TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice

A new background subtraction method for Western blot densitometry band quantification through image analysis software

(2018) Gabriel Gallo-Oller et al.   JOURNAL OF IMMUNOLOGICAL METHODS

SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond

(2018) Russell A. DeBose-Boyd et al.   TRENDS IN BIOCHEMICAL SCIENCES

Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis

(2018) Sarah K. Williams et al.   Scientific Reports

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

Serum cell death biomarker mirrors liver cancer regression after transarterial chemoembolisation

(2016) B. Bock et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

Essential protective role of tumor necrosis factor receptor 2 in neurodegeneration

(2016) Yun Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease

(2015) Paul Angulo et al.   GASTROENTEROLOGY

Interferon-Mediated Cytokine Induction Determines Sustained Virus Control in Chronic Hepatitis C Virus Infection

(2015) Franziska Wandrer et al.   JOURNAL OF INFECTIOUS DISEASES

ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development

(2014) Hayato Nakagawa et al.   CANCER CELL

The pan-caspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in a murine model of non-alcoholic steatohepatitis

(2014) Fernando J. Barreyro et al.   LIVER INTERNATIONAL

p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene

(2013) Z He et al.   CELL DEATH AND DIFFERENTIATION

The multifaceted role of mTORC1 in the control of lipid metabolism

(2013) Stéphane J H Ricoult et al.   EMBO REPORTS

Pharmacological promotion of autophagy alleviates steatosis and injury in alcoholic and non-alcoholic fatty liver conditions in mice

(2013) Chih-Wen Lin et al.   JOURNAL OF HEPATOLOGY

A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice

(2013) T H Van Dijk et al.   LABORATORY ANIMALS

Antagonistic TNF Receptor One-Specific Antibody (ATROSAB): Receptor Binding and In Vitro Bioactivity

(2013) Fabian Richter et al.   PLoS One

Increased plasma levels of CK-18 as potential cell death biomarker in patients with HELLP syndrome

(2013) K John et al.   Cell Death & Disease

Increased apoptosis induction in hepatocellular carcinoma by a novel tumor-targeted TRAIL fusion protein combined with bortezomib

(2012) Kristin Wahl et al.   HEPATOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Distinct mTORC1 pathways for transcription and cleavage of SREBP-1c

(2012) W. J. Quinn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

(2012) M. S. Han et al.   SCIENCE

Mechanisms of Cell Death in Acute Liver Failure

(2012) Heike Bantel et al.   Frontiers in Physiology

TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE

(2011) Niki Tsakiri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

(2011) Núria Tarrats et al.   HEPATOLOGY

A TNF Receptor 2 Selective Agonist Rescues Human Neurons from Oxidative Stress-Induced Cell Death

(2011) Roman Fischer et al.   PLoS One

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression

(2010) Eek Joong Park et al.   CELL

High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis

(2010) Rohit Kohli et al.   HEPATOLOGY

An apoptosis panel for nonalcoholic steatohepatitis diagnosis

(2010) Tarek I. Abu-Rajab Tamimi et al.   JOURNAL OF HEPATOLOGY

ATROSAB, a humanized antagonistic anti-tumor necrosis factor receptor one-specific antibody

(2010) Kirstin A. Zettlitz et al.   mAbs

Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

(2009) Thomas Kaufmann et al.   IMMUNITY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance

(2008) Rajat Singh et al.   HEPATOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease

(2008) Harmeet Malhi et al.   SEMINARS IN LIVER DISEASE