Insights about the structure of farnesyl diphosphate synthase (FPPS) and the activity of bisphosphonates on the proliferation and ultrastructure of Leishmania and Giardia

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Structural characterization of a lepidopteran type-II farnesyl diphosphate synthase from the spruce budworm, Choristoneura fumiferana : Implications for inhibitor design

(2018) Marie-Ève Picard et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Human leishmaniasis in Brazil: A general review

(2018) Laís Anversa et al.   Revista da Associacao Medica Brasileira

Giardiasis as a neglected disease in Brazil: Systematic review of 20 years of publications

(2017) Camila Henriques Coelho et al.   PLoS Neglected Tropical Diseases

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identical Assemblage of Giardia duodenalis in Humans, Animals and Vegetables in an Urban Area in Southern Brazil Indicates a Relationship among Them

(2015) Cristiane Maria Colli et al.   PLoS One

Genome profiling of sterol synthesis shows convergent evolution in parasites and guides chemotherapeutic attack

(2014) Matthias A. Fügi et al.   JOURNAL OF LIPID RESEARCH

Structural and thermodynamic basis of the inhibition ofLeishmania majorfarnesyl diphosphate synthase by nitrogen-containing bisphosphonates

(2014) Srinivas Aripirala et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate

(2014) Jaeok Park et al.   Acta Crystallographica Section F-Structural Biology Communications

Trypanosoma cruzi Response to Sterol Biosynthesis Inhibitors: Morphophysiological Alterations Leading to Cell Death

(2013) Rafael Luis Kessler et al.   PLoS One

Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model systemDictyostelium discoideum

(2012) James M. Nuttall et al.   BIOCHEMICAL JOURNAL

Farnesyl pyrophosphate synthase: a key enzyme in isoprenoid biosynthetic pathway and potential molecular target for drug development

(2012) Manoj K. Dhar et al.   New Biotechnology

The Genetic Structure of Leishmania infantum Populations in Brazil and Its Possible Association with the Transmission Cycle of Visceral Leishmaniasis

(2012) Gabriel Eduardo Melim Ferreira et al.   PLoS One

Tetrazolium salt based methods for high-throughput evaluation of anti-parasite chemotherapy

(2011) Cristina Henriques et al.   Analytical Methods

Identification of a Lysine Residue Important for the Catalytic Activity of Yeast Farnesyl Diphosphate Synthase

(2011) Marc J. C. Fischer et al.   PROTEIN JOURNAL

Molecular characterization of the cis-prenyltransferase of Giardia lamblia

(2010) Kariona A Grabińska et al.   GLYCOBIOLOGY

Molecular characterisation of species and genotypes of Cryptosporidium and Giardia and assessment of zoonotic transmission

(2008) L XIAO et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Leishmania amazonensis: Biosynthesis of polyprenols of 9 isoprene units by amastigotes

(2007) Denise Costa Arruda et al.   EXPERIMENTAL PARASITOLOGY