期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 22, 期 17, 页码 5899-5903出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201600471
关键词
annulation; C-H activation; cobalt; heterocycles; homogeneous catalysis
资金
- DST-SERB, India [EMR/2014/000978]
- CSIR
The cyclization of substituted N-methoxy benzamides with alkynes in the presence of an easily affordable cobalt complex and NaOAc provides isoquinolone derivatives in good to excellent yields. The cyclization reaction is compatible with a range of functional group-substituted benzamides, as well as ester- and alcohol-substituted alkynes. The cobalt complex [(CoCp)-Cp-III*(OR)(2)] (R=Me or Ac) serves as an efficient catalyst for the cyclization reaction. Later, isoquinolone derivatives were converted into 1-chloro and 1-bromo substituted isoquinoline derivatives in excellent yields in the presence of POCl3 or PBr3.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据