期刊
CHEMISTRY LETTERS
卷 45, 期 8, 页码 997-999出版社
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.160388
关键词
Graphene quantum dot (GQD); Photodynamic therapy; Reactive oxygen species (ROS)
资金
- Technology Innovation Program - Ministry of Trade, Industry & Energy (MI, Korea) [10054687]
- National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [NRF-2015R1D1A1A09060567, NRF-2014R1A2A2A03004802]
- Korea Evaluation Institute of Industrial Technology (KEIT) [10054687] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
In this study, we report the enhanced photodynamic therapeutic (PDT) activity of Chlorin e6 (Ce6)-loaded graphene quantum dots (GQDs). GQDs reinforced the Ce6 loading, solubility, and fluorescence in aqueous media and enhanced ROS production and cancer cell death. This GQDs conjugated Ce6 could be a good platform for imaging-guided cancer therapy.
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