Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone

Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signaling

(2020) Lei Li et al.   Journal of Neuroinflammation

Drug-1,3,4-Thiadiazole Conjugates as Novel Mixed-Type Inhibitors of Acetylcholinesterase: Synthesis, Molecular Docking, Pharmacokinetics, and ADMET Evaluation

(2019) Rabail Ujan et al.   MOLECULES

Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches

(2019) Jin Han et al.   Nutrients

Selected essential oils inhibit key physiological enzymes and possess intracellular and extracellular antimelanogenic properties in vitro

(2018) Zaahira Aumeeruddy-Elalfi et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

(2018) Seungeun Lee et al.   MOLECULES

Potential application of zerumbone in the prevention and therapy of chronic human diseases

(2018) Yogendra Prakash Singh et al.   Journal of Functional Foods

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

(2015) Douglas E. V. Pires et al.   JOURNAL OF MEDICINAL CHEMISTRY

Toxicological evaluation of zerumbone on antitumor effects in mice

(2014) Bae Jin   African Journal of Pharmacy and Pharmacology

In vivo and In vitro Genotoxic Effects of Zerumbone

(2014) Adel S. Al-Zubairi et al.   CARYOLOGIA

Acute Toxicity Study of Zerumbone-Loaded Nanostructured Lipid Carrier on BALB/c Mice Model

(2014) Heshu Sulaiman Rahman et al.   Biomed Research International

Successes and Failures for Drugs in Late-Stage Development for Alzheimer’s Disease

(2013) Camryn Berk et al.   DRUGS & AGING

Butyrylcholinesterase and the cholinergic system

(2013) G.A. Reid et al.   NEUROSCIENCE

Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease

(2010) Margarita C Dinamarca et al.   Molecular Neurodegeneration

Computational toxicology—a tool for early safety evaluation

(2009) Cédric Merlot   DRUG DISCOVERY TODAY

Amyloid-cholinesterase interactions

(2008) Nibaldo C. Inestrosa et al.   FEBS Journal