Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis

Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina

(2019) Yi-Rong Peng et al.   CELL

Mendelian genes in primary open angle glaucoma

(2019) Nathan C. Sears et al.   EXPERIMENTAL EYE RESEARCH

Update on the genetics of primary open-angle glaucoma

(2019) Hannah Youngblood et al.   EXPERIMENTAL EYE RESEARCH

How many aqueous humor outflow pathways are there?

(2019) Ciro Costagliola et al.   SURVEY OF OPHTHALMOLOGY

Cell-Type-Specific Complement Expression in the Healthy and Diseased Retina

(2019) Diana Pauly et al.   Cell Reports

The primate model for understanding and restoring vision

(2019) Serge Picaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptome analysis of adult and fetal trabecular meshwork, cornea, and ciliary body tissues by RNA sequencing

(2018) Megan Ulmer Carnes et al.   EXPERIMENTAL EYE RESEARCH

Genome-wide association analyses identify new loci influencing intraocular pressure

(2018) X Raymond Gao et al.   HUMAN MOLECULAR GENETICS

A Common Glaucoma-risk Variant of SIX6 Alters Retinal Nerve Fiber Layer and Optic Disc Measures in a European Population

(2018) Anthony P. Khawaja et al.   JOURNAL OF GLAUCOMA

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

(2018) Stuart MacGregor et al.   NATURE GENETICS

A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci

(2018) Hélène Choquet et al.   Nature Communications

Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis

(2018) Ting Xie et al.   Cell Reports

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

(2018) Rebecca King et al.   PLoS Genetics

CD163+ macrophages infiltrate axon bundles of postmortem optic nerves with glaucoma

(2018) Milica A. Margeta et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

The many faces of the trabecular meshwork cell

(2017) W. Daniel Stamer et al.   EXPERIMENTAL EYE RESEARCH

Primary congenital and developmental glaucomas

(2017) Carly J. Lewis et al.   HUMAN MOLECULAR GENETICS

Genetics of glaucoma

(2017) Janey L. Wiggs et al.   HUMAN MOLECULAR GENETICS

Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci

(2017) Tin Aung et al.   NATURE GENETICS

The eye as a complement dysregulation hotspot

(2017) Simon J. Clark et al.   Seminars in Immunopathology

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Heterogeneity in the lymphatic vascular system and its origin

(2016) Maria H. Ulvmar et al.   CARDIOVASCULAR RESEARCH

Stem Cells in the Trabecular Meshwork for Regulating Intraocular Pressure

(2016) Hongmin Yun et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study

(2016) Todd E. Scheetz et al.   OPHTHALMOLOGY

The aqueous humor outflow pathways in glaucoma: A unifying concept of disease mechanisms and causative treatment

(2015) Barbara M. Braunger et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities

(2015) Kimberly A. Fernandes et al.   EXPERIMENTAL EYE RESEARCH

The Pathophysiology and Treatment of Glaucoma

(2014) Robert N. Weinreb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A lymphatic defect causes ocular hypertension and glaucoma in mice

(2014) Benjamin R. Thomson et al.   JOURNAL OF CLINICAL INVESTIGATION

The Schlemm’s canal is a VEGF-C/VEGFR-3–responsive lymphatic-like vessel

(2014) Aleksanteri Aspelund et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of plasmalemma vesicle-associated protein (PLVAP) in endothelial cells of Schlemm's canal and ocular capillaries

(2012) Leonie Herrnberger et al.   EXPERIMENTAL EYE RESEARCH

Gene Expression and Functional Annotation of the Human Ciliary Body Epithelia

(2012) Sarah F. Janssen et al.   PLoS One

Monocyte Modulation of Aqueous Outflow and Recruitment to the Trabecular Meshwork Following Selective Laser Trabeculoplasty

(2010) Jorge A. Alvarado   ARCHIVES OF OPHTHALMOLOGY

Stem cells in the trabecular meshwork: Present and future promises

(2009) M.J. Kelley et al.   EXPERIMENTAL EYE RESEARCH

The trabecular meshwork outflow pathways: Structural and functional aspects

(2009) Ernst R. Tamm   EXPERIMENTAL EYE RESEARCH

Extracellular matrix in the trabecular meshwork

(2008) Ted S. Acott et al.   EXPERIMENTAL EYE RESEARCH

Role of CYP1B1 in Glaucoma

(2007) Vasilis Vasiliou et al.   Annual Review of Pharmacology and Toxicology