Mesenchymal stromal cells induce regulatory T cells via epigenetic conversion of human conventional CD4 T cells in vitro

Molecular Markers Distinguishing T Cell Subtypes With TSDR Strand-Bias Methylation

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Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

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Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3highregulatory T cells in humans

(2015) Makoto Miyara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel upstream enhancer ofFOXP3, sensitive to methylation-induced silencing, exhibits dysregulated methylation in rheumatoid arthritis Treg cells

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Immunomodulation of mesenchymal stromal cells on regulatory T cells and its possible mechanism

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Methylated DNA is over-represented in whole-genome bisulfite sequencing data

(2014) Lexiang Ji et al.   Frontiers in Genetics

Human mesenchymal stem cells from the umbilical cord matrix: Successful isolation and ex vivo expansion using serum-/xeno-free culture media

(2013) Irina N. Simões et al.   Biotechnology Journal

Human adipose-tissue derived mesenchymal stem cells induce functionalde-novoregulatory T cells with methylatedFOXP3gene DNA

(2013) A. U. Engela et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Multipotent stromal cells induce human regulatory T cells through a novel pathway involving skewing of monocytes toward anti-inflammatory macrophages

(2013) Sara M. Melief et al.   STEM CELLS

Allogenicity of Human Cardiac Stem/Progenitor Cells Orchestrated by Programmed Death Ligand 1

(2012) Laura Lauden et al.   CIRCULATION RESEARCH

Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction

(2012) Beatrice Del Papa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The impact of inflammatory licensing on heme oxygenase-1-mediated induction of regulatory T cells by human mesenchymal stem cells

(2011) D. Mougiakakos et al.   BLOOD

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Immunoregulatory effects of human dental pulp-derived stem cells on T cells: comparison of transwell co-culture and mixed lymphocyte reaction systems

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Therapeutic potential of intravenously administered human mesenchymal stromal cells

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The PDL1-PD1 Axis Converts Human TH1 Cells into Regulatory T Cells

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Immune regulatory properties of multipotent mesenchymal stromal cells: Where do we stand?

(2011) Ênio José Bassi   World Journal of Stem Cells

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

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Mesenchymal stem cell as salvage treatment for refractory chronic GVHD

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GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells

(2010) Gongxian Liao et al.   INTERNATIONAL IMMUNOLOGY

Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation

(2010) Ken-ichi Matsuoka et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

Human Adipose Tissue-Derived Mesenchymal Stem Cells Induce Explosive T-Cell Proliferation

(2010) Meindert J. Crop et al.   STEM CELLS AND DEVELOPMENT

Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells

(2009) K. English et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mesenchymal stromal cells promote or suppress the proliferation of T lymphocytes from cord blood and peripheral blood: the importance of low cell ratio and role of interleukin-6

(2009) Mehdi Najar et al.   CYTOTHERAPY

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

(2009) Loise M. Francisco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells

(2008) Hanna Igarashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A critical role of IFNγ in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1

(2008) Huiming Sheng et al.   CELL RESEARCH

DNA methylation controls Foxp3 gene expression

(2008) Julia K. Polansky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mesenchymal cells recruit and regulate T regulatory cells

(2008) M DIIANNI   EXPERIMENTAL HEMATOLOGY

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS