p53 dependent LGR5 inhibition and caspase 3 activation are critically involved in apoptotic effect of compound K and its combination therapy potential in HCT116 cells

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

(2019) Stephanie A. Bien et al.   HUMAN GENETICS

LGR5 expression predicts peritoneal recurrence after curative resection of primary colon cancer

(2019) Hiroshi Nagata et al.   BRITISH JOURNAL OF CANCER

p53-Dependent Apoptotic Effect of Puromycin via Binding of Ribosomal Protein L5 and L11 to MDM2 and its Combination Effect with RITA or Doxorubicin

(2019) Jung et al.   Cancers

Oncogenic effect of PHLDB2 is associated with epithelial–mesenchymal transition and E-cadherin regulation in colorectal cancer

(2019) Geng Chen et al.   Cancer Cell International

Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?

(2018) RG Morgan et al.   BRITISH JOURNAL OF CANCER

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

(2018) Mark A Jenkins et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Zinc finger protein 746 promotes colorectal cancer progression via c-Myc stability mediated by glycogen synthase kinase 3β and F-box and WD repeat domain-containing 7

(2018) Ji Hoon Jung et al.   ONCOGENE

Incidence patterns of colorectal cancers in four countries of the Middle East Cancer Consortium (Cyprus, Jordan, Israel, and İzmir, Turkey) compared with those in the United States Surveillance, Epidemiology, and End Results Program

(2018) Sultan Eser et al.   Turkish Journal of Gastroenterology

Compound K induced apoptosis via endoplasmic reticulum Ca 2+ release through ryanodine receptor in human lung cancer cells

(2018) Dong-Hyun Shin et al.   Journal of Ginseng Research

LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/β-catenin pathway and predicts poor survival of glioma patients

(2018) Jin Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Radix Tetrastigma hemsleyani flavone exhibits antitumor activity in colorectal cancer via Wnt/β-catenin signaling pathway

(2018) Xiaowei Wu et al.   OncoTargets and Therapy

PIN1 in Cell Cycle Control and Cancer

(2018) Chi-Wai Cheng et al.   Frontiers in Pharmacology

Visualization and targeting of LGR5+ human colon cancer stem cells

(2017) Mariko Shimokawa et al.   NATURE

Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation

(2016) Lei Chen et al.   Cell Death & Disease

Effects of ginsenoside compound K combined with cisplatin on the proliferation, apoptosis and epithelial mesenchymal transition in MCF-7 cells of human breast cancer

(2015) Keqiang Zhang et al.   PHARMACEUTICAL BIOLOGY

MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of β-catenin signaling

(2014) J. X. Zhang et al.   ANNALS OF ONCOLOGY

Curcumin Promotes Autophagic Survival of a Subset of Colon Cancer Stem Cells, Which Are Ablated by DCLK1-siRNA

(2014) C. Kantara et al.   CANCER RESEARCH

Compound K-induced apoptosis of human hepatocellular carcinoma MHCC97-H cells in vitro

(2014) ZHI-ZHONG ZHENG et al.   ONCOLOGY REPORTS

Structure and function of LGR5: An enigmatic G-protein coupled receptor marking stem cells

(2014) Kaavya Krishna Kumar et al.   PROTEIN SCIENCE

Methanolic Extracts of Bitter Melon Inhibit Colon Cancer Stem Cells by Affecting Energy Homeostasis and Autophagy

(2013) Deep Kwatra et al.   Evidence-based Complementary and Alternative Medicine

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology