Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling

Structures of the heart specific SERCA2a Ca2+‐ATPase

(2019) Aljona Sitsel et al.   EMBO JOURNAL

Up-regulation of ANXA1 suppresses polymorphonuclear neutrophil infiltration and myeloperoxidase activity by activating STAT3 signaling pathway in rat models of myocardial ischemia-reperfusion injury

(2019) Can Zhao et al.   CELLULAR SIGNALLING

Sulodexide attenuates endoplasmic reticulum stress induced by myocardial ischaemia/reperfusion by activating the PI3K/Akt pathway

(2019) Danping Shen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway

(2019) Dawoud Sulaiman et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Nicotine reverses the enhanced renal vasodilator capacity in endotoxic rats: role of α7/α4β2 nAChRs and HSP70

(2019) Abdalla M. Wedn et al.   Pharmacological Reports

Antithrombin III Alleviates Myocardial Ischemia/Reperfusion Injury by Inhibiting Excessive Autophagy in a Phosphoinositide 3-Kinase/Akt-Dependent Manner

(2019) Kai-yu Huang et al.   Frontiers in Pharmacology

The critical role of the zinc transporter Zip2 (SLC39A2) in ischemia/reperfusion injury in mouse hearts

(2019) Luping Du et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Melatonin protects circulatory death heart from ischemia/reperfusion injury via the JAK2/STAT3 signalling pathway

(2019) Hongwen Lan et al.   LIFE SCIENCES

Dexmedetomidine post‐treatment attenuates cardiac ischaemia/reperfusion injury by inhibiting apoptosis through HIF‐1α signalling

(2019) Ke Peng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Matrine Protects Cardiomyocytes from Ischemia/Reperfusion Injury by Regulating HSP70 Expression Via Activation of the JAK2/STAT3 Pathway

(2018) Suping Guo et al.   SHOCK

Annexin A5 reduces infarct size and improves cardiac function after myocardial ischemia-reperfusion injury by suppression of the cardiac inflammatory response

(2018) Rob C. M. de Jong et al.   Scientific Reports

Nrf2 activation and down-regulation of HMGB1 and MyD88 expression by amnion membrane extracts in response to the hypoxia-induced injury in cardiac H9c2 cells

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Hsp70 Interacts with Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinase 2 To Regulate p38MAPK Stability and Myoblast Differentiation during Skeletal Muscle Regeneration

(2018) Wei Fan et al.   MOLECULAR AND CELLULAR BIOLOGY

Endothelin receptor mediated Ca 2+ signaling in coronary arteries after experimentally induced ischemia/reperfusion injury in rat

(2017) Sarah Brøgger Kristiansen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

High mobility group box 1 protein attenuates myocardial ischemia reperfusion injury via inhibition of the p38 mitogen-activated protein kinase signaling pathway

(2017) Yan-Hong Zhou et al.   Experimental and Therapeutic Medicine

Dexmedetomidine Protects Cardiomyocytes against Hypoxia/Reoxygenation Injury by Suppressing TLR4-MyD88-NF-κB Signaling

(2017) Jin-meng Gao et al.   Biomed Research International

Osthole decreases renal ischemia-reperfusion injury by suppressing JAK2/STAT3 signaling activation

(2016) Lin-Na Luo et al.   Experimental and Therapeutic Medicine

Reperfusion therapy for acute myocardial infarction: Concepts and controversies from inception to acceptance

(2015) Klaus Peter Rentrop et al.   AMERICAN HEART JOURNAL

Cardioprotective function of mitochondrial-targeted and transcriptionally inactive STAT3 against ischemia and reperfusion injury

(2015) Karol Szczepanek et al.   BASIC RESEARCH IN CARDIOLOGY

Ca2+ Sparks and Ca2+ waves are the subcellular events underlying Ca2+ overload during ischemia and reperfusion in perfused intact hearts

(2015) Alicia Mattiazzi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Honokiol protects against renal ischemia/reperfusion injury via the suppression of oxidative stress, iNOS, inflammation and STAT3 in rats

(2015) YONGWU YU et al.   Molecular Medicine Reports

Decreasing or increasing heat shock protein 72 exacerbates or attenuates heat-induced cell death, respectively, in rat hypothalamic cells

(2015) Kao-Chang Lin et al.   FEBS Open Bio

Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial Fibrillation

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Extracellular Hsp70: Export and Function

(2014) Antonio De Maio   CURRENT PROTEIN & PEPTIDE SCIENCE

CaMKII-dependent phosphorylation of cardiac ryanodine receptors regulates cell death in cardiac ischemia/reperfusion injury

(2014) Mariano N. Di Carlo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

p38α regulates SERCA2a function

(2013) Leena Kaikkonen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Chaperone machines for protein folding, unfolding and disaggregation

(2013) Helen Saibil   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway

(2012) Weixun Duan et al.   BASIC RESEARCH IN CARDIOLOGY

Calcium-mediated cell death during myocardial reperfusion

(2012) D. Garcia-Dorado et al.   CARDIOVASCULAR RESEARCH

Berbamine Protects the Heart From Ischemia/Reperfusion Injury by Maintaining Cytosolic Ca2+ Homeostasis and Preventing Calpain Activation

(2012) Cai-Mei Zhang et al.   CIRCULATION JOURNAL

Interleukin-17A Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Cardiomyocyte Apoptosis and Neutrophil Infiltration

(2012) Yu-Hua Liao et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

ISCHEMIC POSTCONDITIONING DURING REPERFUSION ATTENUATES INTESTINAL INJURY AND MUCOSAL CELL APOPTOSIS BY INHIBITING JAK/STAT SIGNALING ACTIVATION

(2012) Shi-Hong Wen et al.   SHOCK

Extracellular Heat Shock Protein 70 Induces Cardiomyocyte Inflammation and Contractile Dysfunction via TLR2

(2011) Sumeet Mathur et al.   CIRCULATION JOURNAL

Role of p38 inhibition in cardiac ischemia/reperfusion injury

(2011) Sarawut Kumphune et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Ginseng protects rodent hearts from acute myocardial ischemia–reperfusion injury through GR/ER-activated RISK pathway in an endothelial NOS-dependent mechanism

(2011) Hua Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pathogenesis of Myocardial Ischemia-Reperfusion Injury and Rationale for Therapy

(2010) Aslan T. Turer et al.   AMERICAN JOURNAL OF CARDIOLOGY

Lipopolysaccharide pretreatment protects against ischemia/reperfusion injury via increase of HSP70 and inhibition of NF-κB

(2010) Yong-wei Yao et al.   CELL STRESS & CHAPERONES

Cardioprotection by CaMKII-δB Is Mediated by Phosphorylation of Heat Shock Factor 1 and Subsequent Expression of Inducible Heat Shock Protein 70

(2009) Wei Peng et al.   CIRCULATION RESEARCH

Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury

(2007) Weidong Chai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM