Time Course of Changes in Sorafenib‐Treated Hepatocellular Carcinoma Cells Suggests Involvement of Phospho‐Regulated Signaling in Ferroptosis Induction

The influence of hypoxia and IFN-γ on the proteome and metabolome of therapeutic mesenchymal stem cells

(2018) Holly M. Wobma et al.   BIOMATERIALS

The iron chaperone poly(rC)-binding protein 2 forms a metabolon with the heme oxygenase 1/cytochrome P450 reductase complex for heme catabolism and iron transfer

(2017) Izumi Yanatori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT

(2017) Yuchao Gu et al.   MOLECULAR CELL

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Quantitative proteomics and phosphoproteomics on serial tumor biopsies from a sorafenib-treated HCC patient

(2016) Eva Dazert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

(2016) Tanja Krainz et al.   ACS Central Science

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

(2015) Min-Young Kwon et al.   Oncotarget

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

(2014) Scott J Dixon et al.   eLife

Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib

(2013) Christophe Louandre et al.   INTERNATIONAL JOURNAL OF CANCER

pLogo: a probabilistic approach to visualizing sequence motifs

(2013) Joseph P O'Shea et al.   NATURE METHODS

Quantitative Phosphoproteomics Reveal mTORC1 Activates de Novo Pyrimidine Synthesis

(2013) A. M. Robitaille et al.   SCIENCE

1D and 2D annotation enrichment: a statistical method integrating quantitative proteomics with complementary high-throughput data

(2012) Juergen Cox et al.   BMC BIOINFORMATICS

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation

(2009) Rosario Amato et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

(2008) Wan Seok Yang et al.   CHEMISTRY & BIOLOGY

A Cytosolic Iron Chaperone That Delivers Iron to Ferritin

(2008) H. Shi et al.   SCIENCE