Shared neoantigens: ideal targets for off-the-shelf cancer immunotherapy

Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia

(2019) Dyantha I. van der Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers

(2019) Parisa Malekzadeh et al.   JOURNAL OF CLINICAL INVESTIGATION

DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and Immunogenicity

(2019) Jingcheng Wu et al.   Frontiers in Immunology

Personalized neoantigen vaccines: A new approach to cancer immunotherapy

(2018) Amanda R. Aldous et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Comprehensive Characterization of Cancer Driver Genes and Mutations

(2018) Matthew H. Bailey et al.   CELL

MHCflurry: Open-Source Class I MHC Binding Affinity Prediction

(2018) Timothy J. O'Donnell et al.   Cell Systems

TSNAdb: A Database for Tumor-specific Neoantigens from Immunogenomics Data Analysis

(2018) Jingcheng Wu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Actively personalized vaccination trial for newly diagnosed glioblastoma

(2018) Norbert Hilf et al.   NATURE

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

(2018) Derin B. Keskin et al.   NATURE

Shared cancer neoantigens: Making private matters public

(2017) Christopher A. Klebanoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

(2017) Ugur Sahin et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

T-Cell Transfer Therapy Targeting Mutant KRAS

(2017)   NEW ENGLAND JOURNAL OF MEDICINE

PSSMHCpan: a novel PSSM-based software for predicting class I peptide-HLA binding affinity

(2017) Geng Liu et al.   GigaScience

TSNAD: an integrated software for cancer somatic mutation and tumour-specific neoantigen detection

(2017) Zhan Zhou et al.   Royal Society Open Science

T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer

(2016) Eric Tran et al.   NEW ENGLAND JOURNAL OF MEDICINE

COSMIC: somatic cancer genetics at high-resolution

(2016) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Gapped sequence alignment using artificial neural networks: application to the MHC class I system

(2015) Massimo Andreatta et al.   BIOINFORMATICS

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes

(2015) Andrew D. Skora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Immunogenicity of somatic mutations in human gastrointestinal cancers

(2015) E. Tran et al.   SCIENCE

Identification of T-cell Receptors Targeting KRAS-Mutated Human Tumors

(2015) Q. J. Wang et al.   Cancer Immunology Research

Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer

(2014) E. Tran et al.   SCIENCE

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

(2014) J. Zhang et al.   SCIENCE

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of CD8+ T Cell Epitopes in the West Nile Virus Polyprotein by Reverse-Immunology Using NetCTL

(2010) Mette Voldby Larsen et al.   PLoS One

NetMHCpan, a method for MHC class I binding prediction beyond humans

(2008) Ilka Hoof et al.   IMMUNOGENETICS