Synthesis of Pyridines, Quinolines, and Pyrimidines via Acceptorless Dehydrogenative Coupling Catalyzed by a Simple Bidentate PAN Ligand Supported Ru Complex

A ruthenium hydrido chloride complex (I) supported by a simple, heteroleptic bidentate PAN ligandi(Lzl)scontaining a diarYIPilosPh iile anda benzannulated phenanthridine Is rep'donor arm orted-theiIn presence of base, comPlex cat aye multicomponent reactions using alcohol. precursors. toallY diverse molecules including pyridines quinolinPer,s7idaunccsle tructtir PNYrotimabildYiiilLes1 via not bear readily.fdeg)ePriraottiovneatc:cluPB1rinugnstPeadthawcia.Ii' acceptorless dehydrogenative c or basic groups common to transition metal catalysts caPable of ese sorts of transformationsi suggesting metal ligand cooperativity not play a significant role in the catalytic reactivity of i,, A and structurally characterized, and its role in acceptorrare example of an Y12-aldehyde adduct was i of ruthenium ssolated le dehydrogenative coupling reactions is discussed