Review
Virology
Dimitris Basoulis, Elpida Mastrogianni, Pantazis-Michail Voutsinas, Mina Psichogiou
Summary: The COVID-19 pandemic has had significant socio-economic impact globally, and people with HIV (PWH) are considered a vulnerable population due to immunosuppression and HIV stigma. This review summarizes the current understanding of the clinical implications of the overlap of the two epidemics. PWH share similar risk factors for severe COVID-19 as the general population, but virological and immunological status also play a role. Opportunities for HIV treatment are found in COVID-19 research, particularly in monoclonal antibody and vaccine development.
Article
Public, Environmental & Occupational Health
Mehmood Ahmad, Bilal Mahmood Beg, Arfa Majeed, Sadaf Areej, Sualeha Riffat, Muhammad Adil Rasheed, Sammina Mahmood, Rana Muhammad Zahid Mushtaq, Mian Abdul Hafeez
Summary: The study conducted in Pakistan aimed to determine the epidemiological and clinical characteristics of COVID-19 patients by analyzing data collected from various hospitals. The findings revealed that fever, cough, fatigue, dyspnea, and gastrointestinal discomfort were among the most frequently reported symptoms, with a majority of cases occurring in adults. The research also identified common comorbidities, median hospital stay duration, and factors contributing to the spread of the virus in Pakistan.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Infectious Diseases
David Chun-Ern Ng, Kah Kee Tan, Ling Chin, Marlindawati Mohd Ali, Ming Lee Lee, Fatin Mahirah Mahmood, Mohammad Faid Abd Rashid, Harlina Abdul Rashid, Erwin Jiayuan Khoo
Summary: In Negeri Sembilan, Malaysia, children with COVID-19 exhibited mild symptoms and a good prognosis, with 57.9% of cases being asymptomatic. Family clustering was identified as an important epidemiological feature in the outbreak, and the risk of transmission from children to guardians was minimal despite close contact.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Review
Cell Biology
Rameswari Chilamakuri, Saurabh Agarwal
Summary: The novel coronavirus (COVID-19) has significantly impacted the world since its emergence at the end of 2019, but there have been major advancements in our understanding of the virus and development of treatment options and vaccines to control the pandemic.
Article
Public, Environmental & Occupational Health
Warren Gavin, Elliott Campbell, Syed-Adeel Zaidi, Neha Gavin, Lana Dbeibo, Cole Beeler, Kari Kuebler, Ahmed Abdel-Rahman, Mark Luetkemeyer, Areeba Kara
Summary: This retrospective study evaluated COVID-19 patients admitted to one site in March 2020 and found that age and gender may impact disease outcomes. Certain biomarkers such as D-dimer, procalcitonin, lactate dehydrogenase, and BNP may serve as early indicators of disease trajectory.
AMERICAN JOURNAL OF INFECTION CONTROL
(2021)
Article
Virology
Alejandro Flores-Alanis, Zeus Saldana-Ahuactzi, Israel Parra-Ortega, Pablo Lopez-Ramirez, Marcela Salazar-Garcia, Yolanda P. Aleman-Garcia, Armando Cruz-Rangel, Alba Moreno-Paredes, Adrian Diaz-Rojas, Carmen Maldonado-Bernal, Jessica Quevedo-Moran, Victor M. Luna-Pineda
Summary: Children and adolescents in Mexico had low incidence and mortality during the first two years of the COVID-19 pandemic. While they are a heterogeneous population, many patients had comorbidities and symptoms similar to adults, as well as low viral load and IgG antibody levels.
Article
Virology
David A. Forero-Pena, Fhabian S. Carrion-Nessi, Daniela L. Mendoza-Millan, Oscar D. Omana-Avila, Mario D. Mejia-Bernard, Natasha A. Camejo-Avila, David M. Flora-Noda, Viledy L. Velasquez, Fabian R. Chacon-Labrador, Juan M. Doval-Fernandez, Andrea L. Maricuto, Maria E. Grillet, Juan V. Hernandez-Villena, Maria F. Vincenti-Gonzalez, Alberto E. Paniz-Mondolfi, Jose Orejas, Veronica Rodriguez, Mariana B. Contreras, Rafael N. Guevara, Martin Carballo, Jocays Caldera, Maria C. Redondo, Maria E. Landaeta
Summary: This study conducted a retrospective analysis of COVID-19 cases in Venezuela during the first epidemic wave, revealing that severe/critical patients were mostly older males with low education levels. Severe/critical patients had significantly higher levels of biochemical markers compared to those with mild/moderate disease. The overall mortality rate was 7.6%, with an expected increase in fatalities in the coming months.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Oncology
Xiangyi Kong, Yihang Qi, Junjie Huang, Yang Zhao, Yongle Zhan, Xuzhen Qin, Zhihong Qi, Adejare (Jay) Atanda, Lei Zhang, Jing Wang, Yi Fang, Peng Jia, Asieh Golozar, Lin Zhang, Yu Jiang
Summary: The overall prevalence of cancer among COVID-19 patients is low, but higher in Europe. Cancer prevalence is higher in patients aged over 60. The severity and mortality rates in COVID-19 patients with cancer are relatively high, especially in Europe.
Article
Virology
Danah Alsharrah, Fatemah Alhaddad, Munirah Alyaseen, Sarah Aljamaan, Nahar Almutairi, Mariam Ayed, Jesse Papenburg, Mohammad Alghounaim
Summary: A study in Kuwait found that nearly 70% of children with COVID-19 were asymptomatic. Children, regardless of symptoms, showed substantial duration of viral shedding. Among symptomatic patients, the disease seemed to be mild.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Olga Toscano, Nicola Cosentino, Jeness Campodonico, Antonio L. Bartorelli, Giancarlo Marenzi
Summary: During the COVID-19 pandemic, the hospitalization rate for patients with acute myocardial infarction (AMI) has significantly declined, leading to late arrivals and increased in-hospital mortality. There is still a lack of consensus on the most appropriate healthcare management pathway for AMI patients during the pandemic, highlighting the need for shared guidance.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Microbiology
Ran Jia, Lijuan Lu, Liyun Su, Ziyan Lin, Da Gao, Haiyan Lv, Menghua Xu, Pengcheng Liu, Lingfeng Cao, Jin Xu
Summary: This paper analyzed RSV-positive patients in the Children's Hospital of Fudan University from October 2019 to October 2021 and compared the clinical features before and during COVID-19. The study found an atypical upsurge of RSV infection in the late summer of 2021 after a major suppression in 2020. Males and infants aged under 5 months were the main populations infected with RSV. Less severe clinical outcomes were observed in patients during COVID-19 than before the pandemic.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Immunology
Yun Wang, Ying Liu, James Struthers, Min Lian
Summary: The study investigated the dynamics of the COVID-19 epidemic by detecting weekly hotspots of newly confirmed cases and quantifying the trends of incidence by county characteristics. While the COVID-19 incidence significantly decreased in the Northeast after a national plateau in early April, it continued increasing in the Midwest, South, and West regions. Higher risks of clustering and incidence were consistently observed in metropolitan counties, counties closest to core airports, most populous counties, and counties with higher proportion of racial/ethnic minorities.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Nobuaki Matsunaga, Kayoko Hayakawa, Mari Terada, Hiroshi Ohtsu, Yusuke Asai, Shinya Tsuzuki, Setsuko Suzuki, Ako Toyoda, Kumiko Suzuki, Mio Endo, Naoki Fujii, Michiyo Suzuki, Sho Saito, Yukari Uemura, Taro Shibata, Masashi Kondo, Kazuo Izumi, Junko Terada-Hirashima, Ayako Mikami, Wataru Sugiura, Norio Ohmagari
Summary: This study in Japan examined hospitalized patients with COVID-19, finding that they are typically middle-aged males with close contact to confirmed or suspected cases. The most common comorbidities were hypertension and diabetes. Most patients admitted were nonsevere cases, with a majority not requiring oxygen support during hospitalization.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Multidisciplinary Sciences
Tatjana Meister, Heti Pisarev, Raivo Kolde, Ruth Kalda, Kadri Suija, Lili Milani, Liis Karo-Astover, Marko Piirsoo, Anneli Uuskula
Summary: This retrospective cohort study analyzed nationwide e-health databases in Estonia to identify risk factors for SARS-CoV-2 infection and severe COVID-19. The study found that women, individuals with comorbid conditions or obesity, were more likely to be infected. Male sex, increasing age, and comorbid burden were significantly associated with more severe COVID-19 outcomes. Renal disease, previous myocardial infarction, and obesity were the strongest contributors to critical illness, while renal disease, cancer, liver disease, and cerebrovascular disease were the strongest contributors to a lethal outcome.
Article
Environmental Sciences
Wen Wen, Longbo Shi, Ling Li, Lina Wang, Jianmin Chen
Summary: During the COVID-19 pandemic, China adopted strategies to reduce human and economic loss. This study analyzed aerosol samples collected in Shanghai before and after the outbreak using HPLC-Q-TOF-MS. The results showed changes in the chemical compositions of the aerosols, with a decrease in certain compounds and an increase in aliphatic compounds. The study also found that the contribution of anthropogenic emissions in Shanghai decreased after the COVID-19 outbreak.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)