Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

(2020) Manli Wang et al.   CELL RESEARCH

First Case of 2019 Novel Coronavirus in the United States

(2020) Michelle L. Holshue et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of Broad-Spectrum Antiviral Compounds by Targeting Viral Entry

(2019) Michela Mazzon et al.   Viruses-Basel

High-throughput Screening and Identification of Potent Broad-spectrum Inhibitors of Coronaviruses

(2019) Liang Shen et al.   JOURNAL OF VIROLOGY

Drug repurposing for new, efficient, broad spectrum antivirals

(2019) Moisés García-Serradilla et al.   VIRUS RESEARCH

Ebola Virus: Pathogenesis and Countermeasure Development

(2019) Wakako Furuyama et al.   Annual Review of Virology

Zika Virus Infection — After the Pandemic

(2019) Didier Musso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine

(2019) Andersen et al.   Viruses-Basel

Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection

(2019) Thomas R. Lane et al.   PLoS Neglected Tropical Diseases

Antiviral activity of cationic amphiphilic drugs

(2017) Cristiano Salata et al.   Expert Review of Anti-Infective Therapy

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection

(2017) Mukta Dutta et al.   Cell Reports

The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses

(2016) Eve-Isabelle Pécheur et al.   JOURNAL OF VIROLOGY

The cytokine storm of severe influenza and development of immunomodulatory therapy

(2015) Qiang Liu et al.   Cellular & Molecular Immunology

An Effective Synthesis Method for Tilorone Dihydrochloride with Obvious IFN-α Inducing Activity

(2015) Junren Zhang et al.   MOLECULES

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

Evaluation of Ebola Virus Inhibitors for Drug Repurposing

(2015) Peter B. Madrid et al.   ACS Infectious Diseases

A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents

(2013) Peter B. Madrid et al.   PLoS One

Small Molecule Activation of Adaptive Gene Expression

(2010) Rajiv R. Ratan et al.   Annals of the New York Academy of Sciences

Antiviral Properties, Metabolism, and Pharmacokinetics of a Novel Azolo-1,2,4-Triazine-Derived Inhibitor of Influenza A and B Virus Replication

(2010) I. Karpenko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

(2009) R. E. Martin et al.   SCIENCE