A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle

Unspinning chromatin: Revealing the dynamic nucleosome landscape by NMR

(2019) Clara van Emmerik et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Chemical methods for the modification of RNA

(2019) Marie Flamme et al.   METHODS

Structural basis of specific H2A K13/K15 ubiquitination by RNF168

(2019) Velten Horn et al.   Nature Communications

NMR Chemical Exchange Measurements Reveal That N6-Methyladenosine Slows RNA Annealing

(2019) Honglue Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigating the Dynamics of Destabilized Nucleosomes Using Methyl-TROSY NMR

(2018) Julianne L. Kitevski-LeBlanc et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR Studies of Large Proteins

(2017) Yajun Jiang et al.   JOURNAL OF MOLECULAR BIOLOGY

Histone octamer rearranges to adapt to DNA unwrapping

(2017) Silvija Bilokapic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Synthesis and incorporation of 13C-labeled DNA building blocks to probe structural dynamics of DNA by NMR

(2017) Felix Nußbaumer et al.   NUCLEIC ACIDS RESEARCH

Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler

(2017) Kalyan K. Sinha et al.   SCIENCE

Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions

(2017) Vojč Kocman et al.   Nature Communications

Histone octamer rearranges to adapt to DNA unwrapping

(2017) Silvija Bilokapic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

(2017) Julianne Kitevski-LeBlanc et al.   eLife

Isotope-labeling strategies for solution NMR studies of macromolecular assemblies

(2016) Heyi Zhang et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation

(2016) Shunsuke Imai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stable isotope labeling methods for DNA

(2016) Frank H.T. Nelissen et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability

(2016) Thuy T. M. Ngo et al.   Nature Communications

An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation

(2016) Shunsuke Imai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Dynamic molecular basis for malfunction in disease mutants of p97/VCP

(2016) Anne K Schuetz et al.   eLife

Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation

(2016) Yoshifumi Fujii et al.   FEBS Open Bio

13CHD2–CEST NMR spectroscopy provides an avenue for studies of conformational exchange in high molecular weight proteins

(2015) Enrico Rennella et al.   JOURNAL OF BIOMOLECULAR NMR

Visualizing transient Watson–Crick-like mispairs in DNA and RNA duplexes

(2015) Isaac J. Kimsey et al.   NATURE

Synthesis and applications of RNAs with position-selective labelling and mosaic composition

(2015) Yu Liu et al.   NATURE

Structure of the HIV-1 RNA packaging signal

(2015) S. C. Keane et al.   SCIENCE

Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR

(2014) Rina Rosenzweig et al.   Annual Review of Biochemistry

Present and future of NMR for RNA–protein complexes: A perspective of integrated structural biology

(2014) Teresa Carlomagno   JOURNAL OF MAGNETIC RESONANCE

DNA Methylation Regulated Nucleosome Dynamics

(2013) Isabel Jimenez-Useche et al.   Scientific Reports

A 2D 13C-CEST experiment for studying slowly exchanging protein systems using methyl probes: an application to protein folding

(2012) Guillaume Bouvignies et al.   JOURNAL OF BIOMOLECULAR NMR

Histone H4 K16Q Mutation, an Acetylation Mimic, Causes Structural Disorder of Its N-Terminal Basic Patch in the Nucleosome

(2012) Bing-Rui Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of the yeast U2/U6 snRNA complex

(2012) J. E. Burke et al.   RNA

Prediction of Hydrodynamic and Other Solution Properties of Rigid Proteins from Atomic- and Residue-Level Models

(2011) A. Ortega et al.   BIOPHYSICAL JOURNAL

An Optimized Relaxation-Based Coherence Transfer NMR Experiment for the Measurement of Side-Chain Order in Methyl-Protonated, Highly Deuterated Proteins

(2011) Hechao Sun et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Effects of DNA Methylation on the Structure of Nucleosomes

(2011) Ju Yeon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cytosine methylation alters DNA mechanical properties

(2011) Philip M. D. Severin et al.   NUCLEIC ACIDS RESEARCH

Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR

(2011) H. Kato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optimal methyl labeling for studies of supra-molecular systems

(2010) Tomasz L. Religa et al.   JOURNAL OF BIOMOLECULAR NMR

Structure of a Conserved Retroviral RNA Packaging Element by NMR Spectroscopy and Cryo-Electron Tomography

(2010) Yasuyuki Miyazaki et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystal Structures of Nucleosome Core Particles Containing the ‘601’ Strong Positioning Sequence

(2010) Dileep Vasudevan et al.   JOURNAL OF MOLECULAR BIOLOGY

DNA Methylation Increases Nucleosome Compaction and Rigidity

(2010) John S. Choy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

Dynamic Regulation of Archaeal Proteasome Gate Opening As Studied by TROSY NMR

(2010) T. L. Religa et al.   SCIENCE

Isotope labeling strategies for NMR studies of RNA

(2009) Kun Lu et al.   JOURNAL OF BIOMOLECULAR NMR

Characterization of the N-Terminal Tail Domain of Histone H3 in Condensed Nucleosome Arrays by Hydrogen Exchange and NMR

(2009) Hidenori Kato et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY