Cholinergic midbrain afferents modulate striatal circuits and shape encoding of action strategies

Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson’s Disease Models

(2019) Asami Tanimura et al.   NEURON

Pedunculopontine glutamatergic neurons provide a novel source of feedforward inhibition in the striatum by selectively targeting interneurons

(2019) Maxime Assous et al.   JOURNAL OF NEUROSCIENCE

Striatal Low-Threshold Spiking Interneurons Regulate Goal-Directed Learning

(2019) Elizabeth N. Holly et al.   NEURON

Differential inputs to striatal cholinergic and parvalbumin interneurons imply functional distinctions

(2018) Jason R Klug et al.   eLife

Thalamic Control of Dorsomedial Striatum Regulates Internal State to Guide Goal-Directed Action Selection

(2017) Laura A. Bradfield et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin Interneurons Modulate Striatal Output and Enhance Performance during Associative Learning

(2017) Kwang Lee et al.   NEURON

Rethinking the Pedunculopontine Nucleus: From Cellular Organization to Function

(2017) Juan Mena-Segovia et al.   NEURON

The role of the intrinsic cholinergic system of the striatum: What have we learned from TAN recordings in behaving animals?

(2017) Paul Apicella   NEUROSCIENCE

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats

(2017) Jasjot Saund et al.   PSYCHOPHARMACOLOGY

Differential processing of thalamic information via distinct striatal interneuron circuits

(2017) Maxime Assous et al.   Nature Communications

Optogenetic excitation in the ventral tegmental area of glutamatergic or cholinergic inputs from the laterodorsal tegmental area drives reward

(2016) Stephan Steidl et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neostriatal GABAergic Interneurons Mediate Cholinergic Inhibition of Spiny Projection Neurons

(2016) Thomas W. Faust et al.   JOURNAL OF NEUROSCIENCE

Segregated cholinergic transmission modulates dopamine neurons integrated in distinct functional circuits

(2016) Daniel Dautan et al.   NATURE NEUROSCIENCE

Pedunculopontine tegmental nucleus lesions impair probabilistic reversal learning by reducing sensitivity to positive reward feedback

(2016) Anam Syed et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Aging-Related Dysfunction of Striatal Cholinergic Interneurons Produces Conflict in Action Selection

(2016) Miriam Matamales et al.   NEURON

Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation

(2016) Christina M. Gremel et al.   NEURON

Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways

(2016) Cheng Xiao et al.   NEURON

Distributed and Mixed Information in Monosynaptic Inputs to Dopamine Neurons

(2016) Ju Tian et al.   NEURON

Calcium imaging of sleep–wake related neuronal activity in the dorsal pons

(2016) Julia Cox et al.   Nature Communications

Pontomesencephalic Tegmental Afferents to VTA Non-dopamine Neurons Are Necessary for Appetitive Pavlovian Learning

(2016) Hau-Jie Yau et al.   Cell Reports

A comprehensive excitatory input map of the striatum reveals novel functional organization

(2016) Barbara J Hunnicutt et al.   eLife

A Closer Look at the Effects of Repeated Cocaine Exposure on Adaptive Decision-Making under Conditions That Promote Goal-Directed Control

(2016) Briac Halbout et al.   Frontiers in Psychiatry

Quantitative Imaging of Cholinergic Interneurons Reveals a Distinctive Spatial Organization and a Functional Gradient across the Mouse Striatum

(2016) Miriam Matamales et al.   PLoS One

Cholinergic interneurons in the dorsal and ventral striatum: anatomical and functional considerations in normal and diseased conditions

(2015) Kalynda K. Gonzales et al.   Annals of the New York Academy of Sciences

Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology

(2015) Moran Furman et al.   EPILEPSIA

Novel fast adapting interneurons mediate cholinergic-induced fast GABAAinhibitory postsynaptic currents in striatal spiny neurons

(2015) Thomas W. Faust et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Role of Striatal Cholinergic Interneurons in Set-Shifting in the Rat

(2015) S. Aoki et al.   JOURNAL OF NEUROSCIENCE

Enhanced consumption of salient solutions following pedunculopontine tegmental lesions

(2015) D.A.A. MacLaren et al.   NEUROSCIENCE

The M-current contributes to high threshold membrane potential oscillations in a cell type-specific way in the pedunculopontine nucleus of mice

(2015) Csilla Bordas et al.   Frontiers in Cellular Neuroscience

Decoding brain state transitions in the pedunculopontine nucleus: cooperative phasic and tonic mechanisms

(2015) Anne Petzold et al.   Frontiers in Neural Circuits

Whole-Brain Mapping of Inputs to Projection Neurons and Cholinergic Interneurons in the Dorsal Striatum

(2015) Qingchun Guo et al.   PLoS One

The role of pedunculopontine nucleus in choice behavior under risk

(2014) Mona Leblond et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Deficits in motor performance after pedunculopontine lesions in rats - impairment depends on demands of task

(2014) Duncan A. A. MacLaren et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cortical and Thalamic Excitation Mediate the Multiphasic Responses of Striatal Cholinergic Interneurons to Motivationally Salient Stimuli

(2014) N. M. Doig et al.   JOURNAL OF NEUROSCIENCE

A Major External Source of Cholinergic Innervation of the Striatum and Nucleus Accumbens Originates in the Brainstem

(2014) D. Dautan et al.   JOURNAL OF NEUROSCIENCE

Discharge Profiles across the Sleep-Waking Cycle of Identified Cholinergic, GABAergic, and Glutamatergic Neurons in the Pontomesencephalic Tegmentum of the Rat

(2014) S. Boucetta et al.   JOURNAL OF NEUROSCIENCE

Pedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons

(2014) S. Hong et al.   NEUROSCIENCE

Enhanced flexibility of place discrimination learning by targeting striatal cholinergic interneurons

(2014) Kana Okada et al.   Nature Communications

Cell-Specific Retrograde Signals Mediate Antiparallel Effects of Angiotensin II on Osmoreceptor Afferents to Vasopressin and Oxytocin Neurons

(2014) Tevye J. Stachniak et al.   Cell Reports

Reciprocal regulation of inhibitory synaptic transmission by nicotinic and muscarinic receptors in rat nucleus accumbens shell

(2013) Kiyofumi Yamamoto et al.   JOURNAL OF PHYSIOLOGY-LONDON

Updating of action–outcome associations is prevented by inactivation of the posterior pedunculopontine tegmental nucleus

(2013) Duncan A.A. MacLaren et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Differential Innervation of Direct- and Indirect-Pathway Striatal Projection Neurons

(2013) Nicholas R. Wall et al.   NEURON

The Thalamostriatal Pathway and Cholinergic Control of Goal-Directed Action: Interlacing New with Existing Learning in the Striatum

(2013) Laura A. Bradfield et al.   NEURON

Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions

(2013) Christina M. Gremel et al.   Nature Communications

Different dorsal striatum circuits mediate action discrimination and action generalization

(2012) Mónica Hilario et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Relationships between the Firing of Identified Striatal Interneurons and Spontaneous and Driven Cortical Activities In Vivo

(2012) A. Sharott et al.   JOURNAL OF NEUROSCIENCE

Input-specific control of reward and aversion in the ventral tegmental area

(2012) Stephan Lammel et al.   NATURE

Striatal Dopamine Release Is Triggered by Synchronized Activity in Cholinergic Interneurons

(2012) Sarah Threlfell et al.   NEURON

Striatal Cholinergic Interneurons Display Activity-Related Phosphorylation of Ribosomal Protein S6

(2012) Jesus Bertran-Gonzalez et al.   PLoS One

Selective Activation of Cholinergic Interneurons Enhances Accumbal Phasic Dopamine Release: Setting the Tone for Reward Processing

(2012) Roger Cachope et al.   Cell Reports

Cholinergic modulation of synaptic integration and dendritic excitability in the striatum

(2011) Ian Antón Oldenburg et al.   CURRENT OPINION IN NEUROBIOLOGY

The Role of Striatal Tonically Active Neurons in Reward Prediction Error Signaling during Instrumental Task Performance

(2011) P. Apicella et al.   JOURNAL OF NEUROSCIENCE

GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons

(2011) Daniel F English et al.   NATURE NEUROSCIENCE

Recombinase-Driver Rat Lines: Tools, Techniques, and Optogenetic Application to Dopamine-Mediated Reinforcement

(2011) Ilana B. Witten et al.   NEURON

Spontaneous firing and evoked pauses in the tonically active cholinergic interneurons of the striatum

(2011) J.A. Goldberg et al.   NEUROSCIENCE

Topographical Organization of the Pedunculopontine Nucleus

(2011) Cristina Martinez-Gonzalez et al.   Frontiers in Neuroanatomy

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Thalamic Gating of Corticostriatal Signaling by Cholinergic Interneurons

(2010) Jun B. Ding et al.   NEURON

Bar pressing for food: differential consequences of lesions to the anterior versus posterior pedunculopontine

(2009) David I. G. Wilson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Chronic Nicotine Selectively Enhances  4 2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway

(2009) C. Xiao et al.   JOURNAL OF NEUROSCIENCE

Different Pedunculopontine Tegmental Neurons Signal Predicted and Actual Task Rewards

(2009) K.-i. Okada et al.   JOURNAL OF NEUROSCIENCE

Recurrent Inhibitory Network among Striatal Cholinergic Interneurons

(2008) M. A. Sullivan et al.   JOURNAL OF NEUROSCIENCE

Acetylcholine activity in selective striatal regions supports behavioral flexibility

(2008) Michael E. Ragozzino et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Differential involvement of M1-type and M4-type muscarinic cholinergic receptors in the dorsomedial striatum in task switching

(2007) Martha F. McCool et al.   NEUROBIOLOGY OF LEARNING AND MEMORY