Article
Economics
Ben A. van Hout, James W. Shaw
Summary: This research developed algorithms to map EQ-5D-3L responses to EQ-5D-5L value sets and found that including indicants of problems for other dimensions as regressors in the model improved prediction accuracy. Adding age and gender lowered AIC without improving predictions, while including a latent factor slightly improved predictive accuracy. Models conditioning on problems in other dimensions yielded more accurate predictions than an alternative copula-based approach.
Article
Economics
Sarah Dewilde, Bram Roudijk, Nafthali H. Tollenaar, Juan M. Ramos-Goni
Summary: This study aimed to obtain a value set for EQ-5D-Y-3L in Belgium by conducting Composite Time Trade-Off interviews and an online discrete choice experiment survey with a sample of adults. The results revealed preferences for health states in children and adolescents, with pain/discomfort being identified as the most important health dimension.
Article
Economics
Valentina Prevolnik Rupel, Juan M. Ramos-Goni, Marko Ogorevc, Simone Kreimeier, Kristina Ludwig, Wolfgang Greiner
Summary: This study compared preferences for EQ-5D-Y-3L obtained from adolescents and adults considering a hypothetical 10-year-old child in Germany, Slovenia, and Spain. Adolescents tend to prioritize mobility and self-care, while giving less importance to anxiety/depression. Differences were observed in the rank-order of dimension levels between adults and adolescents in all 3 countries.
Article
Economics
Bram Roudijk, Ayesha Sajjad, Brigitte Essers, Stefan Lipman, Peep Stalmeier, Aureliano Paolo Finch
Summary: This study collected preferences for the child-friendly EQ-5D version, EQ-5D-Y-3L, using composite time trade-off and discrete choice experiment methods. The study generated a Dutch value set for EQ-5D-Y-3L, which can be used in economic evaluations of healthcare interventions for paediatric populations. The results showed that pain/discomfort had the highest weight, followed by feeling worried, sad or unhappy, usual activities, mobility, and self-care.
Article
Health Care Sciences & Services
David J. Mott, Koonal K. Shah, Juan Manuel Ramos-Goni, Nancy J. Devlin, Oliver Rivero-Arias
Summary: This study compared the preferences of adults and adolescents for EQ-5D-Y-3L health states and found that pain/discomfort was the most important for both samples. Adolescents gave less weight to usual activities, pain/discomfort, and anxiety/depression compared to adults. The results suggest potential differences in preferences between adolescents and adults when evaluating children's health.
MEDICAL DECISION MAKING
(2021)
Article
Health Care Sciences & Services
Titi Sahidah Fitriana, Fredrick Dermawan Purba, Rina Rahmatika, Riski Muhaimin, Nur Melani Sari, Gouke Bonsel, Elly Stolk, Jan J. Busschbach
Summary: This study compared the measurement properties and responsiveness of EQ-5D-Y-3L and EQ-5D-Y-5L in pediatric patients. The results showed that the feasibility, convergent validity, and disease-specific measures were similar between the two versions, but EQ-5D-Y-5L had better test-retest reliability and sensitivity for detecting health changes.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2021)
Article
Health Care Sciences & Services
Vitaly Omelyanovskiy, Nuriya Musina, Svetlana Ratushnyak, Tatiana Bezdenezhnykh, Vlada Fediaeva, Bram Roudijk, Fredrick Dermawan Purba
Summary: This study aimed to establish an EQ-5D-3L value set for Russia by recruiting a representative sample from the general population, conducting face-to-face interviews, and utilizing both time trade-off and discrete choice experiment techniques. A hybrid regression model was used to estimate the value set, highlighting the significant impact of mobility and the lowest impact of anxiety/depression on utility decrement.
QUALITY OF LIFE RESEARCH
(2021)
Article
Economics
Fanni Rencz, Gabor Ruzsa, Alex Bato, Zhihao Yang, Aureliano Paolo Finch, Valentin Brodszky
Summary: This study aimed to develop a national value set of the EQ-5D-Y-3L for Hungary. The results showed that the severity of different domains had different impacts on utilities, with pain or discomfort being the most important factor. The findings of this study are important for evaluating the cost utility of health technologies for children and adolescents in Hungary.
Article
Health Care Sciences & Services
Titi Sahidah Fitriana, Fredrick Dermawan Purba, Elly Stolk, Jan J. Busschbach
Summary: Background: Self-report is the standard method for measuring health-related quality of life (HRQoL) in children, but sometimes children are unable to report their own health. This study investigated the agreement between self-report and proxy-report measures of HRQoL in children using the EQ-5D-Y questionnaire. The study also explored the potential benefits of extending the response levels of the proxy questionnaire from 3 to 5.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Oncology
Nasrin Moradi, Thomas G. Poder, Hossein Safari, Mohammad M. Mojahedian, Hosein Ameri
Summary: This study aimed to test the validity and reliability of the EQ-5D-5L (5L) in cancer patients compared to EQ-5D-3L (3L). The results showed that compared to 3L, 5L performed better in terms of ceiling effect, inconsistency, discriminatory power, convergent validity, and relative efficiency.
FRONTIERS IN ONCOLOGY
(2022)
Article
Economics
Zhihao Yang, Jie Jiang, Pei Wang, Xuejing Jin, Jing Wu, Yu Fang, Da Feng, Xiaoyu Xi, Shunping Li, Mingxia Jing, Bin Zheng, Weidong Huang, Nan Luo
Summary: This study established an EQ-5D-Y-3L value set for China following the international protocol. By using a larger cTTO design, the role of cTTO data in estimating the value set was better understood.
Article
Economics
Vivian Reckers-Droog, Milad Karimi, Stefan Lipman, Janine Verstraete
Summary: This study examines the reasons underlying the differences in adults' health-state preferences for themselves, a 10-year-old child, and 15-year-old adolescent. The results indicate that these differences largely result from differences in thoughts about nonhealth-related factors.
Article
Health Care Sciences & Services
Elena Olariu, Raluca Caplescu, Luke Vale, Ileana Gabriela Niculescu-Aron, Yemi Oluboyede, Marian Sorin Paveliu
Summary: The study aimed to estimate population norms for the Romanian versions of EQ-5D-5L, EQ-5D-3L, their indexes, and EQ VAS. A cross-sectional survey was conducted using a representative sample, and descriptive statistics were used to estimate population norms by age groups and sex. The findings provide reference values for healthcare professionals, researchers, and decision-makers in Romania.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2023)
Article
Pediatrics
Richard Huan Xu, Liling Zhu, Rongjia Sun, Rachel Lee-Yin Tan, Nan Luo, Sainan Zou, Dong Dong
Summary: This study evaluated and compared the psychometric properties of EQ-5D-Y-3L, EQ-5D-Y-5L, CHU-9D, and PedsQL in Chinese children and adolescents with osteogenesis imperfecta. The results showed that EQ-5D-Y-5L performed better than EQ-5D-Y-3L in terms of acceptability, convergent validity, and discriminatory power.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Economics
S. A. Lipman, V. T. Reckers-Droog, M. Karimi, M. Jakubczyk, A. E. Attema
Summary: The study surveyed 205 students to evaluate EQ-5D-Y-3L health states from different perspectives, finding that different perspectives had an impact on the outcomes, precision, and quality of the evaluation.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2021)
Article
Economics
Juan M. Ramos-Goni, Mark Oppe, Anabel Estevez-Carrillo, Oliver Rivero-Arias, I. M. P. A. C. T. H. T. A. HRQoL Group IMPACT HTA HRQoL Grp
Summary: This study aims to explore modeling strategies for generating EQ-5D-Y value sets and produce a Spanish value set. The results suggest that hybrid models using all available C-TTO observations produce a narrower range of values than the pits state anchoring approach. The international EQ-5D-Y valuation protocol should be updated to include different health states for the C-TTO experiment if alternative anchoring approaches are desired.
Article
Economics
Tessa Peasgood, Clara Mukuria, John Brazier, Ole Marten, Simone Kreimeier, Nan Luo, Brendan Mulhern, Wolfgang Greiner, A. Simon Pickard, Federico Augustovski, Lidia Engel, Luz Gibbons, Zhihao Yang, Andrea L. Monteiro, Maja Kuharic, Maria Belizan, Jakob Bjorner
Summary: This study explored the psychometric performance of candidate items for the EQ-HWB measure. The results showed that the items had good discrimination ability in groups with known health conditions, but lower discrimination ability in carers. Factor analysis and IRT provided valuable insights for item selection.
Article
Medicine, General & Internal
Katherine L. Tucker, Sam Mort, Ly-Mee Yu, Helen Campbell, Oliver Rivero-Arias, Hannah M. Wilson, Julie Allen, Rebecca Band, Alison Chisholm, Carole Crawford, Greig Dougall, Lazarina Engonidou, Marloes Franssen, Marcus Green, Sheila Greenfield, Lisa Hinton, James Hodgkinson, Layla Lavallee, Paul Leeson, Christine McCourt, Lucy Mackillop, Jane Sandall, Mauro Santos, Lionel Tarassenko, Carmelo Velardo, Lucy Yardley, Lucy C. Chappell, Richard J. McManus
Summary: The use of blood pressure self-monitoring with telemonitoring did not lead to significantly earlier detection of hypertension in pregnant individuals at higher risk of preeclampsia, compared to usual care.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Economics
Simone Kreimeier, David Mott, Kristina Ludwig, Wolfgang Greiner
Summary: This study developed a German EQ-5D-Y value set using the EQ-5D-Y valuation protocol and examined the differences in preferences for youth health between parents and non-parents. The findings provide important data for economic evaluations of pediatric healthcare interventions.
Article
Economics
Jill Carlton, Tessa Peasgood, Clara Mukuria, Janice Connell, John Brazier, Kristina Ludwig, Ole Marten, Simone Kreimeier, Lidia Engel, Maria Belizan, Zhihao Yang, Andrea Monteiro, Maja Kuharic, Nan Luo, Brendan Mulhern, Wolfgang Greiner, Simon Pickard, Federico Augustovski
Summary: This article describes the generation and selection of items in stage 2 and face validation in stage 3 of a large international project to develop a new generic measure, EQ-HWB, for economic evaluation estimating QALYs. The study involved mapping items from existing quality of life measures, refining potential terms and items, seeking input from key stakeholder groups, and conducting qualitative interviews for face validation. The research resulted in the generation of 687 items, with 64 items selected after predetermined criteria and modification based on feedback from stakeholders.
Article
Economics
John Brazier, Tessa Peasgood, Clara Mukuria, Ole Marten, Simone Kreimeier, Nan Luo, Brendan Mulhern, A. Simon Pickard, Federico Augustovski, Wolfgang Greiner, Lidia Engel, Maria Belizan, Zhihao Yang, Andrea Monteiro, Maja Kuharic, Luz Gibbons, Kristina Ludwig, Jill Carlton, Janice Connell, Stacey Rand, Nancy Devlin, Karen Jones, Aki Tsuchiya, Rosemary Lovett, Bhash Naidoo, Donna Rowen, Juan Carlos Rejon-Parrilla
Summary: This article presents the development process of the EQ-HWB measure, which encompasses health and wellbeing. Through literature reviews and qualitative interviews, 32 subdomains and 97 items were identified. After psychometric testing and stakeholder consultation, a final selection of 25 items for the EQ-HWB and 9 items for the short version was made.
Review
Medicine, General & Internal
Adeniyi Kolade Aderoba, Naima Nasir, Maria Quigley, Lawrence Impey, Oliver Rivero-Arias, Jennifer J. Kurinczuk
Summary: Pregnancy ultrasound has the potential to decrease the burden of adverse perinatal outcomes, but there is currently insufficient evidence to support universal obstetric ultrasound screening. This systematic review aims to summarize the evidence on key ultrasound parameters in late pregnancy to identify pregnancies at risk of adverse perinatal outcomes.
Article
Economics
Xiuqin Xiong, Kim Dalziel, Li Huang, Oliver Rivero-Arias
Summary: This study investigates the test-retest reliability of best-worst scaling (BWS) in eliciting preferences from adolescents compared to adults. The results show that both adolescents and adults can report their preferences with moderate reliability, and age does not significantly affect the reliability.
Article
Medicine, General & Internal
Oliver Rivero-Arias, John Buckell, Benjamin Allin, Benjamin M. Craig, Goher Ayman, Marian Knight
Summary: This study aims to evaluate the different elements of outcomes for pediatric surgical conditions and propose a summary metric to determine the successful treatment of these conditions. Data will be collected through the preferences of parents, individuals treated for surgical conditions, healthcare professionals, and the general public using paired comparisons and kaizen tasks.
Correction
Economics
Simone Kreimeier, David Mott, Kristina Ludwig, Wolfgang Greiner
Article
Economics
David J. Mott, Nancy J. Devlin, Simone Kreimeier, Richard Norman, Koonal K. Shah, Oliver Rivero-Arias
Summary: This paper compares different anchoring methods for value sets in discrete choice experiments (DCEs). The hybrid model value set is found to be closer to composite time trade-off (cTTO) values. Choosing an anchoring approach is challenging and may require value judgements. Researchers should seek input from relevant stakeholders and clearly justify their choice.
Article
Multidisciplinary Sciences
Benjamin Ruban-Fell, George Attilakos, Tao Haskins-Coulter, Christopher Hyde, Jeanette Kusel, Anne Mackie, Oliver Rivero-Arias, Basky Thilaganathan, Nigel Thomson, Cristina Visintin, John Marshall
Summary: This exploratory modelling study investigates the effects of different antenatal detection strategies for vasa praevia. The results suggest that a targeted screening approach for women with low-lying placentas can detect a substantial proportion of vasa praevia cases while avoiding over-detection of velamentous cord insertion. Further research is needed to explore the clinical and cost-effectiveness of this and other detection strategies.
Review
Economics
Pamela Gongora-Salazar, Stephen Rocks, Patrick Fahr, Oliver Rivero-Arias, Apostolos Tsiachristas
Summary: This study provides a comprehensive review of the application of multicriteria decision analysis (MCDA) in healthcare decision making. The use of MCDA in healthcare literature is increasing, with the majority of studies informing priority-setting decisions. Safety, cost, and quality of care delivery are the most frequently used criteria, but there are significant differences across decision contexts. A guide on how to conduct and report MCDA in healthcare, considering the specificities of different decision contexts and methods, needs to be developed.
Article
Public, Environmental & Occupational Health
May Ee Png, Miaoqing Yang, Sian Taylor-Phillips, Svetlana Ratushnyak, Nia Roberts, Ashley White, Lisa Hinton, Felicity Boardman, Abigail McNiven, Jane Fisher, Baskaran Thilaganathan, Sam Oddie, Anne-Marie Slowther, Jenny Shilton Osborne, Stavros Petrou, Oliver Rivero-Arias
Summary: This study systematically identified the benefits and harms included in economic assessments of antenatal and newborn screening programs. The diagnosis of screened conditions, life years and health status adjustments, and treatment were the main factors evaluated in both antenatal and newborn screening. Overdiagnosis and spillover effects were often overlooked.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Pediatrics
Xinyang Hua, Stavros Petrou, Victoria Coathup, Claire Carson, Jennifer J. Kurinczuk, Maria A. Quigley, Elaine Boyle, Samantha Johnson, Alison Macfarlane, Oliver Rivero-Arias
Summary: This study aimed to investigate the association between gestational age at birth and hospital admission costs from birth to 8 years of age. The study found that both birth admission and subsequent admission hospital costs decreased with increasing gestational age at birth. Differences in hospital admission costs between gestational age groups diminished with increasing age, particularly after the first 2 years following birth. Extremely preterm and very preterm children still had higher average hospital admission costs during the eighth year of life compared with children born at 40 weeks. Extremely preterm children had the highest 8-year cumulative hospital admission costs per child.
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)