold Libionka, Katarzyna Przewlocka, Wojciech Kloc, Jan Jacek Kaczor
Summary: This study aimed to investigate the effects of BMI-based vitamin D3 administration on the kynurenine pathway and inflammatory state in Parkinson's disease (PD) patients with deep brain stimulation (DBS). The results showed that TNF-a decreased after vitamin D3 administration and there were changes in KP substances. Additionally, a negative correlation between 3-HK and vitamin D metabolites was observed. These findings suggest the neuroprotective abilities of vitamin D3 in PD patients with DBS.
Article
Food Science & Technology
Katarzyna Sielatycka, Joanna Sliwa-Dominiak, Martyna Radaczynska, Wojciech Juzwa, Mariusz Kaczmarczyk, Wojciech Marlicz, Karolina Skonieczna-Zydecka, Igor Loniewski
Summary: The aim of this study was to investigate the correlation between changes in water activity (a(w)) and variations in active fluorescent units (AFU) in probiotic products containing freeze-dried bacteria. The results showed that with an increase in a(w), the number of bacteria decreased, but the a(w) of the tested products did not exceed 0.15.
Review
Biochemistry & Molecular Biology
Aleksandra Ryl, Aleksandra Szylinska, Karolina Skonieczna-Zydecka, Tomasz Miazgowski, Iwona Rotter
Summary: The relationship between components of metabolic syndrome (MetS) and bone mineral density (BMD), particularly in men, remains unclear. This systematic review and meta-analysis found that adult males with MetS have normal bone mass at the femoral neck (FN) and lumbar spine (LS). However, due to heterogeneity in the analyzed studies and the absence of control groups, further research is needed to fully understand the associations between MetS and BMD in men.
Article
Health Care Sciences & Services
Slawomir Zacha, Aleksander Szwed, Jakub Miegon, Karolina Skonieczna-Zydecka, Agata Andrzejewska, Elzbieta Modrzejewska, Marcin Horecki, Konrad Jarosz, Jowita Biernawska
Summary: The aim of this study was to compare the quality of the perioperative period before and after the introduction of an interdisciplinary protocol in pediatric orthopedics. The study found that optimization of perioperative management using novel tools and the interdisciplinary ERAS protocol is possible and brings tangible benefits in psychological, organizational, and financial terms.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Pediatrics
Jakub Miegon, Slawomir Zacha, Karolina Skonieczna-Zydecka, Agata Wiczk-Bratkowska, Agata Andrzejewska, Konrad Jarosz, Monika Deptula-Jarosz, Jowita Biernawska
Summary: This study examined the efficacy of protocolised intraoperative hemodynamic monitoring and goal-directed therapy in adolescent idiopathic scoliosis patients undergoing posterior fusion surgery. The intervention group, which received targeted interventions during surgery, showed significant advantages in terms of hospital stay durations, episodes of hypotension, postoperative hemoglobin levels, and extubation times compared to the control group.